Recent studies of immune tolerance have focused on the role of a subset of t cells, called regulatory t cells (Tregs).
关于免疫耐受的近期研究集中在一种称为调节性T细胞(Treg)的T细胞亚群的作用。
Immunologists now recognize a four-point response system of helper t cells: Th 1, Th 2, Th 17 and regulatory t cells.
免疫学家现在认识到了辅助性T细胞(以下代号th)的四点反应系统:Th1, Th2,Th17和调节性T细胞。
Regulatory T cells can be found in tolerated grafts and contribute to the acquisition of a state of privilege in those tissues.
在产生免疫耐受的移植物中可发现调节性T淋巴细胞,并对移植组织具有保护性作用。
The approach, published April 8 in Immunity, exploits the immune system's built-in safety mechanism—a group of regulatory T cells whose job is to squelch overactive immune responses.
发表于4月8号《Immunity》上的文章利用免疫系统的内置安全装置,一组起调控作用的T细胞来抑制过度的免疫反应。
What exactly is wrong with the genes in these regulatory t cells? What are they doing that they shouldn't be doing?
那在调节性T细胞中这些基因具体出什么问题了?它们产生了什么不该产生的作用?
Summary: The potency of regulatory t cells is impressive, but unexplained.
总结:调节性T淋巴细胞的效能值得注重,但尚无法解释。
NKT cells are a type of t cell that exert profound and diverse regulatory effects in disease, from autoimmunity to responses to pathogens and cancer.
NKT细胞是T细胞中的一类,对疾病(从自身免疫到对病原体的响应再到肿瘤)有形式多样的重要调节作用。
Pathogenesis of autoimmune disease such as systemic lupus erythematosus, role of regulatory T cells in inhibition and treatment of pathological injury caused by autoimmune disease.
自身免疫疾病如红斑狼疮等风湿性疾病的发病机制,重点在于调节性T细胞对自身免疫病理损伤的抑制作用和治疗作用。
Recently, accumulating evidences have shown that regulatory t cells play a key role both in maintenance of self tolerance and tolerance to allograft.
近年来,调节性T细胞在自身耐受和抑制同种异体排斥反应中的作用受到越来越多的重视。
Regulatory t cells, if given to individuals receiving transplants, may help suppress the rejection response.
如果给与一个接受移植的人调节T细胞,可能会有助于抑制排斥反应。
ObjectiveTo investigate the roles of immune regulatory T cells and cytokines in immune disorders in pediatric aplastic anemia(AA).
目的评价免疫调节T细胞和细胞因子在再生障碍性贫血(再障)细胞免疫功能紊乱中的作用。
Objective to investigate the role of CD4 + CD25 + regulatory t cells in immunological pathogenesis of Kawasaki disease (KD).
目的探讨CD 4 + CD 25 +调节性T细胞在川崎病(KD)免疫发病机制中的作用。
In many autoimmune diseases like systemic lupus erythematosus, regulatory t cells are abnormal significant in quantity or function.
在很多自身免疫性疾病如系统性红斑狼疮中调节性T细胞的数量和(或)功能存在显著异常。
Summary: The potency of regulatory T cells is impressie, but unexplained.
总结:调节性T淋巴细胞的效能值得注重,但尚无法解释。
Objective to observe the pathology of AIDS-related lymphadenopathy and its relationship to the expression and distribution of CD4 + CD25 + regulatory t cells in lymphoid node tissue.
目的探讨艾滋病患者淋巴结组织中CD 4 + CD 25 +调节性T细胞的表达、分布及其与病理改变的相关性。
Conclusions CD4 + CD25 + regulatory t cells exist in lymphoid node tissue of patients with HIV infection. Their amounts decrease or deplete along with the progression of AIDS-related lymphadenopathy.
结论艾滋病患者淋巴结中存在有CD 4 +CD 25 +调节性T细胞,随着淋巴结病变的进展其数量减少或耗竭。
The highly accurate identification and isolation of regulatory t cells was made possible using sophisticated flow cytometry equipment at the Centenary Institute.
由于对t调控细胞识别和分离的高度准确性使得我们研究所采用流式细胞术成为可能。
Recent evidence showed that there are two ways that could contribute to the peripheral homeostasis of CD4 + CD25 + regulatory t cells, in which some functional molecules may be involved.
新近的研究显示CD 4 + CD 25 +调节性T细胞主要通过两种机制来维持其外周细胞库,一些功能分子参与其中。
Regulatory DCs can induce regulatory T cells, inhibit T cell proliferation or induce T cell anergy.
目前发现,调节性DC可诱导调节性T细胞产生,抑制T细胞增殖或诱导T细胞增殖阻滞。
More and more research proved that CD4+CD25+ regulatory T cells (Treg cells) play an important role in immune tolerance in these years.
近年来,越来越多的研究表明CD4+CD25+调节性T细胞在免疫耐受的过程中起着非常重要的作用。
This article summarizes the relations between immune tolerance and apoptosis, dendritic cell and regulatory t cells.
本文对免疫耐受与细胞凋亡、调节性T细胞及树突状细胞的研究进展进行综述。
CD4+CD25+ regulatory T cell is a crowd of cells, which can regulate and suppress the immune response.
CD4+CD2+5调节性T细胞是一群具有免疫调节或免疫抑制功能的细胞。
ABSTRACT: Objective to observe the pathology of AIDS-related lymphadenopathy and its relationship to the expression and distribution of CD4 + CD25 + regulatory t cells in lymphoid node tissue.
摘要:目的探讨艾滋病患者淋巴结组织中CD 4 + CD 25 +调节性T细胞的表达、分布及其与病理改变的相关性。
Objective to investigate the role of antigen-specific regulatory t cells in spontaneous diabetes of NOD mice.
目的探讨抗原特异调节的T细胞在非肥胖型糖尿病(NOD)小鼠自发性糖尿病中的作用。
Profound immunologic changes occur during pregnancy, involving a polarization of t helper cells towards a dominance of Th2 and regulatory t cell effector responses in both mother and fetus.
意义深远的免疫性的改变发生在怀孕期间,对于在母亲和胎儿中多数的th2和调整的t细胞效应器都反映包括了th细胞的极化。
Methods are also provided for generating tolerogenic dendritic cells and regulatory t cells.
本发明也提供了产生致耐受性树突细胞和调节性T细胞的方法。
Conclusion: Peripheral blood CD4 + CD25 + regulatory t cells levels are correlated with the progression of HCV infection.
结论:HCV感染者外周血cd4 +CD 25 +调节性T细胞水平与疾病进程具有相关性。
"We think that cord blood is a very rich source of these regulatory t cells, and there was a measurable increase in these cells in patient? S blood through six months after the infusion," said Dr.
Schatz博士说:“我们认为脐带血富含这些调节性T细胞,而且在注射后六个月内可以测到这些细胞数量在增长。”
The possible mechanisms may be that T cells induce regulatory immuno activity targeting autoimmune T cells.
其机制可能与T细胞免疫诱导了针对自身反应性T细胞的调节性免疫应答有关。
The possible mechanisms may be that T cells induce regulatory immuno activity targeting autoimmune T cells.
其机制可能与T细胞免疫诱导了针对自身反应性T细胞的调节性免疫应答有关。
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