• Conclusion EDT can protect PC12 cells from anoxia and ischemic injury.

    结论EDT对PC 12细胞缺血缺氧损伤具有保护作用。

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  • Rotenone was used on NGF-differentiated PC12 cells to induce apoptosis.

    以ngf诱导后的PC 12细胞作为细胞模型,采用鱼藤酮诱导细胞凋亡。

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  • The culture supernatant could stimulate the neurite outgrowth of PC12 cells.

    阳性克隆培养上清能促进PC 12细胞突起生长。

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  • Objective: To explore the effect of p35 on MnCl2-induced apoptosis in PC12 cells.

    目的:探讨p35基因对氯化锰(MnCl2)诱导的PC12细胞凋亡的作用。

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  • Objective To observe the effects of electromagnetic acute irradiation on PC12 cells.

    目的探讨电磁辐射急性辐照对PC 12细胞的影响。

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  • Results; Reserpine, an inhibitor of VMAT, itself had no poisonous effect on PC12 cells.

    结果:单独加入VMAT抑制剂利血平对PC12细胞无毒性作用;

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  • Conclusion Bupivacaine is cytotoxic to PC12 cells in a concentration - dependent manner.

    结论布比卡因对PC 12细胞具有浓度依赖性的细胞毒性作用。

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  • OBJECTIVE To investigate the neurotrophic and neuroprotective effects of panaxynol on PC12 cells.

    目的探讨人参炔醇对神经细胞的营养及保护作用。

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  • The retrieved encapsulated PC12 cells were recultured and their activities were tested by MTT and Trypan blue test.

    对移植的微囊化PC12细胞回收后再培养,以MTT和台盼兰检测细胞活性。

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  • Conclusion Under hypoxic conditions, propofol can cause apoptosis in PC12 cells by inducing oxidative stress injury.

    结论低氧环境下丙泊酚可通过氧化应激损伤导致PC 12细胞凋亡增加。

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  • Aim: to observe the proliferating process in early cultured PC12 cells so as to investigate the tumor evolving process.

    目的:观察早期培养的PC 12细胞以了解肿瘤细胞演化过程。

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  • Objective to investigate the effect of propofol on cytotoxicity of bupivacaine on PC12 cells and its possible mechanism.

    目的探讨异丙酚对布比卡因诱导的PC 12细胞毒性的作用及其可能机制。

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  • Objective To investigate the effects of prion protein 106-126 peptide on inducing apoptosis in differentiated PC12 cells.

    目的:研究朊蛋白106-126肽段在细胞水平上的毒性作用。

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  • Conclusion PS-1 mutant L286V plays a role in inhibiting the growth and accelerating the apoptosis of RA-induced PC12 cells.

    结论PS - 1突变型L 286 V对RA诱导的PC 12细胞生长具有抑制作用和促进细胞凋亡的作用。

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  • The well growth and the good biological activities of the retrieved PC12 cells were proved using the MTT and Trypan blue test.

    回收微囊化PC12细胞再培养生长良好,MTT法和台盼兰法检测显示细胞具有生物活性。

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  • Adding glutathione (GSH), dithiothreitol (DTT) and pulse number 1 could significantly increase the survival rate of PC12 cells.

    加入还原型谷胱甘肽(GSH)、二硫苏糖醇(DTT)和脉冲1号使PC 12细胞的生存率明显提高。

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  • Objective To study the formation and development of inclusions in dopaminergic PC12 cells treated with proteasome inhibitor PSI.

    目的研究蛋白酶体抑制剂PSI诱导PC12细胞胞浆内嗜酸性包涵体的形成及演变过程。

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  • Conclusion Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely.

    结论:朊蛋白106- 126肽段能够诱导分化后的PC 12细胞凋亡,具有明确的毒性作用。

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  • Conclusion FMD has good scavenging effect to ROS, and can protect PC12 cells from oxidative stress injury induced by hydrogen peroxide.

    结论FMD对氧自由基、羟自由基等ROS具有很好的清除作用,并对过氧化氢诱导的PC 12损伤具有良好的保护作用。

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  • Methods PC12 cells and BV2 cells, instead of neurons and microglia separately, were co-cultivated in transfer screen by cell passage method.

    方法采用细胞株传代法培养PC12细胞及BV2细胞,分别替代神经元细胞和小胶质细胞;

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  • Conclusions Simulated weightlessness may induce the (over) production of NO, and resulted in increased protein oxidative damage in PC12 cells.

    结论模拟失重可诱导PC 12细胞NO的合成,增加蛋白质氧化损伤程度。

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  • Objective To investigate the protective effect of gross saponins of tribulus terrestris(GSTT) on H2O2-induced oxidative-stress damage in PC12 cells.

    目的探讨蒺藜皂苷(GSTT)对H2O2诱导的PC12细胞氧化应激损伤的保护作用。

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  • METHODS Natural products were collected to screen in the stable cell line of GLP-1 receptor, and the active component was identified in the PC12 cells.

    方法建立稳定的GLP-1受体激动剂高通量筛选模型,从天然药物中筛选活性成分;在PC12细胞中验证GLP-1受体激动剂的功能及作用机制。

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  • Water extracts of dry and fresh P. ginseng had apparent protective effect on corticosterone-induced and hydrogen peroxide-induced damage in PC12 cells;

    干、鲜人参水提液对于皮质酮、过氧化氢诱导损伤的PC12细胞均有明显的保护作用;

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  • ResultsThe supernatant of lymphocytes modified by BDNF gene decreased the growth inhibitory rate and apoptosis rate of PC12 cells induced by H2O2 and DA.

    BDNF基因修饰的大鼠淋巴细胞的培养上清可降低H2O2和DA对PC 12细胞生长的抑制率并能抑制H2O2和DA诱导PC 12细胞凋亡。

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  • Objective: to investigate the protective effect of the hypoxia-inducible factor-1 relevant peptide (BW8) on chemical hypoxia-induced injury in PC12 cells.

    目的:研究氯化钴模拟化学缺氧条件下,缺氧诱导因子1相关肽(BW8)对PC 12细胞损伤的影响。

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  • Objective To explore the death types of PC12 cells injured by a high concentration of zinc, and effects of inosine on the types of zinc-induced cell death.

    目的探讨高浓度锌损伤后PC 12细胞的死亡类型和肌苷对该死亡类型的影响。

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  • Objective: to observe the effect of nerve growth factor (NGF) on cell cycle in PC12 cells, and to establish a cell cycle model of neuron-like cell in vitro.

    目的:观察神经生长因子(NGF)诱导PC 12细胞周期的变化,以建立体外神经元样细胞周期的研究模型。

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  • Objective: to investigate the possible protective effects and related mechanisms of olanzapine on PC12 cells, apoptosis induced by serum-free culture was observed.

    目的:探讨奥氮平对无血清诱导PC 12细胞凋亡的保护作用及其机制。

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  • Objective To evaluate the expression level of glucose regulating protein 78(GRP78) in the model of Parkinson's disease(PD)induced by 6-Hydroxydopamine(6-OHDA) in PC12 cells.

    目的探讨神经毒素6-羟基多巴胺(6-OHDA)诱导PC12细胞的帕金森(PD)模型中GRP78的表达。

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