Feeling down, depressed, or hopeless.
心情忧郁，绝望，无助，或悲伤。
Or they may urge you to visit your doctor when you feel overly anxious, sad or hopeless.
当你过度焦虑、忧伤、绝望时，朋友会陪你看医生；
If one is in a situation that is intolerable or hopeless in its destructiveness then certainly it is foolish to continue.
假如一个人处于一个其毁灭性令人无法忍受或毫无希望的处境，那么当然，继续下去是愚蠢的。
But no matter how tired or hopeless I am feeling, hip-hop helps me look beyond my own circumstances to find the determination I need to move forward.
但是无论我感觉多么劳累与绝望，hip - hop音乐已经使我不再为了眼前的苦难而唉声叹气，它使我看得更远，去寻找前进道路上所必须的决心和毅力。
Know the signs of depression: apathy, loss of energy, loss of appetite, impaired concentration, loss of interest in favorite activities, feeling guilty, worthless, or hopeless.
了解忧郁症的征兆：冷漠，无精打采，没有胃口，集中力下降，对于曾经喜爱的活动失去兴趣，有负罪感，无价值感或是有绝望感。
The teenagers also answered a number of health-related questions, including some standard questions about "depressive tendencies" that gauge how often a person feels sad or hopeless.
这些青少年还回答了一些和健康相关的问题，其中包括一些和“抑郁倾向”有关的常规问题，这些问题可测算出一个人感到忧伤或绝望的频繁程度。
The teenagers also answered a number of health-related questions, including some standard questions about depressive tendencies that gauge how often a person feels sad or hopeless.
这些青少年还回答了一些和健康相关的问题，其中包括一些和抑郁倾向有关的常规问题，这些问题可测算出一个人感到忧伤或绝望的频繁程度。
However, if you find that you are sad, irritable, bored, or hopeless much of the time, or if you just can't seem to shake the blues, you might be depressed and need help from a counselor or doctor.
然而，如果你发现你某段时间很难过，焦躁，无聊，或者绝望，或者你看上去很由于，你可能情绪消沉，并且需要一个顾问或医生。
Someone who is happy and positive or someone who brings you down and makes you feel hopeless, or worse, guilty about even your smallest successes?
那些快乐积极的还是那些让你感到消沉绝望，或者更糟糕地让你为自己小小的成功感到内疚的人？
Usually when someone has a slip or is experiencing a relapse, they tend to believe that they have failed and that they are hopeless.
通常，当有些人犯了错或者经历着复发，他们会认为他们失败了，他们是无望的了。
So I don't want anybody feeling that if he or she is down here that it is hopeless at this point. It is not.
我不想让任何人感到，来到这的他或她，在这点上是无望的，不是这样。
Bipolar disorder causes dramatic mood swings from overly "high" and/or irritable to sad and hopeless, and then back again, often with periods of normal mood in between.
双相情感障碍导致激烈地在过分地高亢和/或易怒到悲伤与无望之间反复的情感波动，同时，常常有一个平稳的间歇期在两者之间。
Feeling hopeless, that nothing will ever change or get better.
患者感到无望，就是说事情不会再改变或变得更好。
According to Collins German dictionary, the word means "hopeless, miserable, wretched or inconsolable"
根据科林斯字典的解释，这个单词意为“绝望、痛苦、可怜或者悲惨至极”。
Feeling hopeless, worthless or helpless.
感觉无望、无助、无价值。
Remember that the above steps won't work if you can't write a song to save your life, your arranging ability is hopeless, or you don't put the requisite work into the show.
切记，要是你根本写不出一首拯救你生活的歌，抑或完全不懂编曲，又或者在演出现场没有做好必要的功课，那上面那些步骤也是白搭。
Alternately, if you're completely hopeless as a writer, handwrite her favorite poem or the lyrics to a song that means something to you as a couple (i.e., your wedding song).
要是你完全没希望写出点什么，就亲手抄一首对你们有特殊意义的，她最爱的诗或歌词(比如，你们婚礼上的歌曲)。
All history proves that the capitalists will never relinquish their property peacefully – to claim otherwise in the age of ‘Shock and Awe’ is either hopeless naivety or wilful deception.
历史已经证明：资本家们绝不会主动地让出他们的财产——在这个“震撼与威慑”的时代，对此持有疑议如果不是过于天真那就是故意的欺骗。
I couldn't describe my pursuers, or the model of car they were in. It was hopeless.
我无法描述追我的人的样子，也无法形容他们所坐的车的样式，所以毫无希望。
But a much bigger problem is the sense of despair and exclusion that makes going to school or seeking work seem a hopeless waste of time.
但是更为严重的问题是吉普赛人的绝望情绪和不被社会接受的现状，这使得入学或者找工作对他们而言变成了纯粹的浪费时间。
They may not be aware of signs and symptoms of depression, or they may feel too hopeless to address the issue.
他们可能是没注意到他们的症状，或是觉得没有解决的办法。
In a year or so, the situation may be irretrievably hopeless. It is pretty appalling now.
在一年多的时间里，可能这里的状况已没有一点希望，现在甚至到了令人骇人听闻的地步。
Probably once or twice a week we are sitting at dinner and Richard says, ‘The cortex is hopeless,’ and I say, ‘That's why I work on the worm.
有可能一周或两周一次我们吃饭时理查德会说：‘大脑皮层没希望了。’
Talking about feeling hopeless or feeling guilty.
谈到感觉无助或者有罪恶感。
Probably once or twice a week we are sitting at dinner and Richard says, ‘The cortex is hopeless, ’ and I say, ‘That’s why I work on the worm.’
有可能一周或两周一次我们吃饭时理查德会说：‘大脑皮层没希望了。’我会说：‘那正是我为何要研究蛔虫。’
Some may even feel hopeless or terribly depressed.
有的人甚至感到无望或者极度沮丧。
There is nothing that is hopeless or can't be done if you are resolute enough.
没有什么是无望或不能做，如果你是坚决不够。
His words either fell on deaf ears or the Lakers' defense truly is hopeless.
他的话如果不是耳边风的话，那么就是湖人的防守真的没希望了。
His words either fell on deaf ears or the Lakers' defense truly is hopeless.
他的话如果不是耳边风的话，那么就是湖人的防守真的没希望了。
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