Conclusion Human anti-keratin scFv is obtained from a large phage antibody library, which will benefit to the application of anti-keratin antibody to clinical research.
结论利用噬菌体抗体库技术获得了人源性抗角蛋白单链抗体，为临床应用研究提供了具有更广阔应用前景的人源小分子抗体。
AIM: To obtain in situ pairing of the variable region genes of the heavy and light chains of vitiligo patients' lymphocytes, then construct and screen a human ScFv phage antibody library.
目的克隆白癜风患者淋巴细胞中原始配对的自身抗体基因，构建噬菌体抗体库并筛选针对黑素细胞膜抗原的特异性抗体。
Results The ScFv phage repertoire with capacity of 107 was obtained.
结果获得库容量约为107噬菌体抗体库。
The construction of phage library of scFV antibody.
人源性天然抗体库的构建。
The construction of phage library of scFV antibody.
人源性天然抗体库的构建。
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