Sphingosine 1 phosphate (SPP) is an important second messenger involved in cell growth and cell death.

鞘氨醇1磷酸(SPP)是重要的细胞第二信使，影响细胞的生长和死亡。

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Herein we review the chemical studies on sphingosine and related lipid derivatives, with focus on their chemical synthesis.

本文主要综述了鞘氨醇等衍生脂质的化学研究，特别是它们的化学合成进展。

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Sphingosine kinase (SPK) is a key enzyme catalyzing the formation of sphingosine 1 phosphate (S1P), which is a lipid messenger with strong angiogenic activity.

细胞内鞘氨醇激酶（SPK）是催化鞘氨醇生成1-磷酸鞘氨醇（S1P）的限速酶。

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Objective To investigate the effect and mechanism of sphingosine 1-phosphate (S1P) on action potential (AP) and voltage-dependent potassium current (KV) in isolated guinea pig ventricular myocytes.

目的研究1 -磷酸鞘氨醇(S1P)对豚鼠心室肌细胞动作电位(AP)及电压依赖性钾电流(KV)的作用及其机制。

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Objective To investigate the effect and mechanism of sphingosine 1-phosphate (S1P) on action potential (AP) and voltage-dependent potassium current (KV) in isolated guinea pig ventricular myocytes.

目的研究1 -磷酸鞘氨醇(S1P)对豚鼠心室肌细胞动作电位(AP)及电压依赖性钾电流(KV)的作用及其机制。

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