Osteopontin(OPN) is an extracellular matrix protein.
骨桥蛋白（OPN）是一种细胞外基质蛋白。
This article reviews the effect of osteopontin on onset of osteoporosis.
本文就骨桥蛋白在骨质疏松症的发病中所起作用作一综述。
Osteopontin expression could be stimulated directly by nicotine treatment.
尼古丁能直接刺激骨桥蛋白的产生。
Previous studies have established a relation between osteopontin and the liver.
以往的一些研究确定了骨桥蛋白与肝脏的一些关系。
Another showed that mice lacking the osteopontin gene developed less hepatic injury.
另一项研究发现缺少骨桥蛋白基因的小鼠不易出现肝损伤。
AIM To study osteopontin (OPN) change in femur and marrow under weightlessness stimulation.
目的研究模拟失重大鼠股骨和骨髓中骨桥素(opn)的形态学变化。
The changes of BMP2 and osteopontin were detected by immunohistochemistry and Western blotting.
骨形态发生蛋白2与骨桥蛋白检测：采用免疫组织化学染色与蛋白印迹方法。
Effect of Vitamin d, Vitamin K, testosterone and estradiol on expressions of osteopontin in rat.
维生素d，维生素k，雌二醇和睾酮对结石模型大鼠肾骨桥蛋白表达的影响。
Objective To investigate the expression of osteopontin (OPN) in non-small cell lung cancer (NSCLC).
目的研究骨桥蛋白(OPN)在非小细胞肺癌(NSCLC)中的表达。
The researchers also found that osteopontin gene expression triggered the expression of profibrogenic genes.
研究者也发现骨桥蛋白基因的表达触发了纤维蛋白酶原基因的表达。
Objective: To evaluate the effect of osteopontin as serum tumor marker on the diagnosis of pancreatic cancer.
目的：评价骨桥蛋白作为肿瘤血清标记物在胰腺癌诊断中的作用。
Objective: To explore the expression and distribution of osteopontin in local lesions of scleroderma patients.
目的：探讨骨桥蛋白在硬皮病患者局部皮损表达和分布情况。
Objective: To evaluate the effect of osteopontin (OPN) as serum tumor marker on the diagnosis of pancreatic cancer.
目的：评价骨桥蛋白(OPN)作为肿瘤血清标记物在胰腺癌诊断中的作用。
Osteopontin is a part of cell wall, which plays an important role in adherence, migration of cell, repair of tissue.
骨桥蛋白是细胞外基质的重要组成部分，在细胞的黏附与迁移、组织的修复、细胞的信号转导中有重要的作用。
Objective To investigate the relationship between the expression and regulation of osteopontin (OPN) and urolithiasis.
目的探讨骨桥蛋白(OPN)的表达和调控与尿石症的关系。
Objective To explore the expression and clinical significance of osteopontin (OPN) in patients with pancreatic cancer.
目的探讨骨桥蛋白(OPN)在胰腺癌组织中表达的临床意义。
Osteopontin(OPN) is an integrin-binding protein, believed to be involved in a variety of physiological cellular functions.
骨桥蛋白（OPN）是分泌性细胞的细胞外基质蛋白，与细胞的多种生理功能关系密切。
Osteopontin is a multifunctional phosphoprotein containing GRGDS sequence which functions in cell adhesion and chemotaxis.
骨桥蛋白是一种具有多种功能的磷酸化糖蛋白，其中含有特异的与细胞黏附及迁移有关的GRGDS序列。
Osteopontin-c was detected in 16 of the 20 tumors (80%) and was undetectable in the 22 normal specimens, the researchers report.
研究人员报告在20个肿瘤中有16检测到骨桥蛋白C（ 80 ％ ） ，但在22例正常标本中没有被检测到。
Objective To investigate the expression of osteopontin in gastric cancer and its correlation with inducible nitric oxide synthase.
目的研究骨桥蛋白在胃癌组织中的表达及其与诱导型一氧化氮合成酶表达的关系。
Objective To investigate dynamic expression of CD44 and its ligand osteopontin (OPN) on the formation of alcoholic hepatic fibrosis.
目的动态观察CD44及其配体骨调素(opn)在大鼠酒精性肝纤维化形成过程巾的表达并初步探讨其作用。
Objective to probe into the relationship between plasma osteopontin (OPN) level and the development of coronary heart disease (CHD).
目的探讨血浆骨桥蛋白(OPN)水平与冠心病发病之间的关系。
Recent studies confirmed that osteopontin is highly expressed in liver hydatid cyst and may play an important role in cyst formation.
近年来的研究证实，骨桥蛋白在肝棘球蚴的外囊中大量表达，并在其形成过程中起重要作用。
Objective To explore the expression of osteopontin (OPN) in oral mucosal epithelium of oral local lesion in patients with oral leukoplakia (OLK).
目的研究口腔白斑(olk)患者病损局部黏膜上皮细胞骨桥蛋白(OPN)表达情况。
Female wild-type mice on an ethanol-rich diet had 4 times as much alanine aminotransferase (ALT), indicating liver injury, than mice lacking the osteopontin gene.
雌性野生种小鼠的丙氨酸转氨酶是基因敲除鼠的4倍，这提示肝损伤的存在；
Osteopontin is a glycoprotein involved in inflammation, angiogenesis, and metastasis, and has been found in higher levels in cancer patients with metastatic disease.
骨桥蛋白是一种参与炎症、血管生成和转移的糖蛋白，研究发现其在发生癌症转移的病人中血中表达水平较高。
Methods Use immunohistochemistry method to detect the osteocalcin, bone sialoprotein and osteopontin expressions in tumor cells and matrix of 50 cases of osteosarcoma.
方法采用免疫组化方法检测OC、BSP、OPN在50例各型骨肉瘤肿瘤细胞、基质中的表达。
Effect of eucommia bark on osteopontin and osteoprotegerin expressions in rat bone marrow stem cells: Is there any difference between water extract and methanol extract?
杜仲对大鼠骨髓基质细胞骨桥蛋白和骨保护素表达的影响水提液与醇提液有区别吗？
After analyzing the plasma levels of 80 known human cytokines, the investigators identified osteopontin as a necessary factor for recruitment of BMCs and subsequent tumor growth.
在分析了80种已知的人类细胞因子的血清中水平后，研究者们发现骨桥蛋白作为一种必需因子对BMC的聚集和以后的肿瘤生长具有重要作用。
Objective To investigate the expression of osteopontin (OPN) and monocyte chemoattractant protein 1(MCP-1)and the effect of simvastatin on them in diet-hypercholesterolemia rats.
目的观察高脂血症肾损害大鼠肾组织中骨调素（OPN）和单核细胞趋化蛋白1 （MCP-1）表达变化及辛伐他汀对其表达的影响。
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