AIM: To investigate the effects of transfected JWA ribozyme gene on phenotype and migration of human pulmonary artery smooth muscle cells (PASMCs).
目的：探讨JWA核酶基因转染对肺动脉平滑肌细胞表型及迁移的影响。
The expression of NHE-1 in the membrane of PASMCs is elevated remarkably under hypoxia condition and the NHE-1 specific inhibitors can suppress the PASMCs proliferation.
肺动脉平滑肌细胞膜亦有NHE-1表达，在低氧条件下表达明显增高，其特异性抑制剂可明显抑制肺动脉平滑肌细胞增殖。
The expression of NHE-1 in the membrane of PASMCs is elevated remarkably under hypoxia condition and the NHE-1 specific inhibitors can suppress the PASMCs proliferation.
肺动脉平滑肌细胞膜亦有NHE-1表达，在低氧条件下表达明显增高，其特异性抑制剂可明显抑制肺动脉平滑肌细胞增殖。
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