• In normal cells, p21 ACTS like a brake to block cell cycle progression in the event of DNA damage, preventing the cells from dividing and potentially becoming cancerous.

    在正常的细胞中,如果DNA受损,p21就会像刹车一样阻断细胞周期进程以防止细胞分裂和癌变。

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  • The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression.

    肿瘤抑制蛋白p21Waf1/Cip1可以作为细胞周期的抑制因子。

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  • Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy-terminus of human p21.

    该单克隆抗体是由合成的人源的针对p 21蛋白羧基末端的肽段免疫动物生产的。

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  • Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human p21 protein.

    单克隆抗体由合成肽段免疫动物产生,该肽段与人p 21蛋白的羧基端一致。

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  • Serum P21 may be as screening index of lung cancer in high risk people.

    检测血清p 21蛋白水平可作为肺癌高危人群的筛检指标。

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  • Serum P21 and chronic respiratory disease were_compared between two groups.

    比较接触组与对照组的血清P21水平、慢性呼吸道疾病的发生情况。

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  • P21 may participate in the pathogenesis of renal tubule-interstitial fibrosis.

    P21可能参与肾小管间质纤维化的发病过程。

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  • Some affecting factors of serum P21 and the correlation of the exposed time and serum P21 were analysed.

    分析影响血清p 21蛋白水平的因素、及炼焦工龄与血清p 21蛋白表达水平的关系。

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  • Objective To investigate the expression of P21 in renal interstitial fibrosis rats and the effect of enalapril on it.

    目的:动态观察P 21在单侧输尿管梗阻肾间质纤维化大鼠模型中的表达,以及依那普利对其表达的调节。

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  • The risk factors of increasing serum P21 were the exposed time and pickle foods and the protective factor was fresh fruits.

    炼焦工龄、多食腌菜是导致血清p 21蛋白水平升高的危险因素,多食新鲜水果为保护因素。

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  • AIM: To evaluate the relationship between RUNX3, cyclin e, P21, biological features and survival in gastric cancer patients.

    目的:探讨胃癌RUNX3蛋白表达对细胞周期蛋白的影响及其与胃癌患者生存和生物学特性的关系。

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  • To investigate the effect of benazepril on expression of cyclin kinase inhibitor P21 CIP1 protein in renal tissue of diabetic rats.

    目的:探讨苯那普利对糖尿病大鼠肾组织细胞周期蛋白激酶抑制剂p 21 CIP1蛋白表达的影响。

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  • Purpose:Find the relationship between the expressions of P21 oncogene, P16 antioncogene and the biological action of the bladder cancer.

    目的:探讨癌基因P2 1和抑癌基因P16的表达与膀胱癌生物学行为之间的关系。

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  • Conclusion: the expression of serum P21 and the incidences of chronic rhinitis and pharyngitis in coke oven workers were higher than general people.

    结论:焦炉工血清p 21蛋白表达水平高于一般人群,其慢性鼻炎和咽炎的患病率亦高于一般人群。

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  • Conclusion Antisense telomerase RNA can block telomerase activity in SMMC7721 cells accompanied simultaneously with an increased P16 and P21 expression levels.

    结论转染反义端粒酶RNA在封闭细胞端粒酶活性表达的同时,伴发P21与P16表达水平的升高。

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  • METHODS: the expressions of CKI, P27, P21 and proliferating cell nuclear antigen (PCNA) were tested in different regions of corneal epithelium by SP immunohistochemistry.

    方法:应用SP免疫组化法,检测P 21, P27等细胞周期依赖性激酶抑制剂和增殖细胞核抗原(pcna)在角膜上皮不同部位的表达情况。

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  • Objective: To investigate the roles and relationships among ERK pathway, P53/P21 and CDK5/P35 during neuronal differentiation using a differentiative model of PC12 cells induced by NGF.

    目的:利用NGF诱导的PC12细胞分化模型,探讨ERK通路、P53/P21蛋白和CDK5/P35蛋白在神经元分化过程中的可能作用及相互关系。

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  • Methods The expressions of P21 and P27 protein in normal ovarian tissue(10 cases), benign ovarian tumor (10 cases) and ovarian carcinoma (30 cases) were analyzed by immunohistochemistry technique.

    方法应用免疫组织化学方法检测10份正常卵巢组织、10份良性卵巢肿瘤以及30份恶性卵巢肿瘤组织中P21和P27蛋白的表达。

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  • Methods The expressions of P21 and P27 protein in normal ovarian tissue(10 cases), benign ovarian tumor (10 cases) and ovarian carcinoma (30 cases) were analyzed by immunohistochemistry technique.

    方法应用免疫组织化学方法检测10份正常卵巢组织、10份良性卵巢肿瘤以及30份恶性卵巢肿瘤组织中P21和P27蛋白的表达。

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