Nowadays, protein coevolution analysis is mainly based on coefficient correlation methods, perturbation methods and parameter test.

当前分析共进化残基的方法主要有基于相关系数的方法、基于微扰理论的方法、参数检验法等。

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Under the circumstances of no perturbation and with perturbation in coefficient matrix, both LS and TLS estimators were proposed.

根据系统数据矩阵不存在扰动和存在扰动两种情况，分别给出波达方向的最小二乘估计和总体最小二乘估计。

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Under the circumstances of no perturbation and with perturbation in coefficient matrix, both LS and TLS estimators were proposed.

根据系统数据矩阵不存在扰动和存在扰动两种情况，分别给出波达方向的最小二乘估计和总体最小二乘估计。

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