Long-term treatment with the second-generation nucleoside analogue lamivudine (lam) efficiently inhibits HBV replication with frequent viral polymerase mutations.
二代拉米夫定的长期应用可以有效地抑制病毒多聚酶突变频繁的HBV发生复制。
Effective treatment options for individuals with chronic hepatitis B infection were limited until 1998 when lamivudine, the first nucleoside analogue drug, was introduced.
1998年首个核苷类似物药物拉米夫定推出之前，慢性乙肝病毒感染者可选的有效治疗途径一直都非常有限。
Effective treatment options for individuals with chronic hepatitis B infection were limited until 1998 when lamivudine, the first nucleoside analogue drug, was introduced.
1998年首个核苷类似物药物拉米夫定推出之前，慢性乙肝病毒感染者可选的有效治疗途径一直都非常有限。
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