Conclusion the drug release mainly depends on the gel erosion.
结论药物释放主要取决于凝胶溶蚀。
The drug release and permeation were observed to be dependent on some factors.
药物的体外释放和渗透受到多种处方因素的调节。
The study examine the drug release mechanism of famotidine chitosan microcapsule.
初步研究了法莫替丁-甲壳胺微囊的释药机理。
Taking Ib as a model drug, the drug release behaviors of the capsules were studied.
以布洛芬为模型药物,初步研究了微囊载体的缓释行为。
OBJECTIVE To prepare thymopentin microspheres and investigate the drug release in vitro.
目的制备胸腺五肽微球并对其体外释放进行考察。
The drug release kinetics were also investigated in different releasing mediums(deionic water, 0.
目的制备盐酸氨溴索药物树脂复合物并对其体外释药动力学进行考察。
The influences of different pore-forming agents and their amount on the drug release were compared.
比较了缓释层中不同致孔剂及其用量对微丸释药速率的影响。
Methods the influencing factors on the drug release were investigated by use of similarity factor method.
方法采用相似因子法考察影响药物释放速率的因素,并考察了其释药机理。
The drug release model and the envelop rates of the testing group remained stable within the storage date.
试验组在贮存期内的释药模式及包封率均维持稳定。
The drug release experiment of compression spring model with pure magnetic mechanism trigger was successful.
用纯磁力机构的压缩弹簧释放方式成功模拟了药物释放试验。
Objective To prepare aciclovir sustained-release pellets and investigate the drug release mechanism in vitro.
目的制备阿昔洛韦缓释微丸,并对其体外释药情况进行研究。
The effect of some factors on the drug release from the HPMC sustained-release matrix tablet was investigated.
考察了影响多索茶碱缓释骨架片释药的因素。
The results showed that the drug release from MTX liposomes was in conformity with the first-order dynamic equation.
结果表明:甲氨喋呤脂质体的药物释放速率符合一级动力学方程。
Methods Coating prescription was optimized by uniform design and the drug release characteristic was tested in vitro.
方法采用均匀设计优化包衣处方,对度米芬渗透泵片进行体外释放度试验。
RESULTS the ratio of pectin-calcium chloride and mass ratio of drug-matrix were important factors on the drug release.
结果骨架中果胶-氯化钙的质量比、药物-骨架质量比以及骨架的组成均可显著影响药物的释放。
Aim to prepare the micelles of stearic acid grafted chitosan oligosaccharide and investigate the drug release from micelles.
目的考察阳离子型壳寡糖硬脂酸嫁接物胶团的理化性质及载药胶团的体外药物释放。
A mathematical model describing the drug release from porous polymer was established by using the species continuity equation.
以组分的连续性方程为基础,建立了药物从多孔骨架聚合物系统中释放的数学模型。
CONCLUSION The TFH tablet has sustained release property in vitro. The drug release pattern is in accord with Weibull distribution.
结论醋柳黄酮缓释片缓释效果显著,体外释放符合威布尔分布模型。
The effects of different drug loadings on the drug release rate were simulated and compared with other data to validate this model.
模拟不同载药量对药物释放速率的影响并与其它数据进行比较,以此来验证此模型。
Objective To investigate the preparation technology and the drug release mechanism of Breviscapine chitosan-alginate microcapsules.
目的考察灯盏花素壳聚糖- 海藻酸钠微囊的制备工艺和释药机制。
Factors influencing the drug release rate, including drug loading, species and amount of additives, hardness, particle size were studied.
考察载药量、填充剂种类和用量、硬度、辅料粒径等因素对药物释放的影响。
The drug release rate and concentration was related with the concentration of MTX in compound but not with the thickness and shape of CPC.
MTX释放浓度及速度与MTX在骨水泥中的包埋量有关,与骨水泥的厚度及形状无关。
Methods Orthogonal experiment was carried out to optimize the formulation. Several mathematic models were used to imitated the drug release.
方法采用正交试验法进行处方优化,用数学模型拟合释放曲线。
Methods The non-membrane model was introduced to observe the influence on the drug release and gel erosion for surface area and shaking frequency.
方法采用无膜溶出模型,考察释放面积、振荡频率对眼用凝胶溶蚀及药物释放的影响。
The mechanism of release results from the matrix rode and drug diffusion of matrix by describing the drug release curve using Ringer-Peppas model.
释药机制探讨表明:经膜控和骨架杂化控制释药的模型用一级动力学方程解释较好。
CONCLUSION the drug release percents and the tumor control rates of CCNU-TSL are improved significantly compared with lomustine solution in vitro.
结论洛莫司汀热敏脂质体在相变温度时,体外释药明显增加,体外抑瘤效果明显提高。
The factors that control the drug release character of the tablets were investigated. The drug release mechanism of the formulation was also studied.
分别考察了上述因素对于控释片体外释放度的影响以及药物释放机制。
OBJECTIVE to improve the drug release reproducibility of elementary osmotic pump tablets and to investigate its drug release mechanism with a new method.
目的研究渗透泵型控释片剂的释药规律及释药重现性,探索考察释药机制的新方法。
In the present study, silymarin sustained-release tablets were developed to delay the drug release, reduce dosing frequency and improve patient compliance.
本文研制了水飞蓟素缓释片,以延缓药物的释放,减少给药次数,提高患者的顺应性。
Conclusion The drug release of sodium ferulate single-layer osmotic pump controlled release tablets is stable and had obvious characteristic of zero release.
结论阿魏酸钠单层渗透泵控释片工艺稳定,呈明显的零级释药特征。
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