But they do take a stab at the answer: 'Sleep disturbance influences the regulation of proinflammatory cytokines, histamines, and other symptom mediators that are released in response to infection.'
不过他们猜测原因可能是：睡眠不良会影响人体对促炎细胞因子、组胺和其他为应对病毒感染而释放的症状调节因子的调节。
Interleukin-6 is a pleiotropic cytokine with both proinflammatory and anti-inflammatory effects. It plays an important role in the pathophysiological processes of the acute cerebral infarction.
白细胞介素6是一种多效细胞因子，既有促炎作用又有抗炎作用，在脑梗死急性期的病理生理过程中起重要作用。
Kinins are proinflammatory peptides that are released during tissue injury.
激肽是在组织损伤时释放的一种促炎症反应的肽类物质。
Adipose tissue has been shown capable of expressing proinflammatory cytokines.
脂肪组织能表达促炎细胞因子。
Although thought to be associated with proinflammatory states, little work has been done in this area.
虽然被认为是与促炎症状态有关，但是在这一领域很少有人涉足。
This resistance may be related to proteins that down-regulate the expression of proinflammatory genes.
这种抵抗可能与下调炎症基因表达的蛋白质有关。
Recently, the traditional DNA-binding protein HMGB1 was discovered as a potent proinflammatory cytokine.
近年来发现高迁移率族蛋白B1（HMGB1）这一传统DNA结合蛋白是强大的致炎细胞因子。
Newer biological agents that work by inactivation of proinflammatory cytokines are available for treatment of RA.
能使促炎细胞因子失活的新型生物制剂也已应用于类风湿关节炎的治疗。
Inflammatory cells, proinflammatory cytokines and COX-2 play an important role in the process of lymphangiogenesis.
炎症细胞、促炎细胞因子和COX - 2等在肿瘤淋巴管生成过程中发挥了重要作用。
As an anti-inflammatory and proinflammatory adipocytokine, adiponectin plays a dual role in inflammatory processes.
而脂联素具有抗炎、促炎的双重作用。
Methods: Using LPS-induced microglia activation model and proinflammatory cytokines NO and MCP-1 were measured by ELISA.
方法：采用体外lps诱导小胶质细胞活化模型，用ELISA法测定细胞外液中NO和MCP - 1的含量。
Glucocorticoids and various proinflammatory cytokines are important regulators of muscle proteolysis in stressed patients.
在应激病人中，糖皮质激素和各种前炎症因子是肌肉蛋白质水解的重要调节因素。
Septic shock may be more proinflammatory than other forms because of the actions of bacterial toxins, especially endotoxin.
由于细菌毒素的作用，尤其是内毒素，败血症性休克的促炎症性反应强于其他休克。
Background: Interleukin (IL) -18 is a proinflammatory cytokine and plays important regulating roles in various immune reactions.
背景：白细胞介素(IL)鄄18是一种促炎性细胞因子，对多种免疫反应具有重要调节作用。
Objective: to define the relation between acute myocardial injury and release of proinflammatory cytokines in critically ill patients.
目的：探讨前炎细胞因子释放在危重病患者继发性心肌损伤中的作用。
These compounds activate dendritic cells to produce proinflammatory cytokines, which in turn trigger cytotoxic mechanisms leading to cancer death.
这些化合物能够启动树状突细胞产生致炎因子从而依次来引发可导致癌细胞死亡的细胞毒作用。
The method is useful for reducing inflammation caused by elevated levels of proinflammatory substances, including inflammation associated with an oral condition.
该方法可用于减少由升高水平的促炎物质引起的炎症，所述炎症包括与口腔疾病相关的炎症。
Study Design. In vitro studies of the effects of proinflammatory cytokines on the production of nerve growth factor (NGF) by human intervertebral disc (IVD) cells.
研究设计：对于致炎细胞因子刺激椎间盘细胞神经生长因子(NGF)作用的体外研究。
Conclusions: Tripterine has noticeable protective effects on TNBS-induced colitis in rats, suppression of proinflammatory cytokines may be one of its main mechanisms.
结论：雷公藤红素对TNBS诱导的大鼠结肠炎具有显著保护作用，抑制促炎细胞因子的产生可能是其主要作用机制之一。
The mechanism of anti-inflammatory is synthetical, including inhibitory effect of proinflammatory factor, immunomodulation, anti-oxidation and antimicrobial activity.
其抗炎机理与抑制炎症因子作用、免疫调节作用、抗氧化作用、抑菌作用等综合作用有关。
Objective To investigate effects of two proinflammatory cytokines on the production of plasminogen activator inhibitor 1(PAI 1) by human pleural mesothelial cells(HPMC).
目的研究前炎症细胞因子对人胸膜间皮细胞（HPMC）释放纤溶酶原激活物抑制剂（PAI1）的诱导效应。
In Crohn's disease, the proinflammatory state resulting from NOD2 mutations have been associated with a loss of antibacterial function of enterocytes such as paneth cells.
在克罗恩病中，由于NOD2基因突变导致的促炎症反应状态，已证实与肠细胞抗菌作用的丧失有关。
DEFB gene products are small antimicrobial proinflammatory peptides, and copy number variation (CNV) could reasonably influence susceptibility to infection and inflammation.
DEFB基因产物是小分子抗菌肽，且拷贝数变化(CNV)可显著影响易感性及炎症反应。
During proinflammatory reactions such as endotoxemia, ischemia - reperfusion and immune reactions, excessive amounts of cytokines and prostanoids are released resulting in liver injury.
在促炎症反应如内毒素、缺血再灌注损伤和免疫反应中，过量释放的细胞因子和前列腺素样物质可引起肝损伤。
ConclusionTongxinluo capsule has obvious inhibition effect on AA, and the action mechanism may be related with the antioxidation and inhibition of the production of proinflammatory cytokines.
结论通心络对大鼠佐剂性关节炎具有显著抑制作用，其作用机制可能与抑制前炎症细胞因子生成、抗氧化等有关。
PAF has been implicated as a mediator of physiological processes such as signaling and activation of proinflammatory cells, alteration of vascular permeability, and stimulation of glycogen metabolism.
PAF在许多生物学过程中，如前炎症细胞的信号传导和活化、改变血管通透性、刺激糖原代谢以及其它方面起着重要的作用。
Proinflammatory cytokines such as interleukin-1 and interleukin-6 have stimulatory effects on the synthesis of acute phase proteins (6, 7).
炎性细胞因子，如白细胞介素1和白细胞介素-6对合成急性期蛋白质(6,7)有促进作用。
Proinflammatory cytokines such as interleukin-1 and interleukin-6 have stimulatory effects on the synthesis of acute phase proteins (6, 7).
炎性细胞因子，如白细胞介素1和白细胞介素-6对合成急性期蛋白质(6,7)有促进作用。
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