A tumor suppressor that promotes cancer cell growth?
肿瘤抑制基因促进肿瘤生长?
A study of tumor suppressor genes on chromosome 9 in glioblastomas.
胶质母细胞瘤9号染色体肿瘤抑制基因的研究。
Endogenous angiogenesis inhibitors act as tumor suppressor proteins.
内源性血管生成抑制剂可作为一种抑癌蛋白。
The advances in the study of tumor suppressor genes in gliomas were reviewed.
作者就目前在脑胶质瘤中研究较多的抑癌基因的进展作了综述。
There probably existed candidate tumor suppressor gene (s) around D5S592 and D5S471.
D5S471和D5S592附近可能存在食管癌的候选抑癌基因。
SIPA1 probably inhibits the metastasis and recurrence of HCC as a tumor suppressor gene.
SIPA1在HCC中发挥肿瘤抑制基因的作用,且对抑制HCC的复发转移有重要作用。
To investigate the suppression effect of tumor suppressor gene in lung adenocarcinoma cells.
探讨肿瘤抑制基因对肺腺癌细胞生长的抑制作用。
In contrast, undifferentiated carcinomas rarely exhibit structurally altered tumor suppressor genes.
相反,未分化癌极少表现出抑癌基因结构的改变。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
他们发现当用DADS治疗时,有名的肿瘤抑制基因p53阻止了细胞循环 。
We demonstrate that Chd5 functions as a tumor suppressor in vivo and implicate deletion of CHD5 in human cancer.
我们证明Chd5在活体中作为抑癌基因发挥作用而且在人类恶性肿瘤与CHD5的缺失有关。
Mutations in so-called tumor suppressor genes can result in loss of growth control, which in turn may result in cancer.
称之为肿瘤抑制基因的突变可以引起生长失去控制,从而可能导致癌症。
Objective: To study the expressions of pro-onc and tumor suppressor genes in gastric cancer by cDNA expression array.
目的:从基因水平了解正常胃和胃癌组织原癌基因和抑癌基因表达的分子机制。
Objective To investigate the expression and significance of tumor suppressor gene protein PTEN in malignant melanoma.
目的探讨pten基因蛋白在恶性黑素瘤中的表达及其意义。
A gene homologous to the human putative tumor suppressor gene QM, designated OSQM1, was isolated from rice Oryza sativa l.
基因组文库中分离到一个与人类肿瘤抑制基因QM具有同源性的基因,命名为OSQM1。
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
一些小鼠还有肿瘤抑制基因p 53缺陷,这种缺陷突变存在与大约一半的人类肺癌。
Objective to investigate the expression of tumor suppressor PTEN mRNA in human glioma and to elucidate its clinical significance.
目的探讨抑癌基因pten在脑胶质瘤组织中的表达情况及其临床意义。
The UCSD researchers also studied mice that were missing a tumor suppressor gene, which is a gene that ACTS to prevent cell growth.
UCSD研究者也对丢失肿瘤抑制基因的小鼠进行研究。肿瘤抑制基因可以阻止细胞生长。
Recently researchers find that a new tumor suppressor imprinted gene ARHI(NOEY2)is involved in the onset and progression of cancer.
近年来研究表明,一种新的抑癌印迹基因ARHI(NOEY2)的异常参与了一些肿瘤的发生。
Objective: To explore the alteration and the possible mechanism of tumor suppressor gene P16 in the progression of ovarian carcinoma.
目的:探讨卵巢癌病变中P16抑癌基因的改变和可能的作用机制。
Heat Shock Proteins may contribute to cell cycle regulation by interacting with proto-oncogene products or tumor suppressor gene products.
热休克蛋白可能有助于细胞周期调控通过与原癌基因的产品或抑癌基因的产品。
Aim: To evaluate the clinical value of MSP (methylation specific PCR) in detection of tumor suppressor genes methylation in the colorectal cancer.
目的:评价特异性甲基化pcr (msp)分析法检测抑癌基因高甲基化对结、直肠癌的诊疗价值。
Cruciferous vegetables contain compounds that preferentially destroy ineffective mutant p53 tumor suppressor proteins, but leave the good ones alone.
十字花科的蔬菜含有一类物质,能够降解由p 53突变体产生的那些效率低下的抗肿瘤蛋白,而保留高效的蛋白。
Purpose To investigate the possible role of loss of heterozygosity (LOH) of tumor suppressor genes in the development of primary hepatic lymphoma (PHL).
目的探讨肿瘤抑制基因杂合性缺失(LOH)在肝原发性淋巴瘤(PHL)发生中的作用。
The different mechanisms, such as the activation of oncogenes, the inactivation and mutation of tumor suppressor gene, antiapoptosis and so on are involved in .
原癌基因的激活,抑癌基因的失活、突变,抗细胞凋亡等不同的机制都可能参与其中。
Objective To investigate the effect and mechanisms of tumor suppressor gene PTEN on the induction of anoikis of human bladder transitional carcinoma cells BIU-87.
目的研究抑癌基因pten对人膀胱癌细胞株biu - 87失巢凋亡的影响并探讨其可能的机制。
Quite a few kinds of genes such as susceptibility gene, oncogene and tumor suppressor genes have been found with implications for diagnosis, therapy and prognosis.
其中涉及多种基因异常,包括易感基因、癌基因、抑癌基因等,对于乳腺癌的诊断、治疗及预后判断均具有提示作用。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
虽然许多原癌基因和肿瘤抑制基因被广泛表达,这些基因的突变与特定的器官或细胞类型的癌有关。
The discovery of oncogenes and tumor suppressor genes, and the research of signal transduction pathway yield profound insights into the mechanisms of carcinogenesis.
癌基因和抑癌基因的发现,细胞信号传导通路的阐明,极大地丰富了人们对细胞癌变机制的认识。
Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.
PTEN肿瘤抑制因子在乳腺癌中虽常呈失表达,但并不是通过基因突变或促进子甲基化而实现的,因此其失表达的机制还不清楚。
Expression of the PTEN tumor suppressor is frequently lost in breast cancer in the absence of mutation or promoter methylation through as yet undetermined mechanisms.
PTEN肿瘤抑制因子在乳腺癌中虽常呈失表达,但并不是通过基因突变或促进子甲基化而实现的,因此其失表达的机制还不清楚。
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