• Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer?

    PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用? ?

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  • Nimodipine can inhibit the expression of VEGF and PDGF to a certain extent.

    尼莫地平在某种程度上能抑制VEGF及PDGF的表达。

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  • The most recent biologic modifier is platelet derived growth factor (PDGF).

    当今最先进的生物改性剂是血小板源性生长因子(PDGF)。

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  • Three dimension cell culture found PDGF could induce endothelial cell angiogenesis in vitro.

    PDGF有利于三维培养内皮细胞在有展性的胶原基质面形成血管样结构。

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  • In one month diabetic rat retina, there was also obvious increase of PDGF-B expression on Protein level;

    一个月时,糖尿病大鼠视网膜内PDGF-B在蛋白水平上的表达也是增加的;

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  • Conclusion Nitric oxide inhibited PDGF expression by pulmonary arteries of rats with hypoxic pulmonary vascular remodeling.

    结论一氧化氮对缺氧性肺血管结构重建大鼠肺动脉中PDGF表达有抑制作用。

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  • AIM: to investigate the effects of platelet-derived growth factor BB (PDGF-BB) on vasoconstriction of the vascular vessels.

    目的:观察血小板衍生生长因子-BB (PDGF - BB)对大鼠主动脉血管环的收缩作用。

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  • The cell culture liquid containing PDGF-BB was active and could be neutralized by the polyclonal antibody of human PDGF-BB.

    MTT方法较为稳定,PDGF—BB细胞培养液具有一定活性,并能被抗人PDGF-BB 多克隆抗体中和。

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  • After placement of the graft material-enriched PDGF, a coat of PRP plasma is placed over the graft area and the flaps closed.

    在富含PDGF的移植材料放置好后,将PR P血浆膜覆盖在移植区并关闭瓣膜。

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  • The contents of PDGF-BB were obviously higher than those of control group (all P<0.05), and they gradually reduced with time.

    而PDGF-BB含量也明显高于对照组(P均<0.05),但随术后时间延长逐渐恢复降低。

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  • Conclusion: SM injection might attenuate the delayed injury induced by intracerebral hemorrhage via regulating the expression of PDGF.

    结论:参麦注射液可能通过调节pdgf表达对脑出血后迟发性神经细胞损伤修复有保护作用。

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  • Conclusion Partial dorsal root rhizotomy exerts different influence on the expression of CNTF and PDGF for different neurons in spared DRG.

    结论部分背根切断对备用背根节内不同神经元表达CNTF、PDGF有不同的影响。

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  • Objective to study the expression and change of regularity of endogenous Platelet derived growth factor (PDGF) in the process of wound healing in rat skin.

    目的探讨创伤模型大鼠皮肤创面愈合过程中,血小板源生长因子(PDGF)表达的动态变化。

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  • Conclusion: PDGF expression is obviously increased in OIR patients nimodipine can prevent OIR and it can inhibit the expression of PDGF to a certain extent.

    结论:PDGF在OIR组织中表达明显增加,而钙通道拮抗剂尼莫地平可抑制OIR的发生,并在某种程度上抑制PDGF的表达。

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  • Objective: to explore the role of platelet derived growth factor-B (PDGF-B) on spinal cord functional recovery after acute spinal cord injury (SCI) in rats.

    目的:探讨血小板衍化生长因子- B (PDGF - B)在脊髓损伤(SCI)后对脊髓功能恢复的作用。

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  • This factor was not expressed in normal arteries, but expression of PDGF has increased after angioplasty or atherosclerosis induced endothelial cell injury.

    此因子在正常动脉中不表达,但在血管成型术后或者动脉粥样硬化引起的内皮细胞损伤时表达量都有所增加。

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  • Objective to investigate the biological effects of platelet-derived growth factor (PDGF) -bb on the osteoclasts in the osteoblast-osteoclast co-culture system.

    目的探讨血小板衍生生长因子(PDGF) -BB在成骨细胞-破骨细胞培养体系中对破骨细胞骨吸收功能的影响。

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  • Objective to observe the role of platelet-derived growth factor-B (PDGF-B) in the regeneration of peripheral nerve by studying its expression on injured rat sciatic nerves.

    目的:观察血小板源性生长因子b (PDGF - B)在损伤大鼠坐骨神经中的表达,旨在阐明其在末梢神经再生中的作用。

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  • Furhermore, PDGF-A did not seem to act directly on the tumour cells, but was instead released into the space outside of the cell suggesting an effect on neighbouring cells.

    而且PDGF - A似乎没有直接作用于肿瘤细胞,而是释放至细胞周围,对附近细胞产生影响。

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  • And in fact, PDGF-A (and so progesterone) was found to increase the growth and viability of smooth muscle cells confirming a role to both these molecules supporting angiogenesis.

    实际上,发现PDFA - A(因此孕酮也)增加平滑肌细胞的生长和活力,证明这两种分子都有支持血管发生的作用。

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  • Conclusion PDGF may participate in glomerular cells proliferation and inflammatory cells infiltration in LN, and may be on factor in the different pathological type formation of LN.

    结论PD GF在LN的细胞增生和炎症浸润过程中发挥一定作用,可能是造成不同ln病理类型的中间因素之一。

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  • PURPOSE The study was carried to observe the effect of platelet-drived growth factor(PDGF) on the cellular proliferation and synthesis of procollagen of rat pulmonary fibroblasts (PFbs).

    观察血小板源性生长因子(PDGF)对肺纤维母细胞增殖、胶原合成的影响。

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  • ConclusionRuangan Huajian granule may alleviate the degree of liver inflammation and fibrosis through reducing hepatic expression of PDGF-B in C57 mice with experimental hepatic fibrosis.

    结论软肝化坚颗粒可能通过降低C57小鼠肝组织pdgf - B的表达,进而减轻肝纤维化程度和肝组织损伤。

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  • Objective to investigate effects of PDGF on phenotypic change of glomerular mesangial cells (MC), and study intracellular mechanisms through mitogen-activated - protein kinase (MAPK) pathways.

    目的研究血小板源生长因子(PDGF)对肾小球系膜细胞(MC)表型转化的影响,并探讨丝裂素活化蛋白激酶(MAPK)信号转导途径在其作用中的调控机制。

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  • The expression of PDGF a was mainly found in the renal distal tubule and epithelial cells of distal straight tubule and glomerulus capillary, but IGF 1 in transplanting artery equal expressed.

    而在肾组织中PD GFA与IGF 1的表达均主要集中在远曲小管、远直小管上皮细胞及肾小球毛细血管上皮细胞。

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  • Objective: to investigate the effect of platelet derived growth factor (PDGF) and heparin on regulating the transformation of phenotype and collagen synthesis in aorta smooth muscle cell (SMC).

    目的:研究、探讨血小板源生长因子和肝素对培养的人主动脉平滑肌细胞表型转变调节作用,及其对平滑肌细胞胶原蛋白合成的影响。

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  • Platelet-derived growth factor C (PDGF-C) is a recently identified member of the PDGF family. PDGF-C contributes to normal development of the heart, central nervous system, kidney and palatogenesis.

    血小板衍生生长因子C(PDGF-C)近来被证实是PDGF家族中的一员,它参与了心脏、中枢神经系统、肾脏和腭板的正常发育。

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  • Objective to investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB (PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells.

    目的研究血小板衍生生长因子bb (PDGF - BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。

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  • Objective to investigate the intracellular calcium concentration alteration induced by platelet-derived growth factor BB (PDGF-BB) and the mechanism of ion flux in cultured glomerular mesangial cells.

    目的研究血小板衍生生长因子bb (PDGF - BB)引起的肾小球系膜细胞内游离钙浓度变化及其离子流动机制。

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