The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录,参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
一些小鼠还有肿瘤抑制基因p 53缺陷,这种缺陷突变存在与大约一半的人类肺癌。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
他们发现当用DADS治疗时,有名的肿瘤抑制基因p53阻止了细胞循环 。
Cruciferous vegetables contain compounds that preferentially destroy ineffective mutant p53 tumor suppressor proteins, but leave the good ones alone.
十字花科的蔬菜含有一类物质,能够降解由p 53突变体产生的那些效率低下的抗肿瘤蛋白,而保留高效的蛋白。
In 2005, researchers at Sloan-Kettering reported that the gene could stop massive tumor growth in prostate cancer even when another tumor suppressor, known as P53, was turned off.
早在2005年,斯隆·凯特琳中心的研究人员就曾报道了在另一种叫做P 53的肿瘤抑制基因关闭时,该基因甚至仍然可以阻止前列腺癌大肿瘤生长。
As Thompson began to study the gene, he found that it was a target for a tumor suppressor gene called p53, which is a major controller of cell activity in prostate and other cancers.
当Thompson开始研究这个基因时,他发现RTVP - 1基因是肿瘤抑制基因p53的靶基因,p 53是前列腺癌及其他癌症细胞活性的最主要控制者。
In 2005, researchers at Sloan-Kettering reported that the gene could stop massie tumor growth in prostate cancer een when another tumor suppressor, known as P53, was turned off.
早在2005年,斯隆·凯特琳中心的研究人员就曾报道了在另一种叫做P 53的肿瘤抑制基因关闭时,该基因甚至仍然可以阻止前列腺癌大肿瘤生长。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
P53 gene is the most prominent tumor suppressor gene in human cancer among those genes that have been found till now.
p 5 3基因是至今为止发现的与人类肿瘤相关性最高的基因。
The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations.
p53肿瘤抑制蛋白在细胞响应DNA损伤和其它基因组异常的过程中发挥重要作用。
Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学:p53肿瘤抑制基因突变,第11p15基因座杂和性丢失。
Pathology: p53 tumor suppressor gene mutation, loss of heterozygosity (LOH) at 11p15 locus. PAX-FKHR gene fusion.
病理学:p53肿瘤抑制基因突变,第11p15基因座杂和性丢失。
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