Lo and behold, doses of both fats and cytokines caused PGC-1 alpha to be methylated.
请看，大量的脂肪和细胞因子一起把PGC - 1甲基化了。
So, this time, before bathing the healthy cells in fats or cytokines, the team added a chemical that blocks the activity of DNMT3B, an enzyme which they found methylates PGC-1 alpha.
所以，这次在把正常细胞放入脂肪和细胞因子之前，研究人员加入了一种能阻碍DNMT3B活动的化学物质，即一种会使PG C - 1甲基化的酶。
It is well known that poor diet and lack of exercise make insulin resistance more likely, so one hypothesis is that these things change the epigenetic marks on genes such as PGC-1 alpha.
众所周知，饮食不健康或缺乏锻炼更易导致胰岛素阻抗，所以有假设说，这些情况会改变譬如pgc - 1这样的基因上的外遗传标签。
Lo and behold, doses of both fats and cytokines caused PGC - 1 alpha to be methylated.
请看，大量的脂肪和细胞因子一起把PGC - 1甲基化了。
Lo and behold, doses of both fats and cytokines caused PGC - 1 alpha to be methylated.
请看，大量的脂肪和细胞因子一起把PGC - 1甲基化了。
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