Objective To study the effects of domestic incadronate(ICD) on osteoclastic bone resorbing lacunae.
目的研究国产因卡磷酸钠（ICD）对破骨细胞性骨吸收的作用。
We compared th effect of interleukin-1 (IL1) alone or with osteoblasts on osteoclastic bone re-sorption.
建立了成骨细胞和破骨细胞共同培养体系，探讨了白细胞介素-1（IL1）促进骨吸收的作用机理。
It is suggested that APD could directly suppress osteoclastic bone resorption and might be effective in osteoporosis.
提示APD具有较强的直接抑制破骨细胞性骨吸收的作用，对骨质疏松症可能有一定的疗效。
Conclusion: Nylestriol can inhibit expression of IL 6 mRNA, reduce osteoclastic bone resorption and decrease loss of bone mass.
结论：尼尔雌醇可以抑制IL6基因表达，从而抑制破骨细胞骨吸收，减少骨量丢失。
The effect of ICD was stronger than that of APD. Conclusion ICD directly suppresses osteoclastic bone resorption and may be effective in osteoporosis.
结论ICD具有较强的直接抑制破骨细胞性骨吸收的作用，对骨质疏松症可能有一定的治疗作用。
The effect of ICD was stronger than that of APD. Conclusion ICD directly suppresses osteoclastic bone resorption and may be effective in osteoporosis.
结论ICD具有较强的直接抑制破骨细胞性骨吸收的作用，对骨质疏松症可能有一定的治疗作用。
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