Conclusions: Long-circulating liposome is a good drug delivery system for vincristine.
结论：长循环脂质体是长春新碱的理想载体。
Such as Vincristine Sulfate, Vinorelbine Bitartrate, NHDC and Hesperidin Methyl Chalcone.
例如硫酸长春新碱、酒石酸长春瑞宪，NHDC。
OBJECTIVE To study the physical and chemical stability of vincristine sulfate-blank liposomes.
目的考察三瓶装硫酸长春新碱脂质体中空白脂质体的物理、化学稳定性。
They also found that this synergy occurred with trastuzumab and either paclitaxel or vincristine.
他们发现这种协同作用也发生在脂质体和长春新碱或紫杉醇。
Objective To find out if vincristine can be used to treat the chronic primary thrombocytopenic puripura.
目的：探讨长春新碱治疗慢性原发性血小板减少性紫癫的可行性。
Objective To investigate the release rate and pharmacodynamics in vitro of of vincristine sulfate liposomes.
目的考察硫酸长春新碱脂质体的体外释放度及其药效。
OBJECTIVE To prepare vincristine sulfate liposomes and to develop a method for determining its entrapment efficiency.
目的制备硫酸长春新碱脂质体，建立包封率测定方法。
To investigate the impact of vincristine (VCR) on the cell proliferation and cycle in nasopharyngeal carcinoma cell line CNE-2Z.
探讨长春新碱(VCR)对鼻咽癌cne鄄2 Z细胞增殖和周期的影响。
Objective To optimize the technological parameters of separation and purification of vinblastine and vincristine from Gatharanthus Roseus.
目的优选分离纯化长春花中长春碱和长春新碱的最佳工艺参数。
Microtubule dynamics test showed that S47 inhibited microtubule polymerization. Vincristine had a mechanism of action similar to that of S47.
微管微丝动力学试验证实，S47能抑制微管微丝的聚合，与长春新碱作用机理相同。
Conclusions The process is simple and reasonable with good reproducibility. It is effective to enrich highly purified vinblastine and vincristine.
结论该工艺简便合理，重复性良好，能得到高纯度的长春碱和长春新碱。
OBJECTIVE To prepare vincristine sulfate liposomes by active loading method, and study the influence of different factors on the entrapment efficiency.
目的采用主动载药法制备硫酸长春新碱脂质体，考察包封率的影响因素。
There are more than 100 kinds of alkaloids in vinca plant, including anhydrovinblastine, vinblastine, vincristine and other anti-tumor medicine used in clinic, etc.
如果对长春花的研究不是应用药理学方法的话，长春新碱的发现恐怕还要推迟好多年。
Objective: to study whether the anti-apoptotic action is reversed by tetrandrine in a combination with vincristine in human breast carcinoma MCF-7 multidrug-resistant cells.
目的：研究粉防己碱与长春新碱合用能否逆转人乳腺癌M CF 7多药耐药细胞的抗凋亡作用。
And we've clearly seen children's performance in academic and on neuropsychological tests really be adversely or negatively affected when the child is getting the vincristine.
当孩子们服用长春新碱，我们很明显看到他们在学术和神经心理测试上表现变差。
Vincristine is an antineoplastic agent for intravenous use only; inadvertent intrathecal administration of vincristine may cause severe neurologic damage, and often is fatal.
长春新碱为抗肿瘤药，仅用于静脉注射，误行鞘内注射可致严重神经损害，并常造成死亡。
In the second study, Dr. Ingrid Wertz of Genentech in San Francisco and her colleagues focused on certain widely prescribed anti-cancer drugs, including Taxol and vincristine.
在第二项试验中，来自旧金山Genentech公司的IngridWertz博士和他的同事研究的是包括紫杉醇和长春新碱在内的一大类处方类抗癌药物。
PURPOSE: the current standard therapy for patients with diffuse large B-cell lymphoma (DLBCL) is rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP).
背景：目前，弥漫大b细胞性淋巴瘤(DLBCL)的标准治疗方案为利妥昔单抗联合CHOP方案化疗(R - CHOP)。
Chemotherapy was given according to the protocol which consisted of lomustine, cisplatinum and vincristine after radiotherapy, but the patients were not given intrathecal chemotherapy.
所有患儿于放疗后接受长春新碱、环己亚硝脲、顺铂方案化疗，所有患者均未行鞘内化疗。
Objective To evaluate the reasons for intrathecal administration of vincristine, the characteristics of patients with nerve damage, and the effective rescue measures and outcome prognosis.
目的评价误行鞘内注射长春新碱事件的发生原因、患者神经损害的特点、抢救措施和预后。
Objective To evaluate the reasons for intrathecal administration of vincristine, the characteristics of patients with nerve damage, and the effective rescue measures and outcome prognosis.
目的评价误行鞘内注射长春新碱事件的发生原因、患者神经损害的特点、抢救措施和预后。
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