Conclusion Adopting fusion protein P53 (PTD-P53) to treat lung cancer would be available.
结论采用PTD -P 53治疗肺癌将会是一种有效的途径。
They found that the p53 gene makes not only the well-established p53 protein, but also an alternative "control switch" variation of the p53 protein - known as an isoform.
他们发现p53基因不仅产生大家熟知的p53蛋白质,同时还产生一种p53蛋白质变换“控制开关”的变种——对碘氧基苯甲醚。
It is suggested that the overexpression of P53 protein may be an early event in carcinogenesis of the esophagus.
结果表明:P 53基因蛋白产物的高表达在食管癌的发生中是一个早期生物学标志。
Objective: to study the histological features and expression of P53 protein of lung cancer in aged patients.
目的:研究老年肺癌组织学特点及其P 53蛋白的表达。
Objective: To analyse the significance and relationship between p53 gene mutation and the expression of mutant type p53 gene protein in the laryngeal carcinomas.
目的:探讨喉癌P53基因突变与突变性P 53基因蛋白表达之间的相互关系及意义。
Objective to investigate the expression of MDM2 and P53 protein in osteosarcoma and its relation to the clinical-pathological parameters and prognosis of the tumor.
目的探讨骨肉瘤mdm2和P 53蛋白定位,表达水平,二者的相互关系及其对骨肉瘤转移及预后的影响。
The expression of P53 protein was associated with the degree of differentiation, but not with the tumor locus and metastasis.
P53蛋白在胆管癌中表达升高,其表达与胆管癌的分化程度有关而与肿瘤部位及有无转移无关。
OBJECTIVE: Purpose to study the expression of P53 mutation protein, estrin receptor (er) and progestin receptor (pr) in mammary cancer and their relativity.
目的:探讨乳腺癌中P 5 3蛋白,雌激素受体(ER),孕激素受体(PR)的表达及相关性研究。
But during the wound repairing, much less expression of PCNA and P53 protein in diabetic skin tissue compared with non-diabetic skin tissue.
而在创面组织修复过程中,糖尿病创面增殖细胞核抗原,P 53蛋白表达明显少于非糖尿病创面。
Objective: the relationship between molecular margin represented by P53 protein and traditional cell pathological margin, the security and reliability to section 5.
目的:探讨了以P 53蛋白为代表的分子切缘与常规细胞病理切缘的关系以及切除肿瘤各边缘5。
Conclusion: the peritumoral edema on MRI in supratentorial astrocytic gliomas can reflect the positive expression rate of P53 protein.
结论:幕上星形细胞瘤瘤周水肿MRI表现反映了肿瘤组织P 53蛋白的表达程度。
The expression of mutation P53 protein was related closely to histopathologic grade, tumor size, metastasis and prognosis of tumor(P<0.05), but it was not related to histologic types(P>0.05).
P53蛋白的阳性表达与组织学分级、肿瘤预后复发及肿瘤大小关系密切(P<0.05),但与组织学类型无相关性(P>0.05)。
Conclusion Downregulation of CGRP on the expression of P53 protein in ischemic neurons might promote the recovery of the ischemia neurons.
结论CGRP下调缺血神经元p 53蛋白的表达,可能对缺血神经元的恢复有促进作用。
Conclusion: P53 protein can be used in early clinical diagnosis. Early in gastric carcinogenesis, its change occurs at intestinal metaplasia stage.
结论:p 53蛋白可在胃癌的早期诊断中起作用,其改变在胃癌发生的早期即居于肠化生阶段的癌前变化过程中。
The protein(P53) encoded by mutant p53 gene (mtp53) not only losses these functions, but also make cell malignant transformation.
突变型p53基因的编码蛋白不但丧失上述功能,甚至出现了促使细胞癌变的作用。
Objective To explore the expression of CD105 protein in esophageal squamous cell carcinoma and it's relationship with P53 protein.
目的探讨CD 105蛋白在食管鳞状细胞癌(鳞癌)组织中的表达,及其与P 53蛋白表达的关系。
These results indicate that progression of enzootic bovine leucosis is closely related to expression of P53 protein in tumorous tissues.
提示,流行性牛白血病的发生与肿瘤组织中P 53蛋白表达有重要关系。
Objective: To study the relationship between smoking and P53 protein expression in oral tumor tissue.
目的:研究吸烟与口腔肿瘤组织中P53蛋白表达的关系,探讨吸烟致口腔癌的发病机制。
Conclusion: P53 protein significantly inhibits telomerase activity in human keloid fibroblasts.
结论:P 53蛋白能够抑制人瘢痕疙瘩成纤维细胞端粒酶活性。
The P53 protein may act as the marker determining biological behaviors of gastric cancer.
P53蛋白可作为判断胃癌生物学行为的指标。
No correlation was found between the P53 protein overexpression and the clinical stages, neck lymph node metastasis, local recurrence and, survival of LSCC.
P 53蛋白表达与喉癌临床分期、分型、颈淋巴转移、局部复发及预后无相关性。
P53 protein expression was studied with immunohistochemically in 15normal oral mucosas, 45 precancerous lesions and 21 invasive squamous cell carcinomas.
用免疫组化技术检测了15例正常口腔粘膜、45例癌前病变和21例浸润性鳞癌标本的P53蛋白的表达。
Objective: To study on the correlation between proliferating cell nucleus antigen (PCNA) and P53 protein expressions in ovarian epithelial tumors.
目的:研究卵巢上皮性肿瘤中pcna和P 53蛋白表达的相关性。
Conclusion: (1) P53 Protein detection, VEGF expression and IMVD can be Considered as a biological indicator of malignant Potential in tongue cancer.
结论:(1)P 53、VEGF的表达以及IMVD的测定可作为判断舌癌恶性潜能的重要生物学指标。
The tumor suppressor gene p53 codes for a transcription factor, p53 protein, plays a critical regulation role in oncogene expression, DNA synthesis and repair systems, and cell apoptosis.
抑癌基因p53编码转录因子p53蛋白在调控癌基因表达、dna合成和损伤修复以及细胞凋亡中起关键作用。
Objective To explore the significance of P53 protein expression in different type of thymoma.
目的探讨p53的表达在不同类型胸腺瘤中的意义。
Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).
乙酰化似乎对于应激反应中p 53蛋白的累积起着正向的作用(17)。
Acetylation appears to play a positive role in the accumulation of p53 protein in stress response (17).
在压力应激反应中乙酰化能够发挥促进p 53蛋白富集的作用(17)。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser15 of mouse p53 protein.
单克隆抗体由合成肽段免疫动物产生,该肽段与小鼠p 53蛋白的15丝氨酸及其邻近氨基酸残基序列一致。
Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser15 of human p53 protein.
该单克隆抗体是由合成的人源的针对p 53蛋白丝氨酸(15位)的磷酸化肽段免疫动物生产的。
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