CONCLUSION: the synthetic method of sodium taurocholate is acceptable.
结论：合成法制备牛磺胆酸钠结果令人满意。
OBJECTIVE: To synthesize sodium taurocholate and study its pharmacological effects.
目的：化学合成牛磺胆酸钠，并对其药理作用进行研究。
Methods Retrograde pancreatic duct injection of 5% sodium taurocholate to establish ANP models.
方法逆行胰管注射5%的牛磺胆酸钠溶液制作ANP模型。
Methods SAP model was induced by retrograde injection of 5% sodium taurocholate into pancreatic duct.
方法：逆行胰胆管注射5%牛磺胆酸钠制作SAP模型。
Methods The rat model of ANP was established by retrograde bile-pancreatic duct injection of 5% sodium taurocholate.
方法逆行胆胰管注射5 %牛磺胆酸钠溶液制成ANP模型。
Methods The model of ANP was established in 90 rats by retrograde injection of 5% sodium taurocholate into biliopancreatic duct.
方法采用5%牛磺胆酸钠逆行胆胰管注射建立大鼠ANP肝损害模型，90只大鼠，随机分成三组。
Methods a model of experimental PE in AHNP was induced by retrograde injection of 5 % sodium taurocholate into the pancreatic duct.
方法应用5%牛磺胆酸钠逆行胰胆管注射诱发大鼠ahnp并发脑组织损害模型。
RESULTS: the yield of synthetic product, the infrared spectrum of which was conformable to the chemical structure of sodium taurocholate, was over 50%.
结果：合成法制备牛磺胆酸钠收率在50%以上，其红外光谱与结构相符。
METHODS: Antitussive test, expectorant test and antiasthmatic test were made with sodium taurocholate prepared by conjugating starting compound cholic acid with taurine.
方法：以胆酸为起始物，结合牛磺酸制备牛磺胆酸钠，并对其进行镇咳、祛痰和平喘实验。
Methods: Acute pancreatitis model was induced by intraperitoneal injection of cerulein or retrograde infusion of 5% sodium taurocholate into the bilipancreatic duct in SD rats.
方法： 分别采用腹腔注射雨蛙肽和胆胰管逆行注射5%牛磺胆酸钠建立大鼠轻症、重症急性胰腺炎模型。
Methods: A model of experimental PCH induced acute hemorrhagic necrotizing pancreatitis(AHNP) was induced by retrograde injection of 5% sodium taurocholate into the pancreatic duct.
方法：应用5 %牛磺胆酸钠逆行胰胆管注射诱发大鼠AHNP并发脑组织损害模型。
Under constant intravenous infusion of taurocholate to keep the bile acid pool steady, the effect of LHA injection of TRH on bile secretion was studied in rats with acute bile duct fistulae.
用具备急性胆瘘的大鼠在人工维持胆汁酸池恒定的条件下，观察LHA微量注射TRH对胆汁分泌的影响。
Under constant intravenous infusion of taurocholate to keep the bile acid pool steady, the effect of LHA injection of TRH on bile secretion was studied in rats with acute bile duct fistulae.
用具备急性胆瘘的大鼠在人工维持胆汁酸池恒定的条件下，观察LHA微量注射TRH对胆汁分泌的影响。
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