A general protein conformation searching and genetic algorithms are briefly introduced first.
首先,简要地介绍了遗传算法和一般的蛋白质构象搜索问题。
Fluorescence spectroscopy is an effective method of study on protein conformation in aqueous solution.
萤光光谱法是研究蛋白质在水溶液中分子构象的一种有效方法。
Proline-directed phosphorylation sites like this one are often targeted by CDKs and MAPKs and can often dramatically affect protein conformation (4,5).
类似这种的脯氨酸导向的磷酸化位点通常是CDKs和MAPKs的靶标,并往往能显著影响蛋白质的构象(4,5)。
This paper presents a fast exhaustive search algorithm in order to search the protein conformation space based on the lattice model by constructing a directional binary tree.
本文在构造具有方向导向性的完全二叉树的基础上,提出了一种适合研究蛋白质构象的格子模型快速穷举搜索算法。
This three-dimensional conformation is held together by the interactions of the amino acids at different parts of the polypeptide chain with each other, and determines the activity of the protein.
这种三维构造通过肽链上不同部位上的氨基酸连在一起,决定了蛋白活性。
This does not disturb the conformation of the protein molecules; but those in state "zero" absorb light at this wavelength.
这不会干扰蛋白质分子的构造,但那些“0”状态的蛋白质分子将吸收这个波长的光。
Objective To determine the characteristic conformation of Staphylococal protein A-gold.
目的确定葡萄球菌蛋白a胶体金分子特征性构象。
Recently, it has been proved that an mRNA molecule instructs the corresponding protein synthesizing not only in the primary structure but also in the conformation.
最近研究表明,信使RNA在蛋白质合成中,不但表现出一维序列上的对应,且在两者的空间构象上也表现出某些对应关系。
Modification of a protein usually refers to physical, chemical, or enzymatic treatments changing its conformation and structure and consequently its physicochemical and functional properties.
蛋白质的改性指的是用物理、化学或酶法改变蛋白质的构象和结构,从而改变其理化性质。
Therefore the conformation of protein can change and even the protein can be inactivated in the process of adsorption.
因此,蛋白质在吸附过程中,构象会发生变化,甚至导致失活。
In their structural studies, those scientists had found only the active conformation of EGFR in their protein crystals.
在他们的结构研究中,这些科学家已经发现,在他们制备的蛋白质晶体中,只存在活性构象的EGFR。
Antifreeze proteins are a kind of protein inhibiting the growth of ice crystals and modifying the conformation of ice crystals, conferring freeze resistance to biology without temperature modulation.
抗冻蛋白是一类抑制冰晶生长和修饰冰晶形态的蛋白质,赋予无体温调节能力的生物在低温的环境里得以生存。
CONCLUSION Penetration enhancers can change the fluidity of membrane lipid and the conformation of membrane protein in certain degrees, and increase the sublingual absorption of insulin.
结论渗透促进剂可以不同程度地影响膜脂流动性和膜蛋白构象,提高胰岛素经舌下给药后的降糖效果。
CONCLUSION the stability of the protein during spray drying was affected by crystallization, surface adsorption and conformation transformation.
结论蛋白质在喷雾干燥过程中的稳定性受载体结晶、表面富集和构象变化等多种机制影响。
BACKGROUND: the properties, integration mechanism and conformation change of protein are closely related with the biological effects of nanocomposites.
摘要:背景:纳米生物复合材料的性质、形成机制和蛋白质构象变化与其生物学效应密切相关。
Protein secondary structure prediction becomes the most important step of predicting the space conformation from protein molecule.
蛋白质二级结构预测是蛋白质结构预测的重要组成部分,是蛋白质结构预测最关键的步骤。
Protein secondary structure prediction becomes the most important step of predicting the space conformation from protein molecule.
蛋白质二级结构预测是蛋白质结构预测的重要组成部分,是蛋白质结构预测最关键的步骤。
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