Since diarrhea and skin toxicity limit the use of this drug in some patients, the researchers looked for a specific variation in the ABCG2 gene that could disrupt the function of the ABCG2 protein.
由于腹泻和皮肤毒性限制了此类药物的应用，研究人员期望发现ABCG2基因特异性的突变从而能够阻断ABCG2蛋白的功能。
Although biodegradation is regarded as an economical and efficacious purified method in the treatment of industry waste water and sewage, the high toxicity of nitrobenzene would limit its application.
虽然生物降解对于工业和生活废水而言是一种经济、有效的净化方法，但在处理硝基苯废水时其高毒性限制了它的使用。
Then the radiological toxicity of spallation products was studied by applying the concept of annual limit of intake(ALI).
采用年摄入量限值（ALI）标准定义的放射性毒性，对散裂靶中散裂产物产生的放射性毒性进行研究分析。
The invention employs the side effects of the opioid formulation to permit patients to self-limit drug intake, thereby avoiding toxicity while achieving analgesia.
本发明利用了该阿片样物质制剂的副作用使得患者可以自我限制药物摄入，从而在达到止痛效果的同时避免了中毒。
The invention employs the side effects of the opioid formulation to permit patients to self-limit drug intake, thereby avoiding toxicity while achieving analgesia.
本发明利用了该阿片样物质制剂的副作用使得患者可以自我限制药物摄入，从而在达到止痛效果的同时避免了中毒。
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