In experiments on mice, researchers tracked brain levels of cell-signaling protein molecules called cytokines, which are boosted by SSRIs, and found they were counteracted by anti-inflammatory drugs.
研究人员在白鼠上实验,追踪叫做细胞活素类的细胞信号传导蛋白的脑部水平(它受ssris的刺激),发现消炎药削弱了这些蛋白质的活动。
Dynamic protein phosphorylation is a key cellular signaling mechanism by which a broad spectrum of cellular processes is regulated.
动态的蛋白磷酸化是一种关键的细胞信号机制,参与调节广泛的细胞过程。
Calcium is a universal signaling molecule involved in many cellular functions such as cell motility, metabolism, protein modification, protein folding, and apoptosis.
钙是一种通用的信号传导分子,参与许多细胞功能,如细胞运动、代谢、蛋白质修饰、蛋白质折叠和细胞凋亡。
Activation of the FSH receptor is known to contribute to the signaling of vascular endothelial growth factor (VEGF), a protein that stimulates the growth of blood vessels, including those in tumors.
现已知fsh受体的激活可以促进血管内皮生长因子(VEGF)的信号传导通路,而VEGF可以促进包括肿瘤组织在内的血管的生长。
Specific signaling motifs include not only sequences that are recognized by protein kinases (1), but also those that are recognized by phosphorylation-dependent binding proteins such as 14-3-3 (2).
特异的信号基序不仅包括蛋白激酶可以识别的序列(1),也包括那些能够被磷酸化依赖结合蛋白如14-3-3识别的序列(2)。
These two tRNA synthetases link protein synthesis to a major cell signaling pathway in the given mammalian cells.
在哺乳动物细胞中,蛋白质的生物合成途径与细胞信号转导途径紧密相连。
Their functions were related to cell division, apoptosis, signaling, regulation of gene and protein expression, tissue or cell structure, metabolism and so on. Several genes were functionally unknown.
分别是细胞分裂、凋亡、信号传递、基因和蛋白质表达调控、组织细胞结构、物质和能量代谢相关的基因以及某些功能尚不清楚的基因。
Protein kinases and phosphatases play a central role in cellular signaling.
蛋白激酶与蛋白磷酸酶在细胞信号传递中起着重要作用。
Furthermore, GSH has ancillary functions, such as metabolism, cell signaling, and protein interactions, that can also mediate defense against oxidants.
此外,GSH在代谢、细胞信号传导和蛋白质间相互作用中也具有辅助性功能,还可调节机体防御反应。
In vertebrates, IRS-2 functions as a scaffolding protein to coordinate separate branches of the Insulin/IGF-signaling cascades (2).
在脊椎动物中,IRS-2以脚手架蛋白发挥作用,协调胰岛素/IGF信号级联通路中的不同分支(2)。
Regulator of G-Protein Signaling Subtype 4 Mediates Antihypertrophic Effect of Locally Secreted Natriuretic Peptides in the Heart.
蛋白信号亚单位4的调节因子介导心脏局部分泌钠尿肽的抗心肌肥厚效应。
The retrieved figures are ranked by a score representing the likelihood to be of a certain type, in this case, schematic illustrations of protein interactions and signaling events.
在这种情况下,检索到的图片通过表示成为一种特定类型(蛋白质相互作用和信号事件的图解插图)的可能性的一个分数被排序。
Objective:To study the effect of Chinese herb Vitality Reinforcing Formula on protein kinase activity of cellular signaling transduction system.
探讨中药固真方对细胞信号转导体系中蛋白激酶活性的影响。
What we are doing here is precisely matching a treatment to a specific type of cancer cell mutation and abnormal protein signaling pathways that may activate cancer cell growth.
我们在此所做的就是精确匹配治疗方案。一种治疗方案针对一种特殊类型的癌症突变细胞和可能激活癌症细胞生长的异常蛋白信号通路。
Death domains and death domain-like protein interaction motifs in many proteins may bind each other or to some adaptor proteins for signaling.
含有死亡结构域或类死亡结构域的蛋白可以相互或与某些蛋白作用,从而进行信号传导。
Protein phosphorylation has emerged as a ubiquitous regulatory switch in cell signaling networks.
蛋白磷酸化在控制细胞信号传导中无处不在。
Presumably, the abl protein, like the product of many other so-called housekeeping genes, is not essential in normal signaling pathways.
人们推测abl蛋白和其他许多看家基因的产物一样,对于正常的信号转导途径并不是必须的。
They found that all three signaling pathways work by inactivating a protein known as BAD that causes cell death.
他们发现这三种信号通路能灭活一种已知的能导致细胞死亡的BAD蛋白。
Research of biochemistry and pharmacology in medicine showed that a lot of medicines play their role through G protein coupled signaling pathways.
在有关生化及药理的医学研究中发现许多药剂都是通过G蛋白偶联信号传导途径对动物起作用的。
Electively targeting of signaling pathways using protein kinase inhibitors would have a potential advantage over receptor blockers.
这种用来选择性地阻断信号转导途径的蛋白激酶抑制剂可能是一种潜在的有利的受体阻断剂。
To investigate the change of mitogen activated protein kinase(MAPK) signaling pathway during prostate cancer progression, and therefore to explore its role on cell proliferation.
目的:研究前列腺癌进展中细胞丝裂原活化蛋白激酶(MAPK)信号通路的变化,探讨阻断此通路对前列腺癌细胞增殖的影响。
Abstract: Recent studies showed that the essential amino acids not only functioned as the substrates of milk protein synthesis, but also as the signaling molecules to regulate milk protein synthesis.
摘要:最近的研究表明,必需氨基酸不仅可以作为合成乳蛋白的底物,还可以作为信号分子调控乳蛋白的合成。
Abstract: Recent studies showed that the essential amino acids not only functioned as the substrates of milk protein synthesis, but also as the signaling molecules to regulate milk protein synthesis.
摘要最近的研究表明,必需氨基酸不仅可以作为合成乳蛋白的底物,还可以作为信号分子调控乳蛋白的合成。
He thinks the protein may be a link between energy production and calcium signaling in the heart cell - a crucial part of the process that makes the heart beat.
他认为这种蛋白质能够将能量与钙离子通道连接起来,这也是心脏跳动中最重要的一部分。
G protein coupled signal transduction system is one major transmembrane signaling pathways in cell.
蛋白偶联信号传导系统是一类重要的细胞跨膜信号传导途径之一。
JAK2 is a constitutive protein tyrosine kinase (PTK) which can activate JAK-STAT signaling.
JAK2是一种组成性酪氨酸激酶,能激活JAK - STAT信号传导途径。
Studies on interactions of protein-protein or transcription will be important to understand the function and constitute of signaling pathway, and the native characteristics of life.
研究信号转导途径中蛋白与蛋白之间或者转录因子之间相互作用对于掌握调控机制和分子组成以及揭示生命活动现象的本质有重要意义。
In particular, the new findings suggest that the protein complex decommissions receptors that respond to pro-growth signals coming from the well-studied BMP signaling pathway.
尤其是,新的发现提示该蛋白质复合物使响应来自倍受研究的骨形态发生蛋白信号途径(BMP signaling pathway)的有利于突触生长的信号的受体解除任务。
In particular, the new findings suggest that the protein complex decommissions receptors that respond to pro-growth signals coming from the well-studied BMP signaling pathway.
尤其是,新的发现提示该蛋白质复合物使响应来自倍受研究的骨形态发生蛋白信号途径(BMP signaling pathway)的有利于突触生长的信号的受体解除任务。
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