Methods The expressions of MMP 2 and TIMP 2 in 47 cases of astrocytoma were detected by immunohistochemical method.
方法采用免疫组织化学方法检测4 7例星形细胞瘤组织中MMP2和TIMP 2的表达情况。
Objective to study the expression of MMP 2 and TIMP 2 in gastric cancer tissues and the relation to the aggregated degree, metastasis and prognosis.
目的探讨基质金属蛋白酶-2 (MMP - 2)和组织基质金属蛋白抑制剂- 2 (TIMP - 2)在胃癌组织中的表达及其与侵袭程度、淋巴结转移的关系。
AIM: to investigate the expression of MMP 2 and TIMP 2 in tumor invasion and local metastasis or as a prognostic factor in patients with pancreatic carcinoma.
目的:研究MMP2,TIMP 2在胰腺癌组织中的表达,探讨其与胰腺癌的侵袭转移及预后的关系。
Objective to investigate the expressions of matrix metalloproteinase 2 (MMP 2) and tissue inhibitor of metalloproteinase 2 (TIMP 2) in astrocytoma and their relations to the pathological grade.
目的研究基质金属蛋白酶2 (MMP 2)和金属蛋白酶组织抑制剂2 (TIMP 2)在人脑星形细胞瘤中的表达及其与病理分级的关系。
Conclusion MMP-2, MMP-9 and TIMP-1 play an important role in the infiltrative metastasis of seminoma and may act as one of the factors to evaluate prognosis.
结论MMP - 2、MMP - 9、TIMP - 1在人睾丸精原细胞瘤的浸润转移过程中起重要作用,有可能成为估计预后的指标之一。
Conclusion the expression of TIMP-1, -2 in human dental pulp cell and tissue is detected, and this provides the basis for further studying on the mechanism of TIMP in dental pulp.
结论TIMP 1、2在人牙髓成纤维细胞及牙髓组织均有表达,为进一步研究TIMP在牙髓组织中的作用机理提供实验依据。
Results the MMP-2 and TIMP-2 expression levels in the carotid tissues of the control group was low, and elevated in the experimental group.
结果MMP - 2和TIMP - 2在对照组兔颈动脉组织中低水平表达,在实验组兔颈动脉组织中表达的水平升高。
Expression of Matrix Metalloproteinase-2, -9 and Their Inhibitors TIMP-1, -2 on Lens Epithelial Cells of Aged-related Cataract.
基质金属蛋白酶-2,9及其抑制因子- 1,2在老年性白内障晶状体上皮细胞的表达。
Objective to study the expressions of metalloproteinase 2 (MMP-2) and tissue inhibitors of metalloproteinase 2 (TIMP-2) in lung cancer, and their relationships with microvessel density (MVD).
目的:研究基质金属蛋白酶-2 (MMP - 2)和组织基质金属蛋白酶抑制剂- 2 (TIMP - 2)在人肺癌组织中的表达及其与微血管密度(MVD)的关系。
Objective to investigate the expressions of matrix metalloproteinase-2 (MMP-2) and the tissue inhibitor of metalloproteinases-2 (TIMP-2) in human esophageal squamous cell carcinoma (ESCC).
目的探讨基质金属蛋白酶- 2 (MMP - 2),组织金属蛋白酶抑制剂- 2 (TIMP - 2)在食管鳞癌中的表达及其临床意义。
Conclusions The abnormal expressions of MMP? 1, 2, 3 and TIMP? 1, 2, which resulted in degradation disorder of extracellular matrix, could induce degeneration of cartilage.
结论在骨关节炎中MMP1、2、3和TIMP 1、2表达异常,引起细胞外基质异常降解,是导致关节软骨发生组织学退变的原因之一。
Methods a rat model of cerebral aneurysm was established. The dynamic changes of MMP-2, MMP-9 and TIMP-1 expression were examined in the process of aneurysm formation.
方法制作肾性高血压大鼠脑动脉瘤模型,系统动态观察脑动脉瘤形成过程中MMP - 2、MMP - 9及其特异性抑制物(TIMP - 1)表达的变化。
Oral administration and local injection of tea polyphenol could markedly reduce expression of VEGF and increase expression of TIMP-2 in S180 bearing tumor.
茶多酚口服及局部注射组可明显降低S180荷瘤vegf表达水平、增加TIMP - 2表达水平。
ConclusionThe expression of MMP-2, TIMP-1 and TIMP-2 are closely correlated with the development of the invasive activity of human astrocytoma.
结论MMP - 2、TIMP - 1和TIMP - 2在星形细胞肿瘤组织中的表达与星形细胞肿瘤的侵袭性生物学行为的演进密切相关。
Objective To study the expression and significance of MMP-2 and TIMP-2 in colorectal carcinoma.
目的探讨基质金属蛋白酶-2(MMP-2)和组织基质金属蛋白抑制剂-2(TIMP-2)在大肠癌组织中的表达及其意义。
Purpose To understand the relationship between the expression of MMP-2, TIMP-2 and the clinical significance in human colorectal carcinoma.
目的研究基质金属蛋白酶-2(MMP-2)及其抑制物组织基质金属蛋白酶抑制剂-2(TIMP-2)在大肠癌进展中的作用及其临床意义。
Objective To study the significance of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) expressing in craniopharyngiomas.
目的研究基质金属蛋白酶MMP-2及其抑制剂TIMP-2在颅咽管瘤中的表达意义。
Objective To investigate the effects of overdosed fluoride on the expression of MMP-20 and TIMP-2 in rat incisor.
目的研究过量氟对大鼠切牙生长过程中基质金属蛋白酶-20(MMP-20)和基质金属蛋白酶组织抑制剂-2(TIMP-2)表达的影响,探讨氟斑牙的发病机制。
Methods The test group and control groups' expression of MMP-2, TIMP-2 were detected by immunohistochemical method, then the ratios of MMP-2/TIMP-2 were calculated.
方法应用免疫组化的方法检测新辅助化疗组和对照组肺癌组织中MMP—2和TIMP—2蛋白的表达,并分别计算其表达比率。
Gene TIMP-2 has inhibitory effect to the changes of biology and morphology in guinea pig form deprivation myopia model.
因此TIMP - 2基因对于豚鼠形觉剥夺性近视模型形态学和生物学改变有一定的抑制效应。
Conclusion: The imbalance of MMP-2 and TIMP-2 may be more important in malignant parotid gland tumor, down-expression of TIMP-2 may be an early biomarker of metastasis and invasion of tumor.
结论:在腮腺恶性肿瘤中,MMP 2与TIMP 2之间的平衡失调可能更为重要,TIMP 2表达的下调可作为肿瘤早期转移和浸润的标志之一。
Objective to observe the dynamic changes of MMP-2 and TIMP-2 after middle cerebral artery (MCA) ischemia in rats and evaluate the neuroprotective effects of Captopril on focal cerebral ischemia.
目的:观察大鼠大脑中动脉(MCA)缺血后MMP - 2及TIMP - 2的动态变化及开博通对局灶性脑缺血大鼠的脑保护作用。
Conclusion: MMP-2 and MMP-9 be involved in the invasion of the normal human cytotrophoblast cells, while TIMP-1 and TIMP-2 make this invasion controllable.
结论:MMP一2、MMP一9参与了正常早孕滋养细胞的侵袭的过程,而TIMP-1、TIMP一2使滋养层细胞以一种可控制的形式侵袭。
The expression level of TIMP-2 in lung cancer tissue was lower than that in para-cancer tissue(P<0.001), there was no significant difference between various pathological types of lung cancer(P<0.05);
肺癌组织TIMP-2的表达低于癌周肺组织(P<0.001),在各种不同病理类型肺癌中的表达差异无显著性(P>0.05),并发淋巴结转移的肺癌组织表达较低(P<0.05)。
Conclusion the overexpression of MMP-2, TIMP-1 and TIMP-2 are closely correlated to development of the invasion activity of human astrocytoma.
结论MMP - 2、TIMP - 1和TIMP - 2在星形细胞肿瘤中的表达与星形细胞肿瘤的侵袭性生物学行为的演进亲密相关。
The expression of TIMP-2 was negatively correlated to lymph node metastasis. Co...
MMP - 2的表达与淋巴结转移呈正相关,而TIMP - 2的表达则相反。
The expression of TIMP-2 was negatively correlated to lymph node metastasis. Co...
MMP - 2的表达与淋巴结转移呈正相关,而TIMP - 2的表达则相反。
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