If the self tolerance is broken or blocked by some reasons, autoimmunity and some diseases might occur.
若自身耐受因某些原因遭到破坏或中止时，就可能发生自身免疫反应或自身免疫病。
Immunoregulation mediated by regulatory t cell is one of the most important mechanisms to maintain self tolerance.
调节性T细胞介导的免疫调节是自身耐受的重要机制之一。
Recently, accumulating evidences have shown that regulatory t cells play a key role both in maintenance of self tolerance and tolerance to allograft.
近年来，调节性T细胞在自身耐受和抑制同种异体排斥反应中的作用受到越来越多的重视。
Activation of this process in immature T cell by the bindng of the TCR CD3 to self antigens may therefor be the mechanism which produces clonal deletion and consequently self tolerance.
未成熟T细胞通过TCR-CD3 复合物与自身抗原接合激活上述过程可能与克隆清除的形成机制及自我耐受有关。
Objective To detect the relationship between the promiscuous gene expression in thymus and the diseases of self-tolerance and self-reaction.
目的探讨胸腺异位基因表达与自身耐受及自身免疫病的相互关系。
Understanding the mechanisms of self-tolerance will help to find new strategies for treatment of autoimmune disease, hypersensitivity, transplantation rejection and tumor.
对自身免疫耐受产生机制的揭示将为自身免疫病、超敏反应、移植排斥及肿瘤的治疗提供新的策略。
Understanding the mechanisms of self-tolerance will help to find new strategies for treatment of autoimmune disease, hypersensitivity, transplantation rejection and tumor.
对自身免疫耐受产生机制的揭示将为自身免疫病、超敏反应、移植排斥及肿瘤的治疗提供新的策略。
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