AIM To study on the alterations of t suppressor cell function in patients with ulcerative colitis (UC) and Crohn's disease (CD) and their clinical significance.
目的研究溃疡性结肠炎(UC)和克隆病(CD)患者T抑制细胞的活性及其临床意义。
Objective To explore the changes of CD8 + t cell subtypes especially CD8 + CD28 -t suppressor cells in rats with experimental colitis induced by 2, 4-dinitrofluorobenzene (DNFB).
目的探讨CD 8 +T细胞亚群尤其是CD 8 + CD2 8 - T抑制细胞在2,4二硝基氟苯(DNFB)大鼠实验性结肠炎模型中的变化及其可能作用。
In addition to the suppressor cell dysfunction the distribution of T lymphocyte subsets is also abnormal and the OKT_4/OKT_8 ratio is significantly decreased in patients with HBV infection.
此外还证实HBV感染患者抑制性T细胞在功能和表型上的不一致，即抑制性T细胞功能低下而OKT_8的抑制性T细胞百分率增高。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
他们发现当用DADS治疗时，有名的肿瘤抑制基因p53阻止了细胞循环 。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
虽然许多原癌基因和肿瘤抑制基因被广泛表达，这些基因的突变与特定的器官或细胞类型的癌有关。
To investigate the inhibition of tumor cell proliferation by natural suppressor (NS) cells in human bone marrow.
目的研究人骨髓细胞中自然抑制细胞的抗肿瘤效应。
A tumor suppressor that promotes cancer cell growth?
肿瘤抑制基因促进肿瘤生长？
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
癌基因，肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。使人们对肿瘤发生和发展的认识也日趋深入。
Such chromosomal abnormalities inactivate tumor - suppressor genes that are critical for controlling cell growth.
这种染色体异常使控制细胞生长的关键肿瘤抑制基因失活。
Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.
原癌基因的突变导致的过度刺激细胞周期，而突变的肿瘤抑制基因，会导致在这一功能的控制过度活动。
Heat Shock Proteins may contribute to cell cycle regulation by interacting with proto-oncogene products or tumor suppressor gene products.
热休克蛋白可能有助于细胞周期调控通过与原癌基因的产品或抑癌基因的产品。
It has been proved that the occurrence of oncogenesis is in close relationship with the oncogene activation, the tumor suppressor gene inactivation and the disorder of cell cycle modulation.
目前在分子水平上的研究显示肿瘤的发生与癌基因的激活和抑癌基因的失活以及细胞周期调节失控密切相关。
Objective To study effects of the exogenous wild-type PTEN tumor suppressor gene on in vitro adhesion, migration and invasion of the highly metastatic mucoepidermoid carcinoma cell line M3SP2.
目的探讨外源野生型PTEN抑癌基因对人高转移性黏液表皮样癌细胞系m 3sp2体外黏附、迁移和侵袭特性的影响。
The UCSD researchers also studied mice that were missing a tumor suppressor gene, which is a gene that ACTS to prevent cell growth.
UCSD研究者也对丢失肿瘤抑制基因的小鼠进行研究。肿瘤抑制基因可以阻止细胞生长。
To investigate the effects of tumor suppressor in lung cancer-1 (TSLC1) on cell aggression, tumor formation and capability of metastasis in human prostatic carcinoma cell line T3B.
研究肺癌抑癌基因1 (TSLC1)对人前列腺癌t 3 B细胞侵袭、成瘤和转移能力的影响。
Human cancer suppressor gene, protein encoded therein, expression vector containing the same, and cell transformed by the vector.
人抑癌基因，其编码的蛋白，含有其的表达载体和由该载体转化的细胞。
The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression.
肿瘤抑制蛋白p21Waf1/Cip1可以作为细胞周期的抑制因子。
As Thompson began to study the gene, he found that it was a target for a tumor suppressor gene called p53, which is a major controller of cell activity in prostate and other cancers.
当Thompson开始研究这个基因时，他发现RTVP - 1基因是肿瘤抑制基因p53的靶基因，p 53是前列腺癌及其他癌症细胞活性的最主要控制者。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
The strategy targeted to the tumor suppressor gene that regulates the cell cycle directly, obtained satisfactory results, and provided a reliable theory for lung cancer gene therapy.
本项基因治疗策略以直接调控细胞周期的抑癌基因为靶向治疗基因，为肺癌基因治疗提供了可靠的理论依据。
Objective To investigate the mutation of Von Hippel-Ldau(VHL)tumor suppressor gene in peatients with primary sporadic human renal cell carcinoma(RCC).
目的探讨国人原发性散发性肾透明细胞癌中VHL抑癌基因突变及其意义。
PHB1 is 30kda tumor suppressor protein involved in cell cycle control (1).
PHB1是一个30kda的肿瘤抑制蛋白，参与细胞周期控制(1)。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录，参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录，参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
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