The formulation and drug-related biopharmaceutical aspects of these systems that govern oral absorption have been widely studied.
这些给药系统的口服制剂的组成和与药物相关的生物药剂学方面已经进行了广泛的研究。
Background: As one of the histamine H_2 receptor antagonist, the oral absorption of famotidine is not complete, its bioavailability is about 37%-50%.
背景：法莫替丁作为组胺H_2受体拮抗剂，其口服吸收不完全，生物利用度约为37% - 50%。
Prodrug is an effective way to improve the oral absorption of the drugs which belong to Biopharmaceuticals Classification System(BCS) class III and IV.
前药研究是提高生物药剂学分类系统中第III和IV类药物口服吸收的有效途径之一。
Oral absorption of hydrophobic drugs can be significantly improved using lipid-based non-particulate drug delivery systems, which avoid the dissolution step.
利用非微粒脂质给药系统，药物不必经过溶出的步骤，从而可以显著的提高疏水性药物的口服吸收。
However, for the sake of its low oral absorption and bioavailability, now in clinic Puerarin is administrated only by vein injection, which is inconvenient for patients and limits its clinical use.
由于其口服难吸收、生物利用度低的原因，临床只用于静脉给药。这不仅给患者带来用药的不便，而且也限制了葛根素的临床应用。
"Recently, we discovered that grapefruit and these other fruit juices substantially decrease the oral absorption of certain drugs undergoing intestinal uptake transport," AFP quoted Bailey as saying.
“最近，我们发现柚子汁和其他果汁大大地减少了某些口服药物在肠道内摄入转移的量。”支持贝利的AFP如是说。
The solubility, stability in gastrointestinal tract, membrane permeability and presystemic metabolism of drugs were the major factors on oral drug absorption.
药物的溶解性，在胃肠道中的稳定性，膜的通透性和全身代谢是影响口服药物吸收的主要因素。
For oral administration, the most common route, absorption refers to the transport of drugs across membranes of the epithelial cells in the GI tract.
口服是最常用的给药途径，其吸收涉及药物通过胃肠道上皮细胞膜的转运。
Ntrimethyl chitosan chloride, a partially quaternised derivative of chitosan, which is soluble in neutral and basic environment, can be used as an absorption enhancer of oral peptide drugs.
氯化N-三甲基壳聚糖是壳聚糖的部分季铵化衍生物，能溶于中性及碱性环境中，可作为肽类药物的口服吸收促进剂。
METHODS Sum up the studies of the mechanism and influence factors of Chitosan and its Derivatives in oral drug absorption.
方法以国内外发表的文献为依据，总结归纳了壳聚糖及其衍生物促进药物口服吸收中的机理及影响因素。
Results The solubility, stability in gastrointestinal tract, membrane permeability and presystemic metabolism of drugs were the major factors on oral drug absorption.
结果药物的溶解性、稳定性、膜通透性和首过作用等生物药剂学性质是影响药物口服后经胃肠道吸收的主要因素。
Objective To review the impacts of biopharmaceutical characteristics on oral drug absorption.
目的综述药物的生物药剂学性质对药物口服吸收的影响。
Oral bacitracin zinc is almost no absorption, most within 2 days with the feces.
杆菌肽锌内服几乎不吸收，大部分在2天内随粪便排出。
It is indicates that the concentrated capsule of 1, 25-dihydroxyvitamin D3 oral preparation would be in favor of absorption and utilization.
这提示1,25二羟基维生素d 3口服制剂的浓缩剂型，将有利于其吸收利用。
But these platinum - based drugs used in the clinical at present have poor absorption by the oral route.
但目前这些临床应用的铂族金属抗肿瘤药口服活性低，都是静脉途径给药。
Thee oral mucosa has a thin epithelium and a rich vascularity that favors absorption, but contact is usually too brief, even for drugs in solution, for appreciable absorption to occur.
口腔粘膜上皮很薄，血管丰富，有利于药物吸收。但是，接触的时间太短暂，即使是溶液剂也来不及等到明显的吸收发生。
Overuse may decrease absorption of nutrients and oral medications due to increased speed of transit through the intestines.
过度使用可能会通过减少肠道对营养物质和适当的过境速度增加口服药物的吸收。
The synthesis, physico-chemical properties, absorption enhancing properties, cytotoxic evaluation and solid oral dosage forms of N-trimethyl chitosan chloride were summarized.
对氯化N-三甲基壳聚糖的制备、理化性质、促吸收机制、细胞毒性评价及制剂等方面作一综述。
The 3rd 150 days:To test the enzymes oral metabolic characteristics (the rate of intestinal absorption);
第三个150日：测试酶的口服代谢特性（肠道吸收率）；
The oral mucosa has a thin epithelium and a rich vascularity that favors absorption, but contact is usually too brief, even for drugs in solution, for appreciable absorption to occur.
口腔粘膜上皮很薄，血管丰富，有利于药物吸收。但是，接触的时间太短暂，即使是溶液剂也来不及等到明显的吸收发生。
The oral mucosa has a thin epithelium and a rich vascularity that favors absorption, but contact is usually too brief, even for drugs in solution, for appreciable absorption to occur.
口腔粘膜上皮很薄，血管丰富，有利于药物吸收。但是，接触的时间太短暂，即使是溶液剂也来不及等到明显的吸收发生。
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