Pedigree is one of the most general population structure in the genetic linkage analysis between human single genetic inheritance disease locus and genetic marker locus.
在人类单位点致病基因与遗传标记基因的遗传连锁分析中,家系是应用得最普遍的一种群体结构。
Analysis of LSF level in biopsy material may one day be used as a prognostic marker for HCC.
对活检标本lsf水平的分析,有朝一日可以被用来作为肝癌的预后指标。
Genotyping error has become one of important issues during the molecular marker detection studies, especially for the trace sample genotyping and forensic analysis.
基因分型错误已成为目前分子标记检测(如痕量样品分析、法医学鉴定)过程中愈发受到重视的问题。
Microsatellite marker is one of the frequently used molecular markers. It has been used in the genotype identification, pedigree analysis and estimation of genetic distance.
微卫星是近几年来应用较多的一种分子标记,可有效地进行基因鉴定与系谱分析,并可估算群体间的遗传距离。
Conclusions it suit to the small pedigree data. Multipoint linkage analysis can not only calculate the recombination and map distance, but also localize the disease gene to one side of the marker.
结论适用于小家系资料的多位点连锁分析,不仅能算出致病基因与标记的重组率和遗传距离,而且能把致病基因定位至遗传标记的一侧。
Conclusions it suit to the small pedigree data. Multipoint linkage analysis can not only calculate the recombination and map distance, but also localize the disease gene to one side of the marker.
结论适用于小家系资料的多位点连锁分析,不仅能算出致病基因与标记的重组率和遗传距离,而且能把致病基因定位至遗传标记的一侧。
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