The principal question in drug design is how to study the ligand-binding sites and others because of the poor structure information.
如何在生物胺受体结构数据严重匮乏的基础上研究受体的配基结合位点及其它功能位点，已成为药物设计中的关键问题。
The principal drivers have been largely external rather than internal, calling into question whether those principals are core to the companies DNA.
主要的推动因素在很大程度上一直是外部而不是内部的，对这些推动因素是否是企业DNA的核心一直是有疑问的。
But others question the likelihood of success without reducing the principal.
但是有人质疑，在不降低本金的情况下，这样做成功的可能性有多大。
Presumably only some fraction of the woman's online contacts even saw the post in question — possibly a small fraction, says Duncan Watts, a principal research scientist in Yahoo!
或许只有部分在线联系人看到了那女人贴出的内容有问题——可能只是很少的人。
U.S. Treasuries are still triple-A in that there is no question that we will repay the interest and the principal.
美国国债依然是3A评级，毕竟，我们肯定能够偿还利息和本金，这一点是毋庸置疑的。
“That’s a real concern and question, ” said James Russell, an atmospheric scientist at Hampton University and the principal investigator of an ongoing NASA satellite mission to study the clouds.
“那是真正要关切和质疑的，”詹姆斯·拉塞尔说。 他是汉普顿大学的大气科学家，也是美国航天局正在进行中的卫星飞行任务中研究云团的首席研究员。
By the Construction phase, with the technical risks effectively mitigated, the principal focus turns to the question "Can we get all the work done by the end of the phase?"
在构建阶段，技术风险大大降低，此时的主焦点问题是“我们在此阶段结束之前能够完成所有的必要任务吗？”
To answer this question, we need to plot trajectories of principal stresses.
研究了一种简便快速的主应力迹线自动化绘制方法。
Union and reorganization of principal industry directly results in the question of non-principal industrys capital operation.
主业联合重组的对偶问题是非主业产业的资本运营问题。
The Principal took on the first question and described her plan for this semester. Monthly newsletter, joy of reading, and library tour will continue from last year.
第一个问题是有关校务，校长概述了这个学期的几项活动，有继续去年每月发刊的简讯，读书乐，以及图书馆介绍。
National Public Radio asked exactly this question in a survey a year or so ago and they got the following principal responses back.
国家公共广播电台问过，完全相同的问题，在一次一年前的民意调查中，他们得到了如下的回复。
The principal wondered, why does she ask such a question!
校长诧异，她怎么会问这样一个问题。
Well, it would serve to cure him of an absurd practice of never asking a question at an inn, which he had adopted, when quite a young man, on the principal of its being very ungenteel to be curious.
唔，那还可以帮助我纠正在旅馆决不向人发问的荒诞做法，我还是在很年轻的时候，就开始遵循好奇者不礼貌的原则。
This paper is the sub-question of the project "The Green Building System and theModel of Principal Unit of Human Settlement in Loess Plateau" funded by NNSF of China.
本论文是国家自然科学基金重点资助项目《黄土高原绿色建筑体系与基本聚居单位住区模式》的子课题之一。
This paper is the sub-question of the project "The Green Building System and theModel of Principal Unit of Human Settlement in Loess Plateau" funded by NNSF of China.
本论文是国家自然科学基金重点资助项目《黄土高原绿色建筑体系与基本聚居单位住区模式》的子课题之一。
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