Conclusion EDT can protect PC12 cells from anoxia and ischemic injury.
结论EDT对PC 12细胞缺血缺氧损伤具有保护作用。
Rotenone was used on NGF-differentiated PC12 cells to induce apoptosis.
以ngf诱导后的PC 12细胞作为细胞模型,采用鱼藤酮诱导细胞凋亡。
The culture supernatant could stimulate the neurite outgrowth of PC12 cells.
阳性克隆培养上清能促进PC 12细胞突起生长。
Objective: To explore the effect of p35 on MnCl2-induced apoptosis in PC12 cells.
目的:探讨p35基因对氯化锰(MnCl2)诱导的PC12细胞凋亡的作用。
Objective To observe the effects of electromagnetic acute irradiation on PC12 cells.
目的探讨电磁辐射急性辐照对PC 12细胞的影响。
Results; Reserpine, an inhibitor of VMAT, itself had no poisonous effect on PC12 cells.
结果:单独加入VMAT抑制剂利血平对PC12细胞无毒性作用;
Conclusion Bupivacaine is cytotoxic to PC12 cells in a concentration - dependent manner.
结论布比卡因对PC 12细胞具有浓度依赖性的细胞毒性作用。
OBJECTIVE To investigate the neurotrophic and neuroprotective effects of panaxynol on PC12 cells.
目的探讨人参炔醇对神经细胞的营养及保护作用。
The retrieved encapsulated PC12 cells were recultured and their activities were tested by MTT and Trypan blue test.
对移植的微囊化PC12细胞回收后再培养,以MTT和台盼兰检测细胞活性。
Conclusion Under hypoxic conditions, propofol can cause apoptosis in PC12 cells by inducing oxidative stress injury.
结论低氧环境下丙泊酚可通过氧化应激损伤导致PC 12细胞凋亡增加。
Aim: to observe the proliferating process in early cultured PC12 cells so as to investigate the tumor evolving process.
目的:观察早期培养的PC 12细胞以了解肿瘤细胞演化过程。
Objective to investigate the effect of propofol on cytotoxicity of bupivacaine on PC12 cells and its possible mechanism.
目的探讨异丙酚对布比卡因诱导的PC 12细胞毒性的作用及其可能机制。
Objective To investigate the effects of prion protein 106-126 peptide on inducing apoptosis in differentiated PC12 cells.
目的:研究朊蛋白106-126肽段在细胞水平上的毒性作用。
Conclusion PS-1 mutant L286V plays a role in inhibiting the growth and accelerating the apoptosis of RA-induced PC12 cells.
结论PS - 1突变型L 286 V对RA诱导的PC 12细胞生长具有抑制作用和促进细胞凋亡的作用。
The well growth and the good biological activities of the retrieved PC12 cells were proved using the MTT and Trypan blue test.
回收微囊化PC12细胞再培养生长良好,MTT法和台盼兰法检测显示细胞具有生物活性。
Adding glutathione (GSH), dithiothreitol (DTT) and pulse number 1 could significantly increase the survival rate of PC12 cells.
加入还原型谷胱甘肽(GSH)、二硫苏糖醇(DTT)和脉冲1号使PC 12细胞的生存率明显提高。
Objective To study the formation and development of inclusions in dopaminergic PC12 cells treated with proteasome inhibitor PSI.
目的研究蛋白酶体抑制剂PSI诱导PC12细胞胞浆内嗜酸性包涵体的形成及演变过程。
Conclusion Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely.
结论:朊蛋白106- 126肽段能够诱导分化后的PC 12细胞凋亡,具有明确的毒性作用。
Conclusion FMD has good scavenging effect to ROS, and can protect PC12 cells from oxidative stress injury induced by hydrogen peroxide.
结论FMD对氧自由基、羟自由基等ROS具有很好的清除作用,并对过氧化氢诱导的PC 12损伤具有良好的保护作用。
Methods PC12 cells and BV2 cells, instead of neurons and microglia separately, were co-cultivated in transfer screen by cell passage method.
方法采用细胞株传代法培养PC12细胞及BV2细胞,分别替代神经元细胞和小胶质细胞;
Conclusions Simulated weightlessness may induce the (over) production of NO, and resulted in increased protein oxidative damage in PC12 cells.
结论模拟失重可诱导PC 12细胞NO的合成,增加蛋白质氧化损伤程度。
Objective To investigate the protective effect of gross saponins of tribulus terrestris(GSTT) on H2O2-induced oxidative-stress damage in PC12 cells.
目的探讨蒺藜皂苷(GSTT)对H2O2诱导的PC12细胞氧化应激损伤的保护作用。
METHODS Natural products were collected to screen in the stable cell line of GLP-1 receptor, and the active component was identified in the PC12 cells.
方法建立稳定的GLP-1受体激动剂高通量筛选模型,从天然药物中筛选活性成分;在PC12细胞中验证GLP-1受体激动剂的功能及作用机制。
Water extracts of dry and fresh P. ginseng had apparent protective effect on corticosterone-induced and hydrogen peroxide-induced damage in PC12 cells;
干、鲜人参水提液对于皮质酮、过氧化氢诱导损伤的PC12细胞均有明显的保护作用;
ResultsThe supernatant of lymphocytes modified by BDNF gene decreased the growth inhibitory rate and apoptosis rate of PC12 cells induced by H2O2 and DA.
BDNF基因修饰的大鼠淋巴细胞的培养上清可降低H2O2和DA对PC 12细胞生长的抑制率并能抑制H2O2和DA诱导PC 12细胞凋亡。
Objective: to investigate the protective effect of the hypoxia-inducible factor-1 relevant peptide (BW8) on chemical hypoxia-induced injury in PC12 cells.
目的:研究氯化钴模拟化学缺氧条件下,缺氧诱导因子1相关肽(BW8)对PC 12细胞损伤的影响。
Objective To explore the death types of PC12 cells injured by a high concentration of zinc, and effects of inosine on the types of zinc-induced cell death.
目的探讨高浓度锌损伤后PC 12细胞的死亡类型和肌苷对该死亡类型的影响。
Objective: to observe the effect of nerve growth factor (NGF) on cell cycle in PC12 cells, and to establish a cell cycle model of neuron-like cell in vitro.
目的:观察神经生长因子(NGF)诱导PC 12细胞周期的变化,以建立体外神经元样细胞周期的研究模型。
Objective: to investigate the possible protective effects and related mechanisms of olanzapine on PC12 cells, apoptosis induced by serum-free culture was observed.
目的:探讨奥氮平对无血清诱导PC 12细胞凋亡的保护作用及其机制。
Objective To evaluate the expression level of glucose regulating protein 78(GRP78) in the model of Parkinson's disease(PD)induced by 6-Hydroxydopamine(6-OHDA) in PC12 cells.
目的探讨神经毒素6-羟基多巴胺(6-OHDA)诱导PC12细胞的帕金森(PD)模型中GRP78的表达。
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