Objective to explore the antitumor mechanisms of mifepristone (RU486).
目的探讨米非司酮(RU486)抗肿瘤作用的机制。
RU486, an antagonist of glucocorticoid receptor (GR), did not affect these effects.
这些作用不能被糖皮质激素受体(GR)拮抗剂ru 486所阻断。
This study presents the effects of RU486 on human chorio-trophoblast and decidual cells.
本文报道RU 486对离体人绒毛膜滋养层、蜕膜细胞的影响。
On the contrary, RU486. a progesterone antagonist. caused significant inhibition of cell growth.
孕激素拮抗剂RU486有明显的抑制肿瘤生长作用。
Objective to investigate the pregnancy rate after treatment of ectopic pregnancy with the mifepristone (RU486).
目的探讨米非司酮(RU4 86)治疗异位妊娠成功后的宫内再孕率。
There was a significantly different response of pituitary adrenal axis to RU486 between normal subjects and Cushing's group.
正常人和库欣综合征患者的垂体肾上腺轴对RU486有明显不同的反应。
Conclusion RU486 has antitumor effect, but has different antitumor mechanism between steroid hormone receptor positive and negative breast cancer cell lines.
结论RU486具有抗肿瘤作用，对不同类固醇激素受体状态的乳腺癌细胞其抗肿瘤作用的机制不同。
Although RU486 is progesterone antagonist in receptor level, no apoptotic cell death was found in the trophoblastic cells. According to referred data, only degeneration or necrosis t...
虽然RU486可在受体水平拮抗孕酮，但在滋养细胞及在脱膜细胞均无凋亡现象发生。
Although RU486 is progesterone antagonist in receptor level, no apoptotic cell death was found in the trophoblastic cells. According to referred data, only degeneration or necrosis t...
虽然RU486可在受体水平拮抗孕酮，但在滋养细胞及在脱膜细胞均无凋亡现象发生。
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