It's a complex disease and there are so many factors responsible that it's difficult to blame it on one specific issue.
乳腺癌是一种复杂的疾病，有如此多的引发因素，而仅仅只是责备体重这一个因素是很难理解的。
It is often difficult to reproduce an issue on just one clone.
在仅仅一个副本上重现问题通常非常困难。
One London traders' representative calls this "the single most difficult issue" in implementing MiFID.
一名伦敦的交易者代表称这是在执行MiFID中遇到的单个最困难的问题。
Money is one of the most difficult topics to deal with in a marriage. It is important to address this issue from the very beginning of your marriage.
在婚姻中，钱是最困难的话题之一，从婚姻的一开始就必须讨论清楚。
The issue of whether to have a second child is one of the most difficult issues that parents nowadays face.
是否有第二个孩子的问题之一是，现在的父母所面临的最困难的问题。
ZAKARIA: the currency issue is a difficult one, the renminbi.
扎卡里亚：人民币汇率问题是复杂且困难的。
This issue is one of the most difficult, yet most important a couple should face before getting seriously involved.
这个问题是最艰难的一个了，然而也是最重要的，是两个人在真正进入彼此之前应该面对的问题。
This is a cultural issue, one that is often difficult for many organizations to adopt.
这是一个文化问题，通常难以被很多组织采用。
Coordinated control issue is one of the difficult control issues of parallel hybrid electric system.
动态协调控制是并联混合动力系统控制的难点之一。
One hand, recruiters, he there is a credibility issue, recruitment is a very difficult thing, but also a very simple matter.
一方面对招聘者来说，他存在一个诚信的问题，招聘是一个很艰难的事，同时也是一个很简单的事。
It is rather a difficult issue for statistical agencies how to estimate price index accurately, while quality adjustment is one of those factors which influence the accuracy.
如何准确地计算价格指数成为困扰各国统计机构的一个难题，而质量调整是目前影响价格指数准确性的重要因素之一。
Duty consumption can be one way for the senior executives' embezzling of the corporate residual assets, which poses a difficult issue for the enterprise nowadays.
在职消费是企业高管人员侵蚀公司剩余资源的一种方式，也是当前企业普遍面临的一个现实难题。
Refactoring is one key issue during the software evolution, and is a complex and difficult task.
重构是软件系统不断演化的关键之一，也是一项复杂而又困难的活动。
One reason is that it is more difficult to implement some complicated operations like VCR operation, and another reason is the obstruction to P2P VoD by the issue of copyright of media source.
一方面是因为点播当中的高度交互性需求（VCR操作）实现的复杂程度较高，另一方面是节目源版权因素对P2P点播技术的阻碍。
The issue is a difficult one for HSBC, which in December said it believed fewer than 10 clients were affected by the theft.
这对汇丰控股而言是一个棘手的问题。去年12月，它说相信只有不到10名客户受到数据失窃的影响。
The issue is a difficult one for HSBC, which in December said it believed fewer than 10 clients were affected by the theft.
这对汇丰控股而言是一个棘手的问题。去年12月，它说相信只有不到10名客户受到数据失窃的影响。
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