Functional annotation is highly dependent on sequence similarity to other known genes or proteins as the majority of initial "first-pass" functional annotation on a genomic scale is transitive.
功能注释高度依赖于与其他已知基因或蛋白质的序列相似性，因为在一个基因组规模上的大多数最初的“首过”功能注释是可传递的。
Functional annotation is highly dependent on sequence similarity to other known genes or proteins as the majority of initial "first-pass" functional annotation on a genomic scale is transitive.
功能注释高度依赖于与其他已知基因或蛋白质的序列相似性，因为在一个基因组规模上的大多数最初的“首过”功能注释是可传递的。
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