International Diabetes: metformin is often viewed as an insulin sensitizer. What is the difference between metformin and pioglitazone with regard to improving insulin resistance?
《国际糖尿病》：二甲双胍通常被看作是胰岛素增敏剂。在改善胰岛素抵抗方面，二甲双胍和吡格列酮的区别有哪些？
Pioglitazone was tested in combination with a sulfonylurea, insulin, or metformin in 8 trials (8501 patients).
吡格列酮联用磺脲类、胰岛素或者二甲双胍用于8项试验(8501个病人)。
The metformin and pioglitazone are insulin sensitizers so they never lower you blood glucose below normal and the GLP-1 analogues or DPP-IV inhibitors also never lower your blood glucose below normal.
二甲双胍和吡格列酮都是胰岛素增敏剂，因此这两类药物不会导致低血糖，而GLP-1类似物或DPP-IV抑制剂导致低血糖的概率也很低。
The metformin and pioglitazone are insulin sensitizers so they never lower you blood glucose below normal and the GLP-1 analogues or DPP-IV inhibitors also never lower your blood glucose below normal.
二甲双胍和吡格列酮都是胰岛素增敏剂，因此这两类药物不会导致低血糖，而GLP-1类似物或DPP-IV抑制剂导致低血糖的概率也很低。
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