Inhibition of STAT3 activity may be a new therapy for breast cancer.
抑制STAT3的激活可能成为治疗乳腺癌的一种新的途径。
Baseline levels of high EGFR and low STAT3 may be associated with antitumor effects.
水平以上的EGFR高表达和STAT3的低表达可能与抗肿瘤效应有关的。
The STAT3 protein was mainly expressed in cytoplasm and nucleus of breast cancer cells.
STAT 3蛋白主要表达于细胞质和细胞核。
The time and space phase pattern of STAT3 protein was consistent with that of cell apoptosis.
STAT3蛋白高表达与神经元凋亡两者的部位和时间段基本一致。
Binding of FLT3L to its cognate tyrosine kinase receptor, FLT3, activates STAT3 and STAT5 (1, 3).
FLT3L结合到与它同源的酪氨酸激酶的受体FLT3结合激活STAT3和STAT 5 (1,3)。
Objective to investigate regulation of activated STAT3 on apoptosis of Hodgkin's lymphoma (HL) cells.
目的探讨STAT3的活化对霍奇金淋巴瘤(HL)细胞凋亡的调控作用。
In para-carcinoma gallbladder tissue, those STAT3-positive cells may be potential malignant pre-cancerous cells.
在癌旁胆囊组织中，那些STAT3蛋白阳性的胆囊细胞可能是潜在的恶性癌前细胞。
The researchers found that celecoxib decreased STAT3 phosphorylation to cause the liver cancer cells to self-destruct.
研究者发现，塞来昔布通过降低STAT 3磷酸化，使肝癌细胞走向自毁。
They also found that celecoxib blocked exogenous interleukin-6-induced STAT3 phosphorylation and nuclear translocation.
同时，他们还发现，塞来昔布阻断外源性白介素诱导的STAT 3磷酸化及核转位。
Conclusion the expression of STAT3 protein may be closely related to the early development of the retina in the postnatal hamster.
结论STAT 3蛋白的表达及变化可能与视网膜生后早期发育密切相关。
This article reviewed the characteristics of molecular biology, the relations with tumor and the progress of STAT3 gene in cervical cancer.
现就STAT 3蛋白的生物学特性、与肿瘤的关系及其在宫颈癌中的研究现状予以综述。
Action of signal transduction of mediated cytokine indicated by STAT3 raises in motoneurons of facial nerve nucleus after facial nerve injury.
提示面神经损伤后面神经核运动神经元内由信号转导子和转录激活子3介导的细胞因子的信号转导作用增加。
STAT3, which is associated with inflammation and cellular transformation, is activated in human HCC tissue but not in normal human liver tissues.
STAT3是联系炎症与细胞转化的桥梁，在肝癌组织中有活化，而在正常肝脏却没有类似表现。
Therefore, we believe that celecoxib can be combined with other anticancer drugs to reduce drug resistance caused by interleukin-6 STAT3 signals.
因此，我们推测通过联合塞来昔布可以降低化疗药耐受现象的发生。
OBJECTIVE: in this study, we first examined the expression of STAT3 in thyroid carcinoma and its relationship with clinicopathological characteristics.
目的：分析STAT 3在甲状腺癌中的表达及其与临床病理特征的相关性研究。
CONCLUSION: the gene expression of STAT3 and 5 in the hippocampal neurons reinforced by hypoxia plays an important role in brain injury caused by hypoxia.
结论：低氧增强海马神经元细胞中STAT 3,5基因的表达，在低氧所致的脑损伤中可能发挥重要作用。
The mechanism of action may be related to the decreased expression of JAK2 and STAT3 of hepatic tissue and blocking of JAK2/STAT3 signal transduction pathway.
肝复康对肝纤维化有疗效，其作用机制可能与降低肝组织JAK2和STAT3的表达，阻断JAK2/STAT3信号通路有关。
However, there is no literature reported regarding if there is STAT3 expression and whether it participates in embryo liver development both at home and abroad.
但是在胚胎肝脏发育中是否有STAT3的表达，STAT 3是否参与了胚胎肝脏中期发育过程，目前国内外尚无文献报道。
STAT3, as a member of signal transducers and activators of transcription (STATs) family, which has been recognized as one of the common pathways in cancer cells.
信号转导及转录活化因子3（STAT3）是STAT家族成员之一，也是肿瘤组织中的常见通路。
Signal transducer and activator of transcription 3 (STAT3) plays a central role in mediating signals related to cell growth, differentiation, survival and movement.
信号转导和转录激活蛋白Stat3在细胞的生长、分化、存活和运动过程中扮演重要角色。
As a transcription factor, STAT3 participated in the control of their target genes' expression and forms a complicated network together with other transcription factors.
作为转录因子的STAT 3参与很多基因的表达和调控，并与其他转录因子形成复杂的调控网络。
Conclusion the expressions of STAT3 increased might indicate the transmission course in ischemic nerve cell signal, and play a key role in neuron apoptosis of ischemic brain injury.
结论STAT 3蛋白表达增强可能介导缺血性脑损伤的信号转导过程，其在脑缺血损伤神经元凋亡过程中起关键作用。
Objective To investigate the activation law of signal transducers and activators of transduction-3(STAT3) and whether cytokine IL-6 can activate STAT3 in acute lung injury (ALI) of rats.
目的探讨大鼠急性肺损伤（ALI）过程中，信号转导和转录活化因子-3（STAT3）的活化，及其与细胞因子白介素-6（IL-6）的相关性。
AIM to explore the changes in the activation of signal transducer and activator of transcription-3 STAT3 and DNA binding activation in facial nerve nucleus after facial nerve injury and repair.
目的：探讨面神经损伤与修复条件下，面神经核运动神经元信号转导子和转录激活子3的活性以及DNA结合活性的变化。
STAT3 may become a new cancer treatment target. Blocking STAT3 signal may reduce tumor cell invasion and metastasis, and inhibit tumor cell grow, which can provide a new idea for cancer treatment.
STAT 3有可能成为肿瘤治疗中一个新的治疗靶位，阻断STAT 3信号传导通路可能降低肿瘤细胞的侵袭和转移、抑制肿瘤细胞生长，可为肿瘤治疗提供新的思路。
STAT3 may become a new cancer treatment target. Blocking STAT3 signal may reduce tumor cell invasion and metastasis, and inhibit tumor cell grow, which can provide a new idea for cancer treatment.
STAT 3有可能成为肿瘤治疗中一个新的治疗靶位，阻断STAT 3信号传导通路可能降低肿瘤细胞的侵袭和转移、抑制肿瘤细胞生长，可为肿瘤治疗提供新的思路。
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