Objective To investigate the action of recombinant protein of tissue inhibitor of metalloproteinase-3(TIMP-3)on apoptosis of MC3T3-E1 osteoblasts.
目的研究组织金属蛋白酶抑制因子3（TIMP-3）重组蛋白对MC3T3-E1成骨细胞凋亡的影响。
Conclusions The abnormal expressions of MMP? 1, 2, 3 and TIMP? 1, 2, which resulted in degradation disorder of extracellular matrix, could induce degeneration of cartilage.
结论在骨关节炎中MMP1、2、3和TIMP 1、2表达异常，引起细胞外基质异常降解，是导致关节软骨发生组织学退变的原因之一。
Objective To investigate the relationship between the ratio of MMP-3 to TIMP-1 and articular cartilage injury after ischemia-reperfusion.
目的探讨缺血再灌注后关节软骨中MMP - 3/TIMP - 1比例变化与软骨损伤的关系。
Objective To investigate the relationship between the ratio of MMP-3 to TIMP-1 and articular cartilage injury after ischemia-reperfusion.
目的探讨缺血再灌注后关节软骨中MMP - 3/TIMP - 1比例变化与软骨损伤的关系。
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