The researchers built on fundamental discoveries on the structure and replication of DNA made by Nobel laureates James Watson, Francis Crick and Arthur Kornberg.
研究人员希望继诺贝尔奖获得者詹姆士。华特森,弗朗西斯。科里克,亚瑟。科恩伯格之后在DNA的结构和复制领域有所重大发现。
Antisense RNA exists in all kinds of living beings wildly. It ACTS on the course of the replication of DNA, transcription and translation, which realize the regulation and control of gene expression.
反义rna广泛存在于各类生物中,它作用于DNA的复制、转录、转译的过程,实现对基因表达的调控。
Szostak said: "When we started the work, we were really just interested in the very basic question about DNA replication, how the ends of chromosomes are maintained."
绍斯塔克说:“当我们着手这项研究时,我们真的只是对有关DNA复制的基本原理及如何维护染色体末端感兴趣。”
In this way, studying the efficacy of DNA damage response inhibitors on HBV infection and replication was available.
通过这种方式,研究DNA损伤反应抑制剂对于HBV感染和复制的作用成为可能。
The structure of DNA and its functions of replication and transcription are compatible.
DNA的结构与它所担负的复制和转录的功能是协调一致的。
At the end of the experiment, a little girl told me, "Apart from the fact that improper replication of the DNA molecule causes genetic disease, we have understood nothing else."
实验结束时,一个小女孩告诉我,“除了知道不恰当复制DNA分子会引起基因疾病这一事实外,其它的就不理解了。”
He added that if the DNA on multiple mitochondrial chromosomes is replicating in concert, replication of the entire mitochondrial genome would occur faster.
他补充说,如果多线粒体染色体上的DNA同时复制,那么复制整个线粒体基因组将更快。
The research team led by Professor, Zhong from Beijing Institute of Biotechnology used report that HBV infection activates and exploits the DNA damage response to replication stress.
该研究小组的负责人钟教授来自北京生物技术学院,他曾经报道过HBV感染可以激活并利用DNA损伤修复机制来应对复制的压力。
The enzymes that replicate DNA when a cell divides are not 100% efficient, and a small amount of DNA gets lost from the end of each strand during replication.
复制DNA的酶在细胞分裂时不是100%有效,少量dna在复制过程中从每一串的端部丢失。
What is the function of ligase in DNA replication?
什么是连接酶的作用在脱氧核糖核酸复制的?
Proliferating cell nuclear antigen (PCNA) is the kernel component of replication complex of eukaryotic organism, and needed for DNA synthesis.
增殖细胞核抗原(pcna)是真核生物复制复合体的核心成分,为DNA合成所必需。
This research will facilitate to find new DNA-binding protein, and it is important to reveal the molecular mechanisms of DNA replication and transcription and DNA repair and recombination.
该研究对于寻找新的DNA结合蛋白,研究生物体中遗传信息的复制、转录、修复和重组的分子生物学机制具有重要意义。
Objective to investigate the relationships between skin photoaging and point mutations in mitochondrial DNA (mtDNA) control region for replication of dermal fibroblast.
目的探讨皮肤光老化与真皮成纤维细胞线粒体DNA复制控制区点突变的关系。
The fidelity of DNA replication in prokaryotes is discussed in this paper.
本文概述了促成原核生物DNA复制准确性的因素。
The packaging of eukaryotic DNA into chromatin influences various processes that utilize DNA as a template, including transcription, replication and repair.
真核生物dna紧密包装成染色质结构,影响了包括转录、复制和修复等在内的以dna为模板的每一个生物过程。
During the replication and transcription, DNA unwinds the double helix under the control of an enzyme. It is a very complex process beyond a physical description.
DNA双螺旋链在复制和转录的过程中要在酶的催化下解旋,这是一个高度复杂的过程,目前还无法用物理学的方法来描述。
Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.
结论苯中毒患者外周血白细胞的DNA复制及损伤修复基因与正常人相比存在差异性表达,为进一步筛选苯中毒生物标志物提供了依据。
DNA mismatch repair system could recognize and repair mistakes in process of DNA replication, guard stability and integrality of genome.
DNA错配修复系统可以识别并纠正DNA复制过程中出现的错误,保证基因组的稳定性和完整性。
The full collection of DNA polymerase III subunit. Necessary for replication to occur with high processivity.
DNA聚合酶III的完整亚基组合。是持续进行复制所必需的。
Proteins that bind to single-strands of DNA at a replication fork, protecting the strands and preventing them from rebinding to each other.
在复制叉处与单链dna结合的蛋白质,它们保护单链防止它们互相重新结合。
Objective To investigate the association of polymorphisms of CDT1 and GMNN gene, two important genes participating in DNA replication, with the risk of sporadic breast cancer.
目的探讨参与DNA复制的两个重要基因CDT1和GMNN基因多态性与我国人群散发乳腺癌的关联。
DNA helicases are essential for replication of baculoviruses.
杆状病毒DNA解旋酶是病毒复制所必需的。
An enzyme responsible for extending the parent strand of DNA at the telomere during replication so that telomeres can be fully replicated.
在复制过程中负责延伸端粒处DNA亲本链的酶,可使端粒复制完整。
The main function of telomerase is for the replication of telomere DNA, which is closely related with tumor and cell senescence.
端粒酶的主要功能是复制端粒末端dna,维持端粒长度。端粒酶活性调节与肿瘤发生和细胞衰老有着密切关系。
The inhibitive effect of prodigiosin on multiplication of cancer cells was related to the inhibiting of DNA replication in S stage and regulating of cell cycle.
研究表明灵菌红素抑制细胞的增殖,与抑制S期细胞的DNA复制及调控细胞的增殖周期相关。 同时,细胞凋亡的产生与实验药物呈正相关。
Recently, replication protein a (RPA) has become one of the main areas in the study of cellular responses to DNA damage.
复制蛋白a (RPA)是目前国内外研究细胞DNA损伤应激反应的热点之一。
Objective To acknowledge the existence and replication of TTV DNA in peripheral blood mononuclear cells(PBMC) of patients with serum TTV DNA positive.
目的了解TTV阳性肝炎患者外周血单个核细胞(PBMC)TTVDNA存在及复制情况。
In vitro DNA replication system derived from eukaryotes is capable of replicating exogenous plasmid DNA containing SV40 origin of replication efficiently and accurately.
报道了含sv40复制起点的质粒dna在真核细胞抽提物中进行复制的DNA体外复制系统的建立。
NS2 protein as a non-structural protein mainly involved in viral DNA replication and regulation of gene expression.
NS2蛋白作为非结构蛋白,主要参与病毒DNA的复制及调节基因的表达。
Many studies show that 4-oxo-dihydroquinolines have good oral bioavailability and plasma clearance, and they suppress both the DNA polymerase of HSV and virus replication in the cells.
多项研究表明,4 -氧代二氢喹啉类有良好的口服利用率及中等程度的血浆清除率,不仅对核苷酸聚合酶产生抑制,还可以抑制细胞内的病毒复制。
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