Cyclic AMP binds to the regulatory subunit of protein kinase A: Protein kinase A phosphorylates phosphorylase kinase.
环腺苷酸结合蛋白激酶的调节亚基：一个磷酸化蛋白激酶磷酸化酶激酶。
The gene IKKE produces a protein kinase also known as IKKE.
IKKE基因可以产生一种蛋白激酶，也被称作IKKE。
Objective To investigate the effects of increased protein kinase a (PKA) activity on the proliferation of T24 cell line and the possible mechanism.
目的探讨蛋白激酶A (pka)活性增高对膀胱癌细胞株t24增殖的影响及其机制。
AMP-activated protein kinase AMPK is a central component of a protein kinase cascade that plays a pivotal role in the regulation of intracellular energy status.
在调节细胞能量状态的蛋白激酶级联反应中，AMP激活的蛋白激酶（AMPK）是其中枢组成部分。
Objective:To observe the changes of the activity of protein kinase A(PKA) and C(PKC), and further investigate the mechanisms of anti-hypothermia action of Guizhi Tang.
目的：研究低体温大鼠下丘脑蛋白激酶A（PKA）、蛋白激酶C（PKC）活性的变化及桂枝汤的升温作用机理。
As a matter of fact, the compounds of the formula (I) are useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
事实上，式（I）化合物在疗法中可用于治 疗与失调的蛋白激酶活性相关的疾病例如癌症。
Here, we will review several kinds of protein kinases as potential targets for CVDs and some difficulty in identifying a protein kinase as a putative therapeutic target for CVDs.
在此，我们将总结一些已经能用于心血管疾病的蛋白激酶靶位，以及一些鉴定与心血管疾病有关蛋白激酶假定的治疗靶位的难点。
This gene, which encodes a protein kinase and is regulated by a small molecule called cyclic GMP, has been previously studied but not suspected to play a role in sleep regulation.
这个基因编码一种蛋白质激酶，并受环状GMP小分子的调节。该基因以前有过研究，但不知道它有一定的睡眠调节作用。
AIM: To examine possible direct effects of the vasodilators hydralazine and KRN2391 on the activities of protein kinase A (PKA) , protein kinase G (PKG), and protein kinase C (PKC).
目的：研究血管扩张药肼酞嗪和KRN2391对蛋白激酶的直接作用以探讨其作用机制。
Cerepro harnesses an adenovirus, a type of virus which carries its DNA in double-stranded form, to transmit a gene responsible for the production of a protein called thymidine kinase.
Cerepro被固定在一个腺病毒(一种能够携带双链形式的DNA病毒)上来传染基因，这个基因负责产生胸苷激酶这种蛋白质。
The latter encodes a novel protein kinase with LIM domains and is strongly expressed in the brain.
后者以LIM范围编码了一个新奇的蛋白质激酶，并且在大脑中强烈地表达。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
在小鼠模型中，GNA11突变诱导了自发转移性肿瘤，激活了丝裂原活化蛋白激酶途径。
Therefore, the aim of this study is to investigate the effects of genistein, a protein tyrosine kinase inhibitor, on acute and chronic inflammation in diabetic mice (induced by streptozotocin).
因此，本研究的目的是调查金雀异黄素，一种蛋白质酪氨酸激酶抑制剂，对有急性或慢性糖尿病炎症小鼠（诱导脲佐菌素）的影响。
It binds and activates protein kinase c, causing a wide range of effects in cells and tissues (1, 2).
它结合并激活蛋白激酶c，对很多细胞和组织产生影响(1,2)。
The recombinant human protein kinase CK2 may be used as a molecular target for simpler screening and development of more effective inhibitors of CK2.
重组人蛋白激酶CK2可作为一种较为简便筛选和开发有效的CK 2抑制剂的分子靶点。
Novel Oncogene with Kinase-domain (NOK) is a novel tumor-related gene, coding receptor like protein with a kinase domain.
是一个新的肿瘤相关基因，其结构上与受体蛋白相似，具有一个蛋白激酶结构域。
Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.
吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂，能阻断酪氨酸蛋白激酶信号传导通路，从而促进肿瘤细胞凋亡。
CONCLUSION (Kaempferol is a) novel potent inhibitor of protein kinase CK2 in vitro.
结论山萘黄素是一种新的体外蛋白激酶CK2的有效抑制剂。
The core of cell cycle regulation and control mechanism are relative to a group of protein kinase.
细胞周期调控机制的核心是一组蛋白激酶。
Electively targeting of signaling pathways using protein kinase inhibitors would have a potential advantage over receptor blockers.
这种用来选择性地阻断信号转导途径的蛋白激酶抑制剂可能是一种潜在的有利的受体阻断剂。
The tyrosine phosphorylated 130000 protein was identified as JAK2, a non receptor tyrosine kinase.
鉴定了分子量为130000酪氨酸磷酸化的蛋白质为JAK2，一种非受体型酪氨酸激酶。
Aurora A (AIK) is a cell cycle-regulated serine/threonine protein kinase that is overexpressed in many tumor cell lines (1-3).
极光激酶A（AIK）是一种调节细胞周期的丝氨酸/苏氨酸蛋白激酶，在多种肿瘤细胞系中过表达（1-3）。
CONCLUSIONS AG1109 not only was an effective inhibitor of protein tyrosine kinases, but also was a novel potent inhibitor of protein kinase CK2.
结论：AG110 9不仅是酪氨酸蛋白激酶的抑制剂，而且是一种十分有效的蛋白激酶CK2的抑制剂。
When the high-fat diet is fed to a normal mouse, IKKE protein-kinase levels rise, the metabolic rate slows, and the animal gains weight.
当给予正常的小鼠高脂饮食后，IKKE蛋白激酶水平上升，新陈代谢率降低，则小鼠会长胖。
Such lists can be projected onto prior knowledge of kinase-substrate interactions to infer the list of kinases associated with a specific protein list.
这些列表能够被投射到激酶-底物相互作用的先验知识，以推断与一个特定蛋白质列表相关的激酶列表。
The encoded proteins have a number of potential N-glycosylation as well as protein kinase recognition sites, which may be involved in the regulation of peptide transport;
被编码的蛋白上有多个N 糖基化和蛋白激酶的识别位点，它们可能参与肽转运的调控；
AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis (1).
腺苷酸激活的蛋白激酶(AMPK)是一种在酵母，植物和动物界高度保守的蛋白激酶，它在能量平衡中发挥关键性的作用(1)。
JAK2 is a constitutive protein tyrosine kinase (PTK) which can activate JAK-STAT signaling.
JAK2是一种组成性酪氨酸激酶，能激活JAK - STAT信号传导途径。
Thomas, PhD, of Lilly's Cancer Discovery Research division, ex- plained, "AKT1 is a protein kinase or enzyme that plays a key role in activating survival, proliferation and metabolic pathways."
Thomas博士解析道，“AKT1是一个蛋白激酶或酶，它在细胞生存、增殖及代谢通路的活化上起着重要作用。
Thomas, PhD, of Lilly's Cancer Discovery Research division, ex- plained, "AKT1 is a protein kinase or enzyme that plays a key role in activating survival, proliferation and metabolic pathways."
Thomas博士解析道，“AKT1是一个蛋白激酶或酶，它在细胞生存、增殖及代谢通路的活化上起着重要作用。
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