• Conclusion Adopting fusion protein P53 (PTD-P53) to treat lung cancer would be available.

    结论采用PTD -P 53治疗肺癌会是一种有效的途径。

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  • They found that the p53 gene makes not only the well-established p53 protein, but also an alternative "control switch" variation of the p53 protein - known as an isoform.

    他们发现p53基因不仅产生大家熟知p53蛋白质同时产生一种p53蛋白质变换“控制开关变种——对碘氧基苯甲醚。

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  • It is suggested that the overexpression of P53 protein may be an early event in carcinogenesis of the esophagus.

    结果表明P 53基因蛋白产物高表达食管癌的发生中一个早期生物学标志。

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  • Objective: to study the histological features and expression of P53 protein of lung cancer in aged patients.

    目的研究老年肺癌组织学特点及其P 53蛋白表达

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  • Objective: To analyse the significance and relationship between p53 gene mutation and the expression of mutant type p53 gene protein in the laryngeal carcinomas.

    目的探讨喉癌P53基因突变突变性P 53基因蛋白表达之间相互关系意义

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  • Objective to investigate the expression of MDM2 and P53 protein in osteosarcoma and its relation to the clinical-pathological parameters and prognosis of the tumor.

    目的探讨肉瘤mdm2P 53蛋白定位,表达水平,二者相互关系及其骨肉瘤转移预后影响。

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  • The expression of P53 protein was associated with the degree of differentiation, but not with the tumor locus and metastasis.

    P53蛋白在胆管癌表达升高,表达胆管癌分化程度有关肿瘤部位有无转移无关。

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  • OBJECTIVE: Purpose to study the expression of P53 mutation protein, estrin receptor (er) and progestin receptor (pr) in mammary cancer and their relativity.

    目的探讨乳腺癌P 5 3蛋白雌激素受体(ER),孕激素受体(PR)表达相关性研究。

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  • But during the wound repairing, much less expression of PCNA and P53 protein in diabetic skin tissue compared with non-diabetic skin tissue.

    创面组织修复过程中,糖尿病创面增殖细胞核抗原P 53蛋白表达明显少于糖尿病创面。

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  • Objective: the relationship between molecular margin represented by P53 protein and traditional cell pathological margin, the security and reliability to section 5.

    目的:探讨P 53蛋白为代表分子常规细胞病理切缘的关系以及切除肿瘤各边缘5

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  • Conclusion: the peritumoral edema on MRI in supratentorial astrocytic gliomas can reflect the positive expression rate of P53 protein.

    结论幕上星形细胞瘤瘤周水肿MRI表现反映肿瘤组织P 53蛋白表达程度

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  • The expression of mutation P53 protein was related closely to histopathologic grade, tumor size, metastasis and prognosis of tumor(P<0.05), but it was not related to histologic types(P>0.05).

    P53蛋白阳性表达组织学分级肿瘤预后复发肿瘤大小关系密切(P<0.05),组织学类型无相关性(P>0.05)。

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  • Conclusion Downregulation of CGRP on the expression of P53 protein in ischemic neurons might promote the recovery of the ischemia neurons.

    结论CGRP下调缺血神经元p 53蛋白表达可能缺血神经元的恢复促进作用

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  • Conclusion: P53 protein can be used in early clinical diagnosis. Early in gastric carcinogenesis, its change occurs at intestinal metaplasia stage.

    结论p 53蛋白胃癌早期诊断中起作用,改变在胃癌发生的早期即居于化生阶段的癌前变化过程中。

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  • The protein(P53) encoded by mutant p53 gene (mtp53) not only losses these functions, but also make cell malignant transformation.

    突变p53基因编码蛋白不但丧失上述功能甚至出现了促使细胞癌变的作用。

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  • Objective To explore the expression of CD105 protein in esophageal squamous cell carcinoma and it's relationship with P53 protein.

    目的探讨CD 105蛋白食管鳞状细胞(鳞癌)组织中的表达,及其P 53蛋白表达关系

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  • These results indicate that progression of enzootic bovine leucosis is closely related to expression of P53 protein in tumorous tissues.

    提示,流行性白血病发生与肿瘤组织P 53蛋白表达有重要关系

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  • Objective: To study the relationship between smoking and P53 protein expression in oral tumor tissue.

    目的:研究吸烟口腔肿瘤组织P53蛋白表达关系探讨吸烟致口腔癌的发病机制。

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  • Conclusion: P53 protein significantly inhibits telomerase activity in human keloid fibroblasts.

    结论P 53蛋白能够抑制瘢痕疙瘩成纤维细胞端粒酶活性

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  • The P53 protein may act as the marker determining biological behaviors of gastric cancer.

    P53蛋白作为判断胃癌生物学行为指标

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  • No correlation was found between the P53 protein overexpression and the clinical stages, neck lymph node metastasis, local recurrence and, survival of LSCC.

    P 53蛋白表达喉癌临床分期、分型、颈淋巴转移局部复发及预后相关性

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  • P53 protein expression was studied with immunohistochemically in 15normal oral mucosas, 45 precancerous lesions and 21 invasive squamous cell carcinomas.

    免疫组化技术检测了15正常口腔粘膜45病变21例浸润性标本的P53蛋白表达

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  • Objective: To study on the correlation between proliferating cell nucleus antigen (PCNA) and P53 protein expressions in ovarian epithelial tumors.

    目的研究卵巢上皮性肿瘤中pcnaP 53蛋白表达相关性

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  • Conclusion: (1) P53 Protein detection, VEGF expression and IMVD can be Considered as a biological indicator of malignant Potential in tongue cancer.

    结论:(1)P 53VEGF表达以及IMVD的测定可作为判断恶性潜能重要生物学指标

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  • The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.

    基因p53编码转录因子p53蛋白调控基因表达dna合成损伤修复以及细胞凋亡中关键作用

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  • Objective To explore the significance of P53 protein expression in different type of thymoma.

    目的探讨p53表达不同类型胸腺瘤中的意义

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  • Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).

    乙酰化似乎对于应激反应p 53蛋白累积正向作用(17)。

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  • Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).

    压力应激反应乙酰能够发挥促进p 53蛋白富集作用(17)。

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  • Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser15 of mouse p53 protein.

    单克隆抗体合成免疫动物产生,该肽段小鼠p 53蛋白15丝氨酸及其邻近氨基酸基序列一致。

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  • Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser15 of human p53 protein.

    该单克隆抗体合成的人源针对p 53蛋白丝氨酸(15位)的磷酸化肽段免疫动物生产的。

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