• Method PC12 cell was exposed to H2O2 in vitro to establish oxidative injury model.

    方法体外细胞培养,H2O2处理PC 12细胞复制氧化损伤模型。

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  • The protective effects of rat serum concentrating HJD or its components on PC12 cell were assessed.

    观察HJD全方,单味药大鼠含药血清PC12细胞的保护作用

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  • The screening results showed that most of polysaccharide fractions induced the differentiation of PC12 cell.

    PC12细胞实验结果表明,多个多糖组分能刺激PC12细胞产生神经纤维样突起。

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  • Methods An ischemic model was developed in PC12 cell line with treatment of oxygen glucose deprivation (OGD).

    方法采用葡萄糖剥夺(ogd)方法PC 12细胞上建立缺血模型

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  • Objective Our study examined the protective effects of superoxide dismutase (SOD)on PC12 cell induced by enriched uranium.

    目的研究超氧化物歧化酶(SOD浓缩铀诱导PC12细胞凋亡保护作用

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  • Abstract: This study investigated the protective action of sweet potato extract to PC12 cell injury induced by glutamic acid.

    摘要观察甘薯提取物谷氨酸诱导PC 12细胞损伤保护作用

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  • Abstract: Objective to investigate the mechanism by which propofol exposure causes PC12 cell apoptosis under hypoxic conditions.

    摘要目的探讨低氧环境下泊酚对PC 12细胞株凋亡的影响及机制

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  • Methods PC12 cells and BV2 cells, instead of neurons and microglia separately, were co-cultivated in transfer screen by cell passage method.

    方法采用细胞株传代培养PC12细胞BV2细胞,分别替代神经元细胞小胶质细胞;

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  • METHODS Natural products were collected to screen in the stable cell line of GLP-1 receptor, and the active component was identified in the PC12 cells.

    方法建立稳定GLP-1受体激动剂高通量筛选模型,从天然药物筛选活性成分PC12细胞中验证GLP-1受体激动剂的功能作用机制。

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  • Objective To explore the death types of PC12 cells injured by a high concentration of zinc, and effects of inosine on the types of zinc-induced cell death.

    目的探讨高浓度损伤PC 12细胞死亡类型肌苷死亡类型的影响

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  • Objective: to observe the effect of nerve growth factor (NGF) on cell cycle in PC12 cells, and to establish a cell cycle model of neuron-like cell in vitro.

    目的观察神经生长因子(NGF)诱导PC 12细胞周期变化,建立体外神经元样细胞周期研究模型

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  • AIM: To study the effects of marrow stromal cells conditioned medium (CM) on proliferation and differentiation of PC12 cells, meanwhile whether CM can protect PC12 cell from the damage of rotenone.

    目的观察骨髓基质细胞条件液对PC 12细胞生长分化影响,分析其能否保护PC 12细胞免受鱼酮的毒性作用。

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  • Results SOD significantly reduced the rapid decrease of the cell viability and DNA chain fragmentation when treated with enriched uranium and markedly enhanced the free spermidine of PC12 cell. Concl…

    结果SOD可抑制浓缩铀诱发细胞活性迅速下降DNA断裂,同时提高细胞内游离精脒含量。

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  • The trial about the resist senile dementia was carried out with PC12 cell cultured by NGF, results showed H-1 and H-2 have not obvious effects on promoting NGF growth activity and reducing cell death.

    论文首次利用NGF培养PC12细胞做了H-1H-2两个神经鞘苷化合物的单体活性试验发现两个化合物均无明显促进NGF生长活性减少细胞凋亡及老年痴呆作用

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  • NECL2 distributed in cell body and protuberance of primary culture neuron. The rat adrenal gland tumor cell line PC12 can be induced into neuronal differentiation.

    肾上腺嗜铬细胞瘤细胞PC12具有神经元分化潜能,PC12细胞中转染并过量表达NECL2能够诱导细胞发生神经元样分化。

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  • NECL2 distributed in cell body and protuberance of primary culture neuron. The rat adrenal gland tumor cell line PC12 can be induced into neuronal differentiation.

    肾上腺嗜铬细胞瘤细胞PC12具有神经元分化潜能,PC12细胞中转染并过量表达NECL2能够诱导细胞发生神经元样分化。

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