In this project we are screening the kingdom of life for the presence of ribozymes.
在该项目中，我们试图筛选出各种存在的核酶。
We also include artificially designed ribozymes in order to find out whether natural analogs exist.
我们同时包含了人工设计的一些核酶，以便找出是否存在天然的同型物。
Dr Szostak has already made a range of "ribozymes", as catalytic pieces of RNA are known in the trade, and some of them are ATP-powered.
萧斯泰克已经做出了一系列的“核酶”，因为已知有催化效用的RNA在发挥作用，而且有一些需要AT P提供能量。
Thus, any random changes in the interior, fledgling ribozymes that could speed up nucleic acid replication rates will spread rapidly through an evolving population.
这样一来，细胞内部发生的使得核酶加速核酸复制速率的任何变化，都会在进化群体中快速扩散。
Its catalytic repertoire expanded by modification and in-vitro-selection of nucleic acid libraries endows ribozymes a great potential as gene therapeutic agents and nucleic acid probes.
对天然核酶的改造和人工核酶的筛选使核酶的催化反应谱得到了扩展，也为核酶作为基因治疗药物和核酸探针提供了多种选择。
Some investigations on the ciliated protozoan have provided the insights into the mechanism of ribozymes, self-splicing RNA, telomere structure and function, DNA sequence reorganization and so on.
通过对它的研究，人们发现并且掌握了核酶的分子机制、RNA的自我拼接、端粒的结构和功能、DNA序列重组等机理。
With appropriate designing, it could block oncogene's expression, reverse MDR, and promote tumor cell apoptosis. All these properties make the Ribozymes as potentially useful regent for gene therapy.
设计合适的核酶分子能够阻断癌基因的异常表达，逆转肿瘤细胞MDR，促进肿瘤细胞凋亡，有望成为肿瘤基因治疗的有效手段之一。
With appropriate designing, it could block oncogene's expression, reverse MDR, and promote tumor cell apoptosis. All these properties make the Ribozymes as potentially useful regent for gene therapy.
设计合适的核酶分子能够阻断癌基因的异常表达，逆转肿瘤细胞MDR，促进肿瘤细胞凋亡，有望成为肿瘤基因治疗的有效手段之一。
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