Purpose to analyze the expression of thyroid transcription factor-1 (TTF-1) in the metastatic pulmonary adenocarcinoma cells in serous effusions.
目的探讨甲状腺转录因子1 (TTF 1)在浆膜腔积液肺腺癌细胞中的表达,为肺腺癌的诊断和鉴别诊断提供新的依据。
Thyroid transcription factor 1(TTF-1) is a homeobox domain transcription factor of the NKX2 family.
甲状腺转录因子1是含一同源盒域的转录因子,属于NKX2家族。
Objective to investigate the biologic significance of thyroid transcription factor-1 (TTF-1) and surfactant protein a (SP-A) and SP-B expression in pulmonary sclerosing hemangioma (PSH).
目的探讨甲状腺转录因子1 (TTF 1)和表面活性蛋白a、B (SP A,SP B)在肺硬化性血管瘤(PSH)中表达的生物学意义。
Methods 40 patients with lung cancer were studied to detect TTF-1 gene by using reverse transcription-polymerase chain reaction assay (RT-PCR).
方法采用逆转录—聚合酶链反应(RT -PCR)方法检测40例患者的肺癌组织ttf - 1基因的表达。
Objectives To study the expression of surfactant protein B(SP-B)and thyroid transcription factor 1(TTF-1)and evaluate the role in neonatal hyaline membrane disease(NHMD).
目的探讨表面活性蛋白B(SP-B)与甲状腺转录因子(TTF-1)在新生儿肺透明膜病中的表达及其意义。
Objective To investigate the change of the expression of TTF-1 and SP-A in lung tissue of ALI rats induced by LPS.
目的探讨内毒素(LPS)诱导的急性肺损伤(ALI)大鼠肺组织甲状腺转录因子-1(TTF-1)、肺表面活性物质相关蛋白-A(SP-A)表达的变化。
Methods The TTF-1 expression intensity (in positive units, PU) in paraffin-embedded tissue blocks was determined using immunohistochemical SP method in combination with Motic Images System.
方法石蜡包埋切片,应用免疫组织化学SP法及麦克奥迪真彩色病理分析图像分析系统,对TTF-1表达强度的阳性单位(PU)进行定量分析。
TTF, 1 was expressed in the majority of benign and malignant thyroid diseases. The immnostaining of TTF, 1 was located in nuclear of cells, TTF, 1 was a sensitive marker for thyroid follicular cells.
TTF蛳1在甲状腺常见良恶性病变中阳性率均高,特异地表达在细胞核,是一种特异的甲状腺滤泡细胞标志物。
Mammalian reproductive ability also can be influenced potentially by TTF-1.
TTF - 1基因还对哺乳动物的繁殖性能有潜在的影响。
TTF-1 is related to development of the thyroid gland and regulates and controls transcriptions of thyroglobulin(TG), thyroperoxidase(TPO), and thyrotropin(TSH) receptor genes.
其与甲状腺的发育有关,并且调控甲状腺球蛋白、甲状腺过氧化物酶和促甲状腺激素受体基因的转录。
Homogeneous analysis demonstrated that nucleotide and amino acids sequences of sheep TTF-1 gene between different species mammal are comparatively conservative.
序列同源性分析表明,绵羊ttf - 1基因的核酸和蛋白质序列在不同哺乳动物之间有很高的同源性,分子在进化上均相当保守。
TTF-1 expression is most frequently seen in carcinomas of thyroid and lung origin.
最常见其在甲状腺和肺来源的癌中表达。
TTF-1 expression is most frequently seen in carcinomas of thyroid and lung origin.
最常见其在甲状腺和肺来源的癌中表达。
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