RT PCR assay showed induced cells expressed osteocalcin.
PCR显示诱导细胞表达成骨细胞特异的骨钙素。
The ALP activity and the expression of osteocalcin increased.
成纤维细胞alp活性增高、骨钙素表达增多，细胞内alp染色加深。
Binding of osteocalcin to calcium is necessary for normal bone formation.
骨钙素与钙结合对正常骨骼结构来说是至关重要的。
Mice that produced no osteocalcin lacked this hormonal weight-control mechanism.
未能产生骨钙素的老鼠缺乏这种激素的体重控制机制。
Results: Relationship between serum osteocalcin and periodontitis has not be defined.
结果：血清骨钙素与牙周病之间的关系尚未确定。
The researchers decided to examine the role of osteocalcin, a protein produced by osteoblasts.
研究人员决定研究骨钙素(造骨细胞产生的蛋白质)的作用。
The hMSCs in induced culture showed cytochemical staining for ALP and osteocalcin expression.
诱导培养细胞碱性磷酸酶染色，骨钙素免疫组化染色阳性。
Because osteocalcin is produced only by osteoblasts yet ACTS on cells far away in the pancreas.
因为骨钙素仅由造骨细胞产生但是却对远在胰腺的细胞起作用。
Additional experiments suggested that osteocalcin regulates insulin sensitivity through adiponectin.
附加实验表明，骨钙素通过脂联素调节胰岛素敏感性。
Accumulation of inactive osteocalcin instead nudges osteoclasts into action, causing them to gobble up bone.
而惰性骨钙蛋白的积累反过来会推动破骨细胞发生作用，使他们逐渐的消解骨骼。
Osteocalcin and bone specific alkaline phosphatase in blood had a positive correlation with bone density.
血中骨钙素及骨碱性磷酸酶水平与骨密度呈正相关。
We extracted and purified osteocalcin(BGP) from calf femur by gel filtration, FPLC and HPLC subsequently.
本研究用凝胶过滤，快速液相（FPLC）和高压液相（HPLC）成功地从小牛股骨提取和纯化了骨钙素（BGP）。
A few years ago, the same group found that osteocalcin plays a role in maintaining the body's glucose levels.
几年前，该研究组就发现造骨细胞影响了人体的葡萄糖含量水平。
To do so, they used some mice that had been bred to lack the gene that instructs the body to make osteocalcin.
为此，他们用老鼠来做研究，这些老鼠天生缺乏一种可以诱导躯体产生骨钙素的基因。
Research shows that the molecule osteocalcin, produced by bone cells, may help to regulate blood glucose levels.
研究表明，骨钙素分子，产生骨细胞，可以帮助调节血糖水平。
Objective To observe the influence of acupuncture on osteocalcin in infantile encephalopathy and mental retardation.
目的观察针刺对小儿脑瘫及精神发育迟滞(或迟缓)骨钙素的影响。
Objective: To investigated the levels of osteocalcin (OC) in the peri-implant sulcular fluid (PISF) from dental implants.
目的研究牙种植体周围组织不同状态与牙种植体周围龈沟液（PISF）中骨钙素（OC）的关系。
Interestingly, it appears that insulin signaling in osteoblasts induced osteocalcin activation by stimulating osteoclast activity.
有趣的是，似乎成骨细胞中的胰岛素信号通过刺激破骨细胞活性诱导骨钙素活性。
Indeed, when Dr Karsenty fed his mice traces of osteocalcin, their blood sugar levels dropped and their insulin production increased.
确实，当卡森提(Karsenty)博士给他的老鼠进食微量骨钙素时，它们的血糖水平降低，胰岛素总量反而增加。
Main Outcome Measure: The relationship between serum 25ohd, serum PTH, and serum osteocalcin and 24-h urine N-telopeptides was evaluated.
主要观察指标：对血清25ohd、血清甲状旁腺激素、血清骨钙素和24小时尿n -末端肽的关系进行了评价。
Objective To investigate the effect of progestin on the gene expression and production of osteocalcin in vitro in fetal rat calvarial osteoblasts.
目的观察孕激素对离体成骨细胞骨钙素基因表达及其合成的影响。
Bone is already known to release hormones. A few years ago, the same group found that osteocalcin plays a role in maintaining the body's glucose levels.
骨骼分泌激素的说法已是为人熟知。几年前，该研究组就发现造骨细胞影响了人体的葡萄糖含量水平。
Karsenty calls this process a "feed-forward" loop, where insulin stimulates the production of osteocalcin, which in turn stimulates more insulin production.
卡尔·桑迪将这一过程称为一种“前馈”循环，在此过程中胰岛素刺激骨钙蛋白的生成，而骨钙蛋白反过来可以刺激更多胰岛素的产生。
To find out if this effect on testosterone production might affect mice's fertility, the team knocked out the gene for osteocalcin in a group of the rodents.
为查明骨钙素对睾丸激素的影响是否会影响老师的生育能力，该研究组将一组老鼠的骨钙素基因取出。
Importantly, this function of insulin signaling in osteoblasts was achieved through the negative regulation of osteocalcin carboxylation and bioavailability.
重要的是，成骨细胞中胰岛素信号的这一功能通过骨钙素羧基化和生物利用度的负向调控功能来实现。
RESULTS: Before treatment, there were significant differences in the BMD of L2-4 and femoral neck, osteocalcin, TPINP and VAS scores between 2 groups (P>0.05).
结果：治疗前，两组患者L2～4和股骨颈的BMD、骨钙素、TPINP、VAS评分比较，差异均无统计学意义（P＞0.05）。
Conclusion progesterone was involved directly in osteocalcin production by regulating gene expression and this effect of progesterone was time and dose dependent.
结论孕酮从基因水平调节离体胎鼠成骨细胞骨钙素的生成，这种调节呈现时间及剂量依赖。
However, this research is in its very early stages and much more needs to be done before we can establish a conclusive link between osteocalcin in bones and diabetes.
然而，这项研究是在非常早期阶段，更需要做的，才可以建立一个确凿的联系骨钙骨骼和糖尿病。
Methods Use immunohistochemistry method to detect the osteocalcin, bone sialoprotein and osteopontin expressions in tumor cells and matrix of 50 cases of osteosarcoma.
方法采用免疫组化方法检测OC、BSP、OPN在50例各型骨肉瘤肿瘤细胞、基质中的表达。
Methods Use immunohistochemistry method to detect the osteocalcin, bone sialoprotein and osteopontin expressions in tumor cells and matrix of 50 cases of osteosarcoma.
方法采用免疫组化方法检测OC、BSP、OPN在50例各型骨肉瘤肿瘤细胞、基质中的表达。
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