For example, tumor cells can signal nearby blood vessels to grow in their direction, thereby facilitating tumor growth.
肿瘤细胞可以向血管发出信号让血管靠肿瘤方向伸长,从而有利于肿瘤的成长。
Tumor is a kind of gene disease in the field of molecular biology, canceration is correlated with signal transduction system, regulate of cell cycle, differentiation and development of cell apoptosis.
肿瘤是一种基因疾病,在当前分子生物学领域中,细胞癌变与细胞信号传导系统、细胞周期调控、细胞的生长和分化,以及细胞凋亡等均有关联。
In some cases, a decrease in a patient's symptoms may signal whether or not the medications are shrinking the tumor.
在某些情况下,无论药物能否缩小肿瘤,只要能使患者的症状缓解也是一种信号。
According to the anatomic site, tumor lesion character, and MRI signal, the majority of cerebellopontine angle area tumors were diagnosed accurately.
根据解剖部位、肿瘤病变特征和MR信号特点,能对大多数桥小脑区肿瘤进行定性诊断。
In combination with signal intensity and morphologic features, MRI is more useful and, therefore, superior to CT in differentiation of malignant from benign pleural tumor.
但当MR信号与形态学特点结合时,其对良、恶性胸膜肿瘤的鉴别诊断价值则明显优于CT。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
This article reviews its role in the signal transduction, expression and regulation in tumors and the roles in tumor metastasis.
本文对骨桥蛋白在肿瘤中的信号转导、基因表达与调控以及肿瘤转移过程中的作用予以综述。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂,能阻断酪氨酸蛋白激酶信号传导通路,从而促进肿瘤细胞凋亡。
Color Doppler imaging suggested red blood flow signal of central retinal artery (CRA) branched into tumor.
彩色多普勒表现视网膜中央动脉(CRA)红色血流信号进入肿瘤内呈分支状。
CONCLUSION: CD117 can be regard as the related tumor antigen of MM, and may be a valuable marker in the use of tyrosine kinase selective inhibitors, which inhibit the signal conduct to the target.
结论CD 117可作为MM的肿瘤相关抗原,也可作为靶向信号转导抑制剂酪氨酸激酶选择性抑制剂应用的有价值的标志。
Objective: To analyse comparatively the relationship between the MRI signal characteristics of adrenal tumor and their pathologic types.
目的:分析肾上腺肿瘤的MRI信号特征与病理类型间的关系。
Results: The chief characteristics of chordoma in low field MRI were: tumor signal change, tumor shape transformation, bone destruction, the perivascular erosion , etc.
结果:脊索瘤的低场MRI的主要表现有:肿瘤信号变化,肿瘤形态改变,骨质破坏,周围血管侵蚀及肿瘤外周侵犯等。
The mechanism of tumor dormancy is related to hindrance of angiogenesis, oncogene and antioncogene, immunocompetence, proliferation cycle, signal conduction and so on.
其发生机制可能与肿瘤血管生成受阻、癌基因与抑癌基因、宿主免疫状态、肿瘤细胞增殖周期及信号传导有关。
Conclusions: Kanglaite Injection can inhibit tumor angiopoiesis, its mechanism and regulate related to VEGF/VEGFR-2 signal conduct.
结论:康莱特能在一定程度上抑制肿瘤血管生成,其作用机制与调控VEGF/VEGFR-2信号传导有关。
This gene is missing in SCC tumor cells and, as it turns out, provides the signal for cells to stop multiplying.
事实证明,SCC肿瘤细胞中缺失的这个基因能够能发出信号阻断肿瘤细胞增生。
CONCLUSION: NGX6 transfection leads to molecular changes of some important signal pathways, and may suppress cell proliferation and metastasis of tumor by regulating these signal pathways.
结论:NGX6转染引起了一些非常重要的信号转导通路上的分子改变,可能通过参与调节这些信号转导通路而发挥其抗肿瘤增殖和转移的作用。
Those genes with increased expression level in aging lung mainly related to cytoskeleton or extracellular matrix, inflammation or stress response, tumor, signal transduction and so on.
上调为主的有:细胞骨架和胞外基质、炎性应激反应、肿瘤相关、信号转导等;
Whole body images showed the high signal intensity in tumor and liver.
全身成像显示了在肿瘤和肝脏的高信号强度。
With the thorough research of tumor mechanism, drugs acting on cell signal transduction pathway began to attract attention of researchers as an important target for anticancer drug development.
随着对肿瘤发生机制研究的深入,作用于细胞信号转导通路的药物开始引起研究者的关注,成为抗肿瘤药物研发的重要靶点之一。
Conclusion: MR signal intensities of HCC reflect histologic type of the tumor and nuclear DNA content to a certain degree.
结论:HCC的磁共振信号改变一定程度上反映了不同的组织学类型及DNA含量的高低。
To investigate the expression of extracellular signal-regulated kinase (ERK) and its significance in epithelial ovarian tumor.
探讨细胞外信号调节激酶(ERK)在卵巢上皮性肿瘤组织中的表达及其意义。
"If the PSA level starts rising while a man is on this drug, that is a very strong signal that he has an aggressive tumor" and needs a biopsy, Andriole said.
“如果服用该药的男性PS A值开始上升,这是一个很强的患上侵润肿瘤的信号”且需要进行活检,Andriole说。
Using molecular cell biology, biochemistry, genetics and other approaches to study the signal transduction pathways in cancers and establish tumor targeting strategy for drug development.
用分子细胞生物学、生物化学、遗传学等手段研究肿瘤细胞内的信号传导通路与肿瘤发生机理;筛选肿瘤治疗特异性靶标与新药开发。
STAT3 may become a new cancer treatment target. Blocking STAT3 signal may reduce tumor cell invasion and metastasis, and inhibit tumor cell grow, which can provide a new idea for cancer treatment.
STAT 3有可能成为肿瘤治疗中一个新的治疗靶位,阻断STAT 3信号传导通路可能降低肿瘤细胞的侵袭和转移、抑制肿瘤细胞生长,可为肿瘤治疗提供新的思路。
"The cell signal factor SCAI controls the formation and function of b1-integrin," says Dr. Robert Grosse. "If there is too little SCAI in tumor cells, then b1-integrin is overactive, so to speak."
RobertGrosse博士说:“细胞信号因子scai控制b1 -整联蛋白的形成和功能,可以说,如果肿瘤细胞中scai太少,b1 -整联蛋白就会表现得过度活跃。”
The results suggest that macrophages in several of transplantation tumor lesions and changes of SPIO-enhanced MRI signal can be used as the method of evaluating the tumor immunological responses.
少数纯瘤株移植瘤结节内见巨噬细胞是肿瘤免疫应答的结果,SPIO增强MRI信号变化可作为评价肿瘤免疫的方法。
The discovery of oncogenes and tumor suppressor genes, and the research of signal transduction pathway yield profound insights into the mechanisms of carcinogenesis.
癌基因和抑癌基因的发现,细胞信号传导通路的阐明,极大地丰富了人们对细胞癌变机制的认识。
The mechanism are antioxidation, cell proliferation suppression, apoptosis induction, cell signal transduction disturbing and tumor suppression gene activity enhancing, cell cycle disturbing etc.
其作用机理为抗氧化作用,抗细胞增殖,诱导细胞调亡,干预细胞转导和增强抑癌基因表达,干预细胞周期等。
The mechanism are antioxidation, cell proliferation suppression, apoptosis induction, cell signal transduction disturbing and tumor suppression gene activity enhancing, cell cycle disturbing etc.
其作用机理为抗氧化作用,抗细胞增殖,诱导细胞调亡,干预细胞转导和增强抑癌基因表达,干预细胞周期等。
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