Objective to establish an improved radioligand assay of insulin autoantibody (IAA) and to investigate the diagnostic role of IAA in type 1 diabetes (T1DM).
目的：建立胰岛素自身抗体(IAA)的改良放射免疫分析法，并探讨IAA对1型糖尿病(T1DM)的诊断价值。
Objective To analyze the clinical characteristics of type 1 diabetes mellitus(T1DM) in children and explore its late complications and influence growth and development.
目的分析儿童1型糖尿病（T1DM）的临床特征，探讨该病对儿童生长发育的影响程度及后期并发症发生的情况。
Conclusions a clone of murine GAD65 is successfully constructed. It is a basis step for further construction of expression plasmid that expresses GAD65 and for immunologic intervention of T1DM.
结论成功的克隆了小鼠gad65基因，为构建GAD65基因疫苗以及糖尿病的免疫干预治疗打下基础。
Conclusions the increased number of osteoclast might be one of the reasons for the development of osteoporosis in rat with T1DM, while Alendronate can inhibit in vitro OLCs formation in these rats.
结论破骨细胞形成增加可能是1型糖尿病骨质疏松的原因之一，阿仑膦酸钠抑制1型糖尿病骨质疏松大鼠体外培养的OLC的形成。
Conclusions the increased number of osteoclast might be one of the reasons for the development of osteoporosis in rat with T1DM, while Alendronate can inhibit in vitro OLCs formation in these rats.
结论破骨细胞形成增加可能是1型糖尿病骨质疏松的原因之一，阿仑膦酸钠抑制1型糖尿病骨质疏松大鼠体外培养的OLC的形成。
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