What Dr Yamanaka discovered in his work on mice was a group of transcription factors that switched on the pattern of gene expression which says, “I am an embryonic stem cell.”
Yamanaka通过对老鼠进行实验发现有一组转录因子可以改变基因的表达方式，让这些基因说：“我就是胚胎干细胞”。
BACKGROUNDTissue specific pattern of gene expression is probably determined by regulatory modules encoded in the genome DNA and trans-regulatory apparatus.
研究背景：组织特异的基因表达是由基因组非编码区中的调控模块和对应的蛋白反式因子共同决定的。
BACKGROUNDTissue specific pattern of gene expression is probably determined by regulatory modules encoded in the genome DNA and trans-regulatory apparatus.
研究背景：组织特异的基因表达是由基因组非编码区中的调控模块和对应的蛋白反式因子共同决定的。
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