ABSTRACT Objective: To study the influence of sodium valproate on plasma fibrinogen.
目的：研究丙戊酸钠对血浆纤维蛋白原的影响。
OBJECTIVE to explore the pathogenesis of thrombocytopenic purpura caused by sodium valproate treatment.
目的探讨丙戊酸钠致血小板减少性紫癜可能发生机制。
Objective: to compared the pharmacokinetics of sodium valproate suppository with sodium valproate tablets.
目的：比较丙戊酸钠栓剂与片剂的药代动力学特征。
Objective To investigate the clinical efficacy and side effects of sodium valproate in the treatment of alcohol withdrawal reaction.
目的探讨丙戊酸钠对酒精戒断反应的临床疗效及副反应。
ConclusionBorneol can enhance the permeability of blood-brain barrier to sodium valproate, but has small influence on blood concentration.
结论冰片可提高血脑屏障对丙戊酸钠的通透性，但对血药浓度影响较小。
Neither sodium valproate nor Verapamil showed any effect on action potential amplitude, overshoot, resting potential and phase o upstroke velocity.
丙戊酸钠和异搏定对动作电位幅度、超射值、静息电位、O期最大除极速度均无明显影响。
Conclusion: Lower dose sodium valproate is effective in the treatment of TD caused by antipsychotics. Close attention should be paid to the platelet count.
结论：丙戊酸钠治疗抗精神病药所致TD有效，但以低剂量为宜，应注意监测血象。
AIM: To observe the effects of sodium valproate in the repair of rat sciatic nerve injury through the drug experiment of the model of sciatic nerve injury.
目的：通过对坐骨神经损伤模型的药物实验研究，观察丙戊酸钠对大鼠周围神经损伤的修复作用。
Objective: to evaluate the efficacy and side effects of sodium valproate and carbamazepine in the treatment of manic episodes refractory to lithium carbonate.
目的：评价丙戊酸钠与卡马西平对锂盐治疗无效的躁狂发作的疗效和副反应。
CONCLUSION: This HPLC-fluorescence method is quick, sensitive and economical, which can be used to monitor the concentration of sodium valproate in human serum.
结论：本检测方法快速、灵敏、经济，可用于监测人血清中丙戊酸钠的浓度。
The levels of alanine aminotransferase(ALT) and aspartate aminotransferase(AST) in the serum of the rats administered sodium valproate alone were rasied significantly(P<0.05).
丙戊酸钠与五味子乙素联合应用，大鼠血清中天门冬氨酸转氨酶、谷丙转氨酶水平显著下降（P<0.05）。
Methods: Seizures in the group of epileptic rats induced by penicillin, the group of the LTG, and the group of the sodium valproate were measured, and the EEG was recorded for the groups.
方法：观察青霉素致痫组、拉莫三嗪组、丙戊酸钠组大鼠痫性发作，并记录其脑电图。
Conclusion Sodium valproate and phenytion sodium have the certain clinical efficacy in treatment of generalized tonic-clonic seizure. But phenytion sodium has the more and worse untoward reaction.
结论丙戊酸钠、苯妥英钠治疗癫痫全面性强直阵挛发作疗效肯定，但苯妥英钠不良反应多。
Results: After 1 week and 4 weeks treatment, the total scores of PANSS, scores of positive symptoms and psychopathology were significantly decreased in sodium valproate group than in controlled group.
结果：合用组治疗1周后及治疗结束时PANSS量表总分、阳性症状、精神病理症状的评分比单用组明显为低。
The risk of developing a rash is higher if taking lamotrigine while also taking valproate or divalproex sodium or if taking a higher starting dose or increasing the dose faster than prescribed.
如果使用拉莫三嗪的同时使用了丙戊酸钠或双丙戊酸钠，或者采用了更高的起始剂量，或是增加剂量速度过快都有可能增加发生皮疹的风险。
As a first - line agent for treating epilepsy, valproate sodium is widely used in clinic.
丙戊酸钠作为常用一线抗癫痫药，目前在临床的应用较为广泛。
As a first - line agent for treating epilepsy, valproate sodium is widely used in clinic.
丙戊酸钠作为常用一线抗癫痫药，目前在临床的应用较为广泛。
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