Ubiquitin is a conserved polypeptide unit that plays an important role in the ubiquitin-proteasome pathway.
泛素是一种保守的多肽单元，在泛素蛋白酶体途径中起重要作用。
The ubiquitin-proteasome pathway is now considered as one of the most common regulatory processes in all eukaryotes.
泛素蛋白酶体途径是真核生物最普遍的调控过程之一。
The special characteristics of CHIP make it become the bridge of molecular chaperone system and ubiquitin-proteasome pathway.
CHIP的特殊结构特征使其成为沟通分子伴侣与泛素-蛋白酶体通路之间的桥梁，是蛋白质量控制系统的重要中介分子。
Protein degradation mediated by ubiquitin-proteasome pathway is an important mechanism which modulates cellular proteins′ activity and function.
泛素- 蛋白酶体途径介导的蛋白降解是机体调节细胞内蛋白水平与功能的一个重要机制。
Objective: To investigate the expression of ubiquitin-proteasome pathway in skeletal muscle of cachectic mice and the effect of indomethacin (ind) on it.
目的：研究泛素蛋白质酶途径在癌性恶病质小鼠骨骼肌中的表达以及吲哚美辛(IND)对其的调控作用。
Objective to investigate the role of ubiquitin-proteasome pathway (UPP) in the regulation of retinal cell apoptosis after experimental retinal detachment (RD).
目的探讨泛素-蛋白酶体通路(UPP)在实验性视网膜脱离(RD)中对视网膜细胞凋亡的调控作用。
Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development.
泛素- 蛋白酶体通路介导细胞蛋白质的降解，在细胞周期、基因转录及表达、 抗原提呈和炎症演进等方面发挥调控作用。
P42 is one subunit of 19s regulatory complex of 26s proteasome in ubiquitin-proteasome pathway, and it is also one subunit of modulator, which is 19s regulatory complex dependent.
p42是泛素蛋白水解酶通路中26s蛋白水解酶复合体19s帽状调节复合物的一个亚基，也是组成19s调节复合物依赖的蛋白水解酶调节子的一个组成成分。
Ubiquitin-proteasome pathway is an important mechanism regulating many processes of cellular biology, and also a potential target for abnormal regulation associated with malignancy.
泛素蛋白酶体途径是调节多种细胞生物学过程的重要机制，也是恶性肿瘤相关调节异常的潜在靶点；
The proteasome is an abundant multi-enzyme complex that provides the main pathway for degradation of intracellular proteins in eukaryotic cells.
蛋白酶体是真核细胞中含量丰富的多酶复合物，它主要协助降解细胞内的蛋白。
EIN3 is regulated by a proteasome-mediated protein degradation pathway.
EIN3受到蛋白酶体介导的蛋白降解途径的调节。
Inhibition of proteasome has been emerging as a promising approach in pathway-directed cancer therapy.
蛋白酶体的抑制在肿瘤的信号通路定向治疗方面已经成为一个极其有希望的途径。
The ubiquitin-proteasome proteolytic pathway, a major pathway for protein degradation in cells, plays a critical role in the protein metabolism.
泛素介导的蛋白质降解途径是降解细胞内蛋白质的主要途径，在维持细胞正常的蛋白质代谢中起着至关重要的作用。
The proteasome inhibitor MG-132 can reduce the lung injury induced by hyperoxia and inhibit P38MAPK signaling pathway.
蛋白酶体抑制剂MG- 132可以减轻高氧引起的肺损伤，可能对p 38 MAPK信号通路有抑制作用。
The proteasome inhibitor MG-132 can reduce the lung injury induced by hyperoxia and inhibit P38MAPK signaling pathway.
蛋白酶体抑制剂MG- 132可以减轻高氧引起的肺损伤，可能对p 38 MAPK信号通路有抑制作用。
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