Therefore, SIRT1 may be emphasized as a new therapy target for many different diseases.
因此，SIRT1可作为治疗不同疾病的靶点逐渐被人们所重视。
Another member, human SIRT1 also plays a part in regulation of cell survival and metabolism.
人类SIRT1在细胞存活与代谢等过程中也起到调节作用。
Deacetylation of p53 occurs through interaction with the SIRT1 protein, a deacetylase that may be involved in cellular aging and the DNA damage response (19).
SIRT1蛋白，一种涉及到细胞衰老和DNA损伤反应的去乙酰基酶能够与p53结合，促使后者的去乙酰化（19）。
The reduced-calorie diet was also associated with increased of a protein known as SIRT1, which influences a variety of functions, including age-related diseases.
另外，热量较低的饮食还可以延长一种名叫SIRT1的蛋白质的寿命，该物质能够对人体器官的多种功能产生影响，其中包括抵抗与年龄有关的疾病。
Moreover, resveratrol influenced Sirt1 in a beneficial way and it also affected the secretion of adipokines, fat cells that engage in cell-to-cell communication.
此外，白藜芦醇影响了SIRT1的一个有益的方式，也影响了脂肪因子的分泌，在细胞与细胞之间交流沟通，脂肪细胞。
Results The positive rate of SIRT1 expression in gastric cardia carcinoma cases was significantly higher than that in normal gastric cardiac region tissues (P<0.01);
结果SIRT1在贲门癌中的阳性表达率高于正常贲门中的阳性表达率（P<0.01）；
Many scientists believe that the compound affects a variety of mechanisms in the body, including sirtuin enzymes such as SIRT1, which are involved in the aging process.
很多科学家相信这个化合物会影响人体一系列的功能，包括sirtuin酶，如和年龄有关的成为SIRT1的sirtuin酶。
In this review, we summarized the neuroprotective role of SIRT1 in AD and its possible molecular mechanisms, proposing a novel strategy for preventing and treating neurodegeneration.
本文结合近年的研究，重点总结了SIRT1在AD中的神经保护作用及其可能的分子机制，为防治神经退行性疾病提供新思路。
The researchers say that the results don't necessarily conflict with studies suggesting that SIRT1 is pro-tumor. Whether SIRT1 promotes or prevents cancer probably depends on the situation.
研究人员说这个结果不会与研究SIRT1是肿瘤前身发生冲突，SIRT1究竟是促进还是阻止肿瘤讲随着研究是深入而逐渐明朗。
The researchers say that the results don't necessarily conflict with studies suggesting that SIRT1 is pro-tumor. Whether SIRT1 promotes or prevents cancer probably depends on the situation.
研究人员说这个结果不会与研究SIRT1是肿瘤前身发生冲突，SIRT1究竟是促进还是阻止肿瘤讲随着研究是深入而逐渐明朗。
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