CONCLUSION: the synthetic method of sodium taurocholate is acceptable.
结论：合成法制备牛磺胆酸钠结果令人满意。
OBJECTIVE: To synthesize sodium taurocholate and study its pharmacological effects.
目的：化学合成牛磺胆酸钠，并对其药理作用进行研究。
Methods Retrograde pancreatic duct injection of 5% sodium taurocholate to establish ANP models.
方法逆行胰管注射5%的牛磺胆酸钠溶液制作ANP模型。
Methods SAP model was induced by retrograde injection of 5% sodium taurocholate into pancreatic duct.
方法：逆行胰胆管注射5%牛磺胆酸钠制作SAP模型。
Methods The rat model of ANP was established by retrograde bile-pancreatic duct injection of 5% sodium taurocholate.
方法逆行胆胰管注射5 %牛磺胆酸钠溶液制成ANP模型。
Methods The model of ANP was established in 90 rats by retrograde injection of 5% sodium taurocholate into biliopancreatic duct.
方法采用5%牛磺胆酸钠逆行胆胰管注射建立大鼠ANP肝损害模型，90只大鼠，随机分成三组。
Methods a model of experimental PE in AHNP was induced by retrograde injection of 5 % sodium taurocholate into the pancreatic duct.
方法应用5%牛磺胆酸钠逆行胰胆管注射诱发大鼠ahnp并发脑组织损害模型。
RESULTS: the yield of synthetic product, the infrared spectrum of which was conformable to the chemical structure of sodium taurocholate, was over 50%.
结果：合成法制备牛磺胆酸钠收率在50%以上，其红外光谱与结构相符。
METHODS: Antitussive test, expectorant test and antiasthmatic test were made with sodium taurocholate prepared by conjugating starting compound cholic acid with taurine.
方法：以胆酸为起始物，结合牛磺酸制备牛磺胆酸钠，并对其进行镇咳、祛痰和平喘实验。
Methods: Acute pancreatitis model was induced by intraperitoneal injection of cerulein or retrograde infusion of 5% sodium taurocholate into the bilipancreatic duct in SD rats.
方法： 分别采用腹腔注射雨蛙肽和胆胰管逆行注射5%牛磺胆酸钠建立大鼠轻症、重症急性胰腺炎模型。
Methods: A model of experimental PCH induced acute hemorrhagic necrotizing pancreatitis(AHNP) was induced by retrograde injection of 5% sodium taurocholate into the pancreatic duct.
方法：应用5 %牛磺胆酸钠逆行胰胆管注射诱发大鼠AHNP并发脑组织损害模型。
Methods: A model of experimental PCH induced acute hemorrhagic necrotizing pancreatitis(AHNP) was induced by retrograde injection of 5% sodium taurocholate into the pancreatic duct.
方法：应用5 %牛磺胆酸钠逆行胰胆管注射诱发大鼠AHNP并发脑组织损害模型。
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