• Dripping pill is a dosage form of solid dispersion.

    滴丸制剂是一种固体分散体。

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  • Conclusion Etodolac solid dispersion can significantly increase the dissolution rate.

    结论依托度酸固体分散体能显著提高依托度酸的溶出速率。

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  • Results: The in vitro dissolution rates of ISDN solid dispersion were faster than ISDN.

    结果:固体分散体能加快药物的溶出速率,最佳比例为1∶7。

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  • The present invention relates to a tanshinone solid dispersion and its preparation method.

    本发明提供了一种丹参酮固体分散物及其制备方法。

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  • Preparation methods had little effect on the dissolution rates of daidzein solid dispersion.

    不同的固体分散体制备方法对药物的溶出度影响不大。

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  • The results of DSC and PXRD showed that the quercetin in solid dispersion was amorphous form.

    热差分析及粉末X衍射结果表明固体分散体中槲皮素呈非结晶形式;

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  • CONCLUSION Itraconazole solid dispersion can significantly increase it's solubility and dissolution rate.

    结论:伊曲康唑固体分散体能明显提高伊曲康唑的溶解度及体外溶出速率。

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  • Aim In order to increase bioavailability of Artemisinin'S dosage form, solid dispersion of Artemisinin was prepared.

    目的:研制青蒿素缓释固体分散物,提高其制剂的生物利用度。

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  • Results:Acetaminophen combined with PEG 6000 by hydrogen bond, and acetaminophen was dispersed in solid dispersion.

    结果:对乙酰氨基酚与PEG 6000之间存在氢键效应,对乙酰氨基酚高度分散在PEG 6000中。

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  • Method: Bomeolum Syntheticum and PEG 6000 mixing preparative solid dispersion and packed capsules, toxicity was tested.

    方法:将冰片用水溶性辅料聚乙二醇6000制成固体分散体,并填装入胶囊,进行毒理试验。

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  • It is indicated that the solubility of Nisoldipine capsule is improved by the utilization of solid dispersion technology.

    结果证明,采用固体分散技术能提高尼索地平的体外溶出度。

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  • Droppills were made by solid dispersion technology with the bases of PEG4000 and PEG6000, which has established the optimum moulding craft.

    采用固体分散技术以聚乙二醇4000和聚乙二醇6000作为基质,甲基硅油作为冷却剂优化了滴丸成型工艺。

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  • Methods Etodolac solid dispersion was prepared with PEG as carrier by solvent-fusion method and identified by differential thermal analysis.

    方法选用聚乙二醇为载体,采用溶剂-熔融法制备依托度酸固体分散体,通过差热分析对固体分散体进行鉴定。

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  • OBJECTIVE The solid dispersion method was adopted to enhance the dissolution rate of nifedipine (NFDP) which is a poorly water-soluble drug.

    目的采用制剂技术提高难溶性药物硝苯地平体外溶出速率。

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  • Conclusion: Raman spectrometry which is fast, direct and non-destructive is an ideal method in examining the dispersivity of solid dispersion.

    结论:拉曼光谱法快速、直接、对样品无损伤,是一种新的理想的检查固体分散体分散性的方法。

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  • Objective To prepare adefovir dipivoxil solid dispersion from poorly-soluble adefovir dipivoxil so as to improve its dissolution rate in vitro.

    目的 将难溶性药物阿德福韦酯制备成固体分散体,以增加体外溶出度。

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  • Conclusion: Raman spectrometry which is fast, direct and non-destructive is an ideal method for examining the dispersivity of solid dispersion.

    结论:拉曼光谱法快速、直接、对样品无损伤,是一种新的理想的检查固体分散体分散性的方法。

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  • It is prepared by supercritical extraction, flocculating and alcohol settling cyclodextrin investing and solid dispersion preparation technique.

    该制剂的制备采用了超临界提取及絮凝醇沉的工艺及环糊精包埋与固体分散体制剂技术。

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  • OBJECTIVE To improve in vitro release of acemetacin, the technology of solid dispersion was used and acemetacin was prepared as solid dispersion.

    目的:利用固体分散技术制备阿西美辛固体分散体,增加其溶解度和溶出速度。

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  • Methods: the solid dispersion was prepared by solvent method. The solubility, the dissolution rate and the derivative thermogravimetry (DTG) were determined.

    方法:采用溶剂法制备固体分散体,进行溶解度、溶出速率测定,导数热重分析(DTG)。

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  • The solid dispersion technology was employed in research and development of Nisoldipine capsule. Further more, the dissolution rate was detected upon the capsule.

    采用固体分散技术研究和制备了尼索地平胶囊,对其进行了溶出度测定。

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  • OBJECTIVE: to prepare tinidazole solid dispersion using the technology of solid dispersion, and to increase the dissolubility and the dissolution rate of tinidazole.

    目的:利用固体分散技术制备替硝唑固体分散体,增加替硝唑溶解度和溶出速度。

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  • CONCLUSION The solid dispersion in PVP k30 improves the solubility of curcumin. These findings show a potential application of curcumin SDs as an anti-ulcerogenic drug.

    结论PVP固体分散体可有效提高姜黄素的溶解性,同时应用在治疗胃溃疡具有很好的开发前景。

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  • Methods: HPMC and stearic acid were used to prepare melatonin controlled-release bilayer tablets by application of solid dispersion method and double compression technology.

    方法:以hpmc、硬脂酸为骨架材料,采用固体分散技术和双层压片工艺,制备褪黑素双层控释片。

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  • Objective: to investigate whether the combined carrier is superior to the single carrier in improving dissolution of poorly insoluble water drug and prepare a fast released solid dispersion.

    目的:考察水溶性联合载体在增加难溶性药物的溶出速率上是否优于单一载体,并制备速释型固体分散体。

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  • Cefuroxime Axetil granules were prepared by solid dispersion technique with gelatin as the main materials for masking the bitter. The bitter after masking and the stability were investigated.

    采用明胶作为主要掩味材料,利用固体分散技术制备头孢呋辛酯颗粒剂,并进行掩味效果及稳定性考察。

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  • METHODS Preparing the solid dispersion by melting method at different drug-to-PEG ratios with different PEG moleculars and studying the preparation with dissolution rate in vitro and DSC method.

    方法以不同分子量不同比例的聚乙二醇为载体,以熔融法制备固体分散体,并进行体外溶出度研究和DSC扫描。

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  • METHODS Preparing the solid dispersion by melting method at different drug-to-PEG ratios with different PEG moleculars and studying the preparation with dissolution rate in vitro and DSC method.

    方法以不同分子量不同比例的聚乙二醇为载体,以熔融法制备固体分散体,并进行体外溶出度研究和DSC扫描。

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