While the two-hit hypothesis is useful conceptually, making predictions for particular individuals is still a challenge.

虽然这“两步假设法”理论上行得通，可是要预测特定个体，依然是一个挑战。

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Background and objective: the hypothesis of "two hit" model suggests that at least two classes of gene mutations are responsible for the leukemogenesis.

背景与目的：“两次打击”学说认为，白血病的发生常常累及两大类以上基因的突变。

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Background and objective: the hypothesis of "two hit" model suggests that at least two classes of gene mutations are responsible for the leukemogenesis.

背景与目的：“两次打击”学说认为，白血病的发生常常累及两大类以上基因的突变。

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